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Sequence of SGK1_HUMAN

EC Number:2.7.11.1

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
non-specific serine/threonine protein kinase
O00141
Homo sapiens
431
48942
Reaction
ATP + a [protein]-(L-serine/L-threonine) = ADP + a [protein]-(L-serine/L-threonine) phosphate
Other sequences found for EC No. 2.7.11.1

General information:

Sequence
show sequence in fasta format
  0 MTVKTEAAKG TLTYSRMRGM VAILIAFMKQ RRMGLNDFIQ KIANNSYACK HPEVQSILKI
 60 SQPQEPELMN ANPSPPPSPS QQINLGPSSN PHAKPSDFHF LKVIGKGSFG KVLLARHKAE
120 EVFYAVKVLQ KKAILKKKEE KHIMSERNVL LKNVKHPFLV GLHFSFQTAD KLYFVLDYIN
180 GGELFYHLQR ERCFLEPRAR FYAAEIASAL GYLHSLNIVY RDLKPENILL DSQGHIVLTD
240 FGLCKENIEH NSTTSTFCGT PEYLAPEVLH KQPYDRTVDW WCLGAVLYEM LYGLPPFYSR
300 NTAEMYDNIL NKPLQLKPNI TNSARHLLEG LLQKDRTKRL GAKDDFMEIK SHVFFSLINW
360 DDLINKKITP PFNPNVSGPN DLRHFDPEFT EEPVPNSIGK SPDSVLVTAS VKEAAEAFLG
420 FSYAPPTDSF L
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
99251
Waldegger S.,Barth P.,Raber G.,Lang F.
Cloning and characterization of a putative human serine/threonine protein kinase transcriptionally modified during anisotonic and isotonic alterations of cell volume.
Proc. Natl. Acad. Sci. U.S.A.
94
4440-4445
1997
99252
Waldegger S.,Erdel M.,Nagl U.O.,Barth P.,Raber G.,Steuer S.,Utermann G.,Paulmichl M.,Lang F.
Genomic organization and chromosomal localization of the human SGK protein kinase gene.
Genomics
51
299-302
1998
99253
Raikwar N.S.,Snyder P.M.,Thomas C.P.
An evolutionarily conserved N-terminal Sgk1 variant with enhanced stability and improved function.
Am. J. Physiol.
295
0-0
2008
99256
Ota T.,Suzuki Y.,Nishikawa T.,Otsuki T.,Sugiyama T.,Irie R.,Wakamatsu A.,Hayashi K.,Sato H.,Nagai K.,Kimura K.,Makita H.,Sekine M.,Obayashi M.,Nishi T.,Shibahara T.,Tanaka T.,Ishii S.,Yamamoto J.,Saito K.,Kawai Y.,Isono Y.,Nakamura Y.,Nagahari K.,Murakami K.,Yasuda T.,Iwayanagi T.,Wagatsuma M.,Shiratori A.,Sudo H.,Hosoiri T.,Kaku Y.,Kodaira H.,Kondo H.,Sugawara M.,Takahashi M.,Kanda K.,Yokoi T.,Furuya T.,Kikkawa E.,Omura Y.,Abe K.,Kamihara K.,Katsuta N.,Sato K.,Tanikawa M.,Yamazaki M.,Ninomiya K.,Ishibashi T.,Yamashita H.,Murakawa K.,Fujimori K.,Tanai H.,Kimata M.,Watanabe M.,Hiraoka S.,Chiba Y.,Ishida S.,Ono Y.,Takiguchi S.,Watanabe S.,Yosida M.,Hotuta T.,Kusano J.,Kanehori K.,Takahashi-Fujii A.,Hara H.,Tanase T.-O.,Nomura Y.,Togiya S.,Komai F.,Hara R.,Takeuchi K.,Arita M.,Imose N.,Musashino K.,Yuuki H.,Oshima A.,Sasaki N.,Aotsuka S.,Yoshikawa Y.,Matsunawa H.,Ichihara T.,Shiohata N.,Sano S.,Moriya S.,Momiyama H.,Satoh N.,Takami S.,Terashima Y.,Suzuki O.,Nakagawa S.,Senoh A.,Mizoguchi H.,Goto Y.,Shimizu F.,Wakebe H.,Hishigaki H.,Watanabe T.,Sugiyama A.,Takemoto M.,Kawakami B.,Yamazaki M.,Watanabe K.,Kumagai A.,Itakura S.,Fukuzumi Y.,Fujimori Y.,Komiyama M.,Tashiro H.,Tanigami A.,Fujiwara T.,Ono T.,Yamada K.,Fujii Y.,Ozaki K.,Hirao M.,Ohmori Y.,Kawabata A.,Hikiji T.,Kobatake N.,Inagaki H.,Ikema Y.,Okamoto S.,Okitani R.,Kawakami T.,Noguchi S.,Itoh T.,Shigeta K.,Senba T.,Matsumura K.,Nakajima Y.,Mizuno T.,Morinaga M.,Sasaki M.,Togashi T.,Oyama M.,Hata H.,Watanabe M.,Komatsu T.,Mizushima-Sugano J.,Satoh T.,Shirai Y.,Takahashi Y.,Nakagawa K.,Okumura K.,Nagase T.,Nomura N.,Kikuchi H.,Masuho Y.,Yamashita R.,Nakai K.,Yada T.,Nakamura Y.,Ohara O.,Isogai T.,Sugano S.
