Any feedback?
Please rate this page
(sequences.php)
(0/150)

BRENDA support

Sequence of FAA28_MYCTU

EC Number:6.2.1.49

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
long-chain fatty acid adenylyltransferase FadD28
P9WQ59
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
580
62641
Reaction
a long-chain acyl-adenylate ester + holo-[mycocerosate synthase] = AMP + a long-chain acyl-[mycocerosate synthase]
Other sequences found for EC No. 6.2.1.49

General information:

Sequence
show sequence in fasta format
  0 MSVRSLPAAL RACARLQPHD PAFTFMDYEQ DWDGVAITLT WSQLYRRTLN VAQELSRCGS
 60 TGDRVVISAP QGLEYVVAFL GALQAGRIAV PLSVPQGGVT DERSDSVLSD SSPVAILTTS
120 SAVDDVVQHV ARRPGESPPS IIEVDLLDLD APNGYTFKED EYPSTAYLQY TSGSTRTPAG
180 VVMSHQNVRV NFEQLMSGYF ADTDGIPPPN SALVSWLPFY HDMGLVIGIC APILGGYPAV
240 LTSPVSFLQR PARWMHLMAS DFHAFSAAPN FAFELAARRT TDDDMAGRDL GNILTILSGS
300 ERVQAATIKR FADRFARFNL QERVIRPSYG LAEATVYVAT SKPGQPPETV DFDTESLSAG
360 HAKPCAGGGA TSLISYMLPR SPIVRIVDSD TCIECPDGTV GEIWVHGDNV ANGYWQKPDE
420 SERTFGGKIV TPSPGTPEGP WLRTGDSGFV TDGKMFIIGR IKDLLIVYGR NHSPDDIEAT
480 IQEITRGRCA AISVPGDRST EKLVAIIELK KRGDSDQDAM ARLGAIKREV TSALSSSHGL
540 SVADLVLVAP GSIPITTSGK VRRGACVEQY RQDQFARLDA
Download this sequence
in fasta format
Download all sequences for 6.2.1.49
in fasta format
in csv (Excel, OpenOffice) format
Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
1056817
Cole S.T.,Brosch R.,Parkhill J.,Garnier T.,Churcher C.M.,Harris D.E.,Gordon S.V.,Eiglmeier K.,Gas S.,Barry C.E. III,Tekaia F.,Badcock K.,Basham D.,Brown D.,Chillingworth T.,Connor R.,Davies R.M.,Devlin K.,Feltwell T.,Gentles S.,Hamlin N.,Holroyd S.,Hornsby T.,Jagels K.,Krogh A.,McLean J.,Moule S.,Murphy L.D.,Oliver S.,Osborne J.,Quail M.A.,Rajandream M.A.,Rogers J.,Rutter S.,Seeger K.,Skelton S.,Squares S.,Squares R.,Sulston J.E.,Taylor K.,Whitehead S.,Barrell B.G.
Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.
Nature
393
537-544
1998
1056818
Cox J.S.,Chen B.,McNeil M.,Jacobs W.R. Jr.
Complex lipid determines tissue-specific replication of Mycobacterium tuberculosis in mice.
Nature
402
79-83
1999
1056819
Camacho L.R.,Constant P.,Raynaud C.,Laneelle M.A.,Triccas J.A.,Gicquel B.,Daffe M.,Guilhot C.
Analysis of the phthiocerol dimycocerosate locus of Mycobacterium tuberculosis. Evidence that this lipid is involved in the cell wall permeability barrier.
J. Biol. Chem.
276
19845-19854
2001
1056820
Trivedi O.A.,Arora P.,Sridharan V.,Tickoo R.,Mohanty D.,Gokhale R.S.
Enzymic activation and transfer of fatty acids as acyl-adenylates in mycobacteria.
Nature
428
441-445
2004
1056821
Raman K.,Yeturu K.,Chandra N.
targetTB: a target identification pipeline for Mycobacterium tuberculosis through an interactome, reactome and genome-scale structural analysis.
BMC Syst. Biol.
2
109-109
2008
1056822
Brodin P.,Poquet Y.,Levillain F.,Peguillet I.,Larrouy-Maumus G.,Gilleron M.,Ewann F.,Christophe T.,Fenistein D.,Jang J.,Jang M.S.,Park S.J.,Rauzier J.,Carralot J.P.,Shrimpton R.,Genovesio A.,Gonzalo-Asensio J.A.,Puzo G.,Martin C.,Brosch R.,Stewart G.R.,Gicquel B.,Neyrolles O.
High content phenotypic cell-based visual screen identifies Mycobacterium tuberculosis acyltrehalose-containing glycolipids involved in phagosome remodeling.
PLoS Pathog.
6
0-0
2010
1056823
Kelkar D.S.,Kumar D.,Kumar P.,Balakrishnan L.,Muthusamy B.,Yadav A.K.,Shrivastava P.,Marimuthu A.,Anand S.,Sundaram H.,Kingsbury R.,Harsha H.C.,Nair B.,Prasad T.S.,Chauhan D.S.,Katoch K.,Katoch V.M.,Kumar P.,Chaerkady R.,Ramachandran S.,Dash D.,Pandey A.
Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.
Mol. Cell. Proteomics
10
0-0
2011
1056824
Menendez-Bravo S.,Comba S.,Sabatini M.,Arabolaza A.,Gramajo H.
Expanding the chemical diversity of natural esters by engineering a polyketide-derived pathway into Escherichia coli.
Metab. Eng.
24
97-106
2014
1056825
Goyal A.,Yousuf M.,Rajakumara E.,Arora P.,Gokhale R.S.,Sankaranarayanan R.
Crystallization and preliminary X-ray crystallographic studies of the N-terminal domain of FadD28, a fatty-acyl AMP ligase from Mycobacterium tuberculosis.
Acta Crystallogr. F
62
350-352
2006
1056826
Arora P.,Goyal A.,Natarajan V.T.,Rajakumara E.,Verma P.,Gupta R.,Yousuf M.,Trivedi O.A.,Mohanty D.,Tyagi A.,Sankaranarayanan R.,Gokhale R.S.
Mechanistic and functional insights into fatty acid activation in Mycobacterium tuberculosis.
Nat. Chem. Biol.
5
166-173
2009
1056827
Goyal A.,Verma P.,Anandhakrishnan M.,Gokhale R.S.,Sankaranarayanan R.
Molecular basis of the functional divergence of fatty acyl-AMP ligase biosynthetic enzymes of Mycobacterium tuberculosis.
J. Mol. Biol.
416
221-238
2012