Sequence of DBF2_YEAST
EC Number:2.7.11.1
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
non-specific serine/threonine protein kinase
P22204
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
572
66148
Reaction
ATP + a [protein]-(L-serine/L-threonine) = ADP + a [protein]-(L-serine/L-threonine) phosphate
Other sequences found for EC No. 2.7.11.1
General information:
Sequence
0 MLSKSEKNVD LLAGNMSNLS FDGHGTPGGT GLFPNQNITK RRTRPAGIND SPSPVKPSFF
60 PYEDTSNMDI DEVSQPDMDV SNSPKKLPPK FYERATSNKT QRVVSVCKMY FLEHYCDMFD
120 YVISRRQRTK QVLEYLQQQS QLPNSDQIKL NEEWSSYLQR EHQVLRKRRL KPKNRDFEMI
180 TQVGQGGYGQ VYLARKKDTK EVCALKILNK KLLFKLNETK HVLTERDILT TTRSEWLVKL
240 LYAFQDLQSL YLAMEFVPGG DFRTLLINTR CLKSGHARFY ISEMFCAVNA LHDLGYTHRD
300 LKPENFLIDA KGHIKLTDFG LAAGTISNER IESMKIRLEK IKDLEFPAFT EKSIEDRRKM
360 YNQLREKEIN YANSMVGSPD YMALEVLEGK KYDFTVDYWS LGCMLFESLV GYTPFSGSST
420 NETYDNLRRW KQTLRRPRQS DGRAAFSDRT WDLITRLIAD PINRLRSFEH VKRMSYFADI
480 NFSTLRSMIP PFTPQLDSET DAGYFDDFTS EADMAKYADV FKRQDKLTAM VDDSAVSSKL
540 VGFTFRHRNG KQGSSGILFN GLEHSDPFST FY
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
1048005
Johnston L.H.,Eberly S.L.,Chapman J.W.,Araki H.,Sugino A.
The product of the Saccharomyces cerevisiae cell cycle gene DBF2 has homology with protein kinases and is periodically expressed in the cell cycle.
Mol. Cell. Biol.
10
1358-1366
1990
1048006
Toyn J.H.,Araki H.,Sugino A.,Johnston L.H.
The cell-cycle-regulated budding yeast gene DBF2, encoding a putative protein kinase, has a homologue that is not under cell-cycle control.
Gene
104
63-70
1991
1048007
Tettelin H.,Agostoni-Carbone M.L.,Albermann K.,Albers M.,Arroyo J.,Backes U.,Barreiros T.,Bertani I.,Bjourson A.J.,Brueckner M.,Bruschi C.V.,Carignani G.,Castagnoli L.,Cerdan E.,Clemente M.L.,Coblenz A.,Coglievina M.,Coissac E.,Defoor E.,Del Bino S.,Delius H.,Delneri D.,de Wergifosse P.,Dujon B.,Durand P.,Entian K.-D.,Eraso P.,Escribano V.,Fabiani L.,Fartmann B.,Feroli F.,Feuermann M.,Frontali L.,Garcia-Gonzalez M.,Garcia-Saez M.I.,Goffeau A.,Guerreiro P.,Hani J.,Hansen M.,Hebling U.,Hernandez K.,Heumann K.,Hilger F.,Hofmann B.,Indge K.J.,James C.M.,Klima R.,Koetter P.,Kramer B.,Kramer W.,Lauquin G.,Leuther H.,Louis E.J.,Maillier E.,Marconi A.,Martegani E.,Mazon M.J.,Mazzoni C.,McReynolds A.D.K.,Melchioretto P.,Mewes H.-W.,Minenkova O.,Mueller-Auer S.,Nawrocki A.,Netter P.,Neu R.,Nombela C.,Oliver S.G.,Panzeri L.,Paoluzi S.,Plevani P.,Portetelle D.,Portillo F.,Potier S.,Purnelle B.,Rieger M.,Riles L.,Rinaldi T.,Robben J.,Rodrigues-Pousada C.,Rodriguez-Belmonte E.,Rodriguez-Torres A.M.,Rose