Complete sequencing and characterization of 21,243 full-length human cDNAs.
Nat. Genet.
36
40-45
2004
99257
Mungall A.J.,Palmer S.A.,Sims S.K.,Edwards C.A.,Ashurst J.L.,Wilming L.,Jones M.C.,Horton R.,Hunt S.E.,Scott C.E.,Gilbert J.G.R.,Clamp M.E.,Bethel G.,Milne S.,Ainscough R.,Almeida J.P.,Ambrose K.D.,Andrews T.D.,Ashwell R.I.S.,Babbage A.K.,Bagguley C.L.,Bailey J.,Banerjee R.,Barker D.J.,Barlow K.F.,Bates K.,Beare D.M.,Beasley H.,Beasley O.,Bird C.P.,Blakey S.E.,Bray-Allen S.,Brook J.,Brown A.J.,Brown J.Y.,Burford D.C.,Burrill W.,Burton J.,Carder C.,Carter N.P.,Chapman J.C.,Clark S.Y.,Clark G.,Clee C.M.,Clegg S.,Cobley V.,Collier R.E.,Collins J.E.,Colman L.K.,Corby N.R.,Coville G.J.,Culley K.M.,Dhami P.,Davies J.,Dunn M.,Earthrowl M.E.,Ellington A.E.,Evans K.A.,Faulkner L.,Francis M.D.,Frankish A.,Frankland J.,French L.,Garner P.,Garnett J.,Ghori M.J.,Gilby L.M.,Gillson C.J.,Glithero R.J.,Grafham D.V.,Grant M.,Gribble S.,Griffiths C.,Griffiths M.N.D.,Hall R.,Halls K.S.,Hammond S.,Harley J.L.,Hart E.A.,Heath P.D.,Heathcott R.,Holmes S.J.,Howden P.J.,Howe K.L.,Howell G.R.,Huckle E.,Humphray S.J.,Humphries M.D.,Hunt A.R.,Johnson C.M.,Joy A.A.,Kay M.,Keenan S.J.,Kimberley A.M.,King A.,Laird G.K.,Langford C.,Lawlor S.,Leongamornlert D.A.,Leversha M.,Lloyd C.R.,Lloyd D.M.,Loveland J.E.,Lovell J.,Martin S.,Mashreghi-Mohammadi M.,Maslen G.L.,Matthews L.,McCann O.T.,McLaren S.J.,McLay K.,McMurray A.,Moore M.J.F.,Mullikin J.C.,Niblett D.,Nickerson T.,Novik K.L.,Oliver K.,Overton-Larty E.K.,Parker A.,Patel R.,Pearce A.V.,Peck A.I.,Phillimore B.J.C.T.,Phillips S.,Plumb R.W.,Porter K.M.,Ramsey Y.,Ranby S.A.,Rice C.M.,Ross M.T.,Searle S.M.,Sehra H.K.,Sheridan E.,Skuce C.D.,Smith S.,Smith M.,Spraggon L.,Squares S.L.,Steward C.A.,Sycamore N.,Tamlyn-Hall G.,Tester J.,Theaker A.J.,Thomas D.W.,Thorpe A.,Tracey A.,Tromans A.,Tubby B.,Wall M.,Wallis J.M.,West A.P.,White S.S.,Whitehead S.L.,Whittaker H.,Wild A.,Willey D.J.,Wilmer T.E.,Wood J.M.,Wray P.W.,Wyatt J.C.,Young L.,Younger R.M.,Bentley D.R.,Coulson A.,Durbin R.M.,Hubbard T.,Sulston J.E.,Dunham I.,Rogers J.,Beck S.
The DNA sequence and analysis of human chromosome 6.
Nature
425
805-811
2003
99259
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Genome Res.
14
2121-2127
2004
99260
Kobayashi T.,Deak M.,Morrice N.,Cohen P.
Characterization of the structure and regulation of two novel isoforms of serum- and glucocorticoid-induced protein kinase.
Biochem. J.
344
189-197
1999
99261
Kobayashi T.,Cohen P.
Activation of serum- and glucocorticoid-regulated protein kinase by agonists that activate phosphatidylinositide 3-kinase is mediated by 3-phosphoinositide-dependent protein kinase-1 (PDK1) and PDK2.
Biochem. J.
339
319-328
1999
99262
Lang F.,Klingel K.,Wagner C.A.,Stegen C.,Waerntges S.,Friedrich B.,Lanzendoerfer M.,Melzig J.,Moschen I.,Steuer S.,Waldegger S.,Sauter M.,Paulmichl M.,Gerke V.,Risler T.,Gamba G.,Capasso G.,Kandolf R.,Hebert S.C.,Massry S.G.,Broer S.
Deranged transcriptional regulation of cell-volume-sensitive kinase hSGK in diabetic nephropathy.
Proc. Natl. Acad. Sci. U.S.A.
97
8157-8162
2000
99263
Hayashi M.,Tapping R.I.,Chao T.H.,Lo J.F.,King C.C.,Yang Y.,Lee J.D.
BMK1 mediates growth factor-induced cell proliferation through direct cellular activation of serum and glucocorticoid-inducible kinase.
J. Biol. Chem.
276
8631-8634
2001
99264
Perrotti N.,He R.A.,Phillips S.A.,Haft C.R.,Taylor S.I.
Activation of serum- and glucocorticoid-induced protein kinase (Sgk) by cyclic AMP and insulin.
J. Biol. Chem.
276
9406-9412
2001
99265
Zhang B.H.,Tang E.D.,Zhu T.,Greenberg M.E.,Vojtek A.B.,Guan K.L.
Serum- and glucocorticoid-inducible kinase SGK phosphorylates and negatively regulates B-Raf.
J. Biol. Chem.
276
31620-31626
2001
99266
Brunet A.,Park J.,Tran H.,Hu L.S.,Hemmings B.A.,Greenberg M.E.
Protein kinase SGK mediates survival signals by phosphorylating the forkhead transcription factor FKHRL1 (FOXO3a).
Mol. Cell. Biol.
21
952-965
2001
99267
Snyder P.M.,Olson D.R.,Thomas B.C.
Serum and glucocorticoid-regulated kinase modulates Nedd4-2-mediated inhibition of the epithelial Na+ channel.
J. Biol. Chem.
277
5-8
2002
99268
Henke G.,Setiawan I.,Boehmer C.,Lang F.
Activation of Na+/K+-ATPase by the serum and glucocorticoid-dependent kinase isoforms.
Kidney Blood Press. Res.
25
370-374
2002
99269
Gamper N.,Fillon S.,Feng Y.,Friedrich B.,Lang P.A.,Henke G.,Huber S.M.,Kobayashi T.,Cohen P.,Lang F.
K(+) channel activation by all three isoforms of serum- and glucocorticoid-dependent protein kinase SGK.
Pflugers Arch.
445
60-66
2002
99270
Palmada M.,Embark H.M.,Yun C.,Bohmer C.,Lang F.
Molecular requirements for the regulation of the renal outer medullary K(+) channel ROMK1 by the serum- and glucocorticoid-inducible kinase SGK1.
Biochem. Biophys. Res. Commun.
311
629-634
2003
99271
Boehmer C.,Wilhelm V.,Palmada M.,Wallisch S.,Henke G.,Brinkmeier H.,Cohen P.,Pieske B.,Lang F.
Serum and glucocorticoid inducible kinases in the regulation of the cardiac sodium channel SCN5A.
Cardiovasc. Res.
57
1079-1084
2003
99272
Chun J.,Kwon T.,Kim D.J.,Park I.,Chung G.,Lee E.J.,Hong S.K.,Chang S.I.,Kim H.Y.,Kang S.S.
Inhibition of mitogen-activated kinase kinase kinase 3 activity through phosphorylation by the serum- and glucocorticoid-induced kinase 1.
J. Biochem.
133
103-108
2003
99273
Boehmer C.,Henke G.,Schniepp R.,Palmada M.,Rothstein J.D.,Broeer S.,Lang F.
Regulation of the glutamate transporter EAAT1 by the ubiquitin ligase Nedd4-2 and the serum and glucocorticoid-inducible kinase isoforms SGK1/3 and protein kinase B.
J. Neurochem.
86
1181-1188
2003
99274
Maiyar A.C.,Leong M.L.,Firestone G.L.
Importin-alpha mediates the regulated nuclear targeting of serum- and glucocorticoid-inducible protein kinase (Sgk) by recognition of a nuclear localization signal in the kinase central domain.
Mol. Biol. Cell
14
1221-1239
2003
99275
Embark H.M.,Boehmer C.,Vallon V.,Luft F.,Lang F.
Regulation of KCNE1-dependent K(+) current by the serum and glucocorticoid-inducible kinase (SGK) isoforms.
Pflugers Arch.
445
601-606
2003
99276
Palmada M.,Dieter M.,Speil A.,Boehmer C.,Mack A.F.,Wagner H.J.,Klingel K.,Kandolf R.,Murer H.,Biber J.,Closs E.I.,Lang F.
Regulation of intestinal phosphate cotransporter NaPi IIb by ubiquitin ligase Nedd4-2 and by serum- and glucocorticoid-dependent kinase 1.
Am. J. Physiol.
287
0-0
2004
99277
Boehmer C.,Embark H.M.,Bauer A.,Palmada M.,Yun C.H.,Weinman E.J.,Endou H.,Cohen P.,Lahme S.,Bichler K.H.,Lang F.
Stimulation of renal Na+ dicarboxylate cotransporter 1 by Na+/H+ exchanger regulating factor 2, serum and glucocorticoid inducible kinase isoforms, and protein kinase B.
Biochem. Biophys. Res. Commun.
313
998-1003
2004
99278
Embark H.M.,Setiawan I.,Poppendieck S.,van de Graaf S.F.,Boehmer C.,Palmada M.,Wieder T.,Gerstberger R.,Cohen P.,Yun C.C.,Bindels R.J.,Lang F.
Regulation of the epithelial Ca2+ channel TRPV5 by the NHE regulating factor NHERF2 and the serum and glucocorticoid inducible kinase isoforms SGK1 and SGK3 expressed in Xenopus oocytes.
Cell. Physiol. Biochem.
14
203-212
2004
99279
Diakov A.,Korbmacher C.
A novel pathway of epithelial sodium channel activation involves a serum- and glucocorticoid-inducible kinase consensus motif in the C terminus of the channel's alpha-subunit.
J. Biol. Chem.
279
38134-38142
2004
99280
Henke G.,Maier G.,Wallisch S.,Boehmer C.,Lang F.
Regulation of the voltage gated K+ channel Kv1.3 by the ubiquitin ligase Nedd4-2 and the serum and glucocorticoid inducible kinase SGK1.
J. Cell. Physiol.
199
194-199
2004
99281
Embark H.M.,Boehmer C.,Palmada M.,Rajamanickam J.,Wyatt A.W.,Wallisch S.,Capasso G.,Waldegger P.,Seyberth H.W.,Waldegger S.,Lang F.
Regulation of CLC-Ka/barttin by the ubiquitin ligase Nedd4-2 and the serum- and glucocorticoid-dependent kinases.
Kidney Int.
66
1918-1925
2004
99282
Wang D.,Sun H.,Lang F.,Yun C.C.
Activation of NHE3 by dexamethasone requires phosphorylation of NHE3 at Ser663 by SGK1.
Am. J. Physiol.
289
0-0
2005
99283
Palmada M.,Speil A.,Jeyaraj S.,Boehmer C.,Lang F.
The serine/threonine kinases SGK1, 3 and PKB stimulate the amino acid transporter ASCT2.
Biochem. Biophys. Res. Commun.
331
272-277
2005
99284
Boehmer C.,Rajamanickam J.,Schniepp R.,Kohler K.,Wulff P.,Kuhl D.,Palmada M.,Lang F.
Regulation of the excitatory amino acid transporter EAAT5 by the serum and glucocorticoid dependent kinases SGK1 and SGK3.
Biochem. Biophys. Res. Commun.
329
738-742
2005
99285
Shojaiefard M.,Christie D.L.,Lang F.
Stimulation of the creatine transporter SLC6A8 by the protein kinases SGK1 and SGK3.
Biochem. Biophys. Res. Commun.
334
742-746
2005
99286
David S.,Kalb R.G.
Serum/glucocorticoid-inducible kinase can phosphorylate the cyclic AMP response element binding protein, CREB.
FEBS Lett.
579
1534-1538
2005
99287
Zhou R.,Snyder P.M.
Nedd4-2 phosphorylation induces serum and glucocorticoid-regulated kinase (SGK) ubiquitination and degradation.
J. Biol. Chem.
280
4518-4523
2005
99288
Palmada M.,Boehmer C.,Akel A.,Rajamanickam J.,Jeyaraj S.,Keller K.,Lang F.
SGK1 kinase upregulates GLUT1 activity and plasma membrane expression.
Diabetes
55
421-427
2006
99289
Yang Y.C.,Lin C.H.,Lee E.H.
Serum- and glucocorticoid-inducible kinase 1 (SGK1) increases neurite formation through microtubule depolymerization by SGK1 and by SGK1 phosphorylation of tau.
Mol. Cell. Biol.
26
8357-8370
2006
99290
Cordas E.,Naray-Fejes-Toth A.,Fejes-Toth G.
Subcellular location of serum- and glucocorticoid-induced kinase-1 in renal and mammary epithelial cells.
Am. J. Physiol.
292
0-0
2007
99291
Jeyaraj S.,Boehmer C.,Lang F.,Palmada M.
Role of SGK1 kinase in regulating glucose transport via glucose transporter GLUT4.
Biochem. Biophys. Res. Commun.
356
629-635
2007
99292
Boehmer C.,Palmada M.,Kenngott C.,Lindner R.,Klaus F.,Laufer J.,Lang F.
Regulation of the epithelial calcium channel TRPV6 by the serum and glucocorticoid-inducible kinase isoforms SGK1 and SGK3.
FEBS Lett.
581
5586-5590
2007
99293
Lee E.J.,Chun J.,Hyun S.,Ahn H.R.,Jeong J.M.,Hong S.K.,Hong J.T.,Chang I.K.,Jeon H.Y.,Han Y.S.,Auh C.K.,Park J.I.,Kang S.S.
Regulation Fe65 localization to the nucleus by SGK1 phosphorylation of its Ser566 residue.
BMB Rep.
41
41-47
2008
99294
Garcia-Martinez J.M.,Alessi D.R.
mTOR complex 2 (mTORC2) controls hydrophobic motif phosphorylation and activation of serum- and glucocorticoid-induced protein kinase 1 (SGK1).
Biochem. J.
416
375-385
2008
99295
Daub H.,Olsen J.V.,Bairlein M.,Gnad F.,Oppermann F.S.,Korner R.,Greff Z.,Keri G.,Stemmann O.,Mann M.
Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.
Mol. Cell
31
438-448
2008
99296
Arteaga M.F.,Coric T.,Straub C.,Canessa C.M.
A brain-specific SGK1 splice isoform regulates expression of ASIC1 in neurons.
Proc. Natl. Acad. Sci. U.S.A.
105
4459-4464
2008
99297
Chen W.,Chen Y.,Xu B.E.,Juang Y.C.,Stippec S.,Zhao Y.,Cobb M.H.
Regulation of a third conserved phosphorylation site in SGK1.
J. Biol. Chem.
284
3453-3460
2009
99298
Won M.,Park K.A.,Byun H.S.,Kim Y.R.,Choi B.L.,Hong J.H.,Park J.,Seok J.H.,Lee Y.H.,Cho C.H.,Song I.S.,Kim Y.K.,Shen H.M.,Hur G.M.
Protein kinase SGK1 enhances MEK/ERK complex formation through the phosphorylation of ERK2: implication for the positive regulatory role of SGK1 on the ERK function during liver regeneration.
J. Hepatol.
51
67-76
2009
99299
Amato R.,D'Antona L.,Porciatti G.,Agosti V.,Menniti M.,Rinaldo C.,Costa N.,Bellacchio E.,Mattarocci S.,Fuiano G.,Soddu S.,Paggi M.G.,Lang F.,Perrotti N.
Sgk1 activates MDM2-dependent p53 degradation and affects cell proliferation, survival, and differentiation.
J. Mol. Med.
87
1221-1239
2009
99300
Oppermann F.S.,Gnad F.,Olsen J.V.,Hornberger R.,Greff Z.,Keri G.,Mann M.,Daub H.
Large-scale proteomics analysis of the human kinome.
Mol. Cell. Proteomics
8
1751-1764
2009
99301
Boehmer C.,Sopjani M.,Klaus F.,Lindner R.,Laufer J.,Jeyaraj S.,Lang F.,Palmada M.
The serum and glucocorticoid inducible kinases SGK1-3 stimulate the neutral amino acid transporter SLC6A19.
Cell. Physiol. Biochem.
25
723-732
2010
99302
Lu M.,Wang J.,Jones K.T.,Ives H.E.,Feldman M.E.,Yao L.J.,Shokat K.M.,Ashrafi K.,Pearce D.
mTOR complex-2 activates ENaC by phosphorylating SGK1.
J. Am. Soc. Nephrol.
21
811-818
2010
99303
Wiemuth D.,Lott J.S.,Ly K.,Ke Y.,Teesdale-Spittle P.,Snyder P.M.,McDonald F.J.
Interaction of serum- and glucocorticoid regulated kinase 1 (SGK1) with the WW-domains of Nedd4-2 is required for epithelial sodium channel regulation.
PLoS ONE
5
0-0
2010
99304
Olsen J.V.,Vermeulen M.,Santamaria A.,Kumar C.,Miller M.L.,Jensen L.J.,Gnad F.,Cox J.,Jensen T.S.,Nigg E.A.,Brunak S.,Mann M.
Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
Sci. Signal.
3
0-0
2010
99305
He P.,Lee S.J.,Lin S.,Seidler U.,Lang F.,Fejes-Toth G.,Naray-Fejes-Toth A.,Yun C.C.
Serum- and glucocorticoid-induced kinase 3 in recycling endosomes mediates acute activation of Na+/H+ exchanger NHE3 by glucocorticoids.
Mol. Biol. Cell
22
3812-3825
2011
99306
Firestone G.L.,Giampaolo J.R.,O'Keeffe B.A.
Stimulus-dependent regulation of serum and glucocorticoid inducible protein kinase (SGK) transcription, subcellular localization and enzymatic activity.
Cell. Physiol. Biochem.
13
1-12
2003
99307
Loffing J.,Flores S.Y.,Staub O.
Sgk kinases and their role in epithelial transport.
Annu. Rev. Physiol.
68
461-490
2006
99308
Bruhn M.A.,Pearson R.B.,Hannan R.D.,Sheppard K.E.
Second AKT: the rise of SGK in cancer signalling.
Growth Factors
28
394-408
2010
99309
Lang F.,Strutz-Seebohm N.,Seebohm G.,Lang U.E.
Significance of SGK1 in the regulation of neuronal function.
J. Physiol. (Lond.)
588
3349-3354
2010
99310
Zhao B.,Lehr R.,Smallwood A.M.,Ho T.F.,Maley K.,Randall T.,Head M.S.,Koretke K.K.,Schnackenberg C.G.
Crystal structure of the kinase domain of serum and glucocorticoid-regulated kinase 1 in complex with AMP PNP.
Protein Sci.
16
2761-2769
2007
99311
Greenman C.,Stephens P.,Smith R.,Dalgliesh G.L.,Hunter C.,Bignell G.,Davies H.,Teague J.,Butler A.,Stevens C.,Edkins S.,O'Meara S.,Vastrik I.,Schmidt E.E.,Avis T.,Barthorpe S.,Bhamra G.,Buck G.,Choudhury B.,Clements J.,Cole J.,Dicks E.,Forbes S.,Gray K.,Halliday K.,Harrison R.,Hills K.,Hinton J.,Jenkinson A.,Jones D.,Menzies A.,Mironenko T.,Perry J.,Raine K.,Richardson D.,Shepherd R.,Small A.,Tofts C.,Varian J.,Webb T.,West S.,Widaa S.,Yates A.,Cahill D.P.,Louis D.N.,Goldstraw P.,Nicholson A.G.,Brasseur F.,Looijenga L.,Weber B.L.,Chiew Y.-E.,DeFazio A.,Greaves M.F.,Green A.R.,Campbell P.,Birney E.,Easton D.F.,Chenevix-Trench G.,Tan M.-H.,Khoo S.K.,Teh B.T.,Yuen S.T.,Leung S.Y.,Wooster R.,Futreal P.A.,Stratton M.R.
Patterns of somatic mutation in human cancer genomes.
Nature
446
153-158
2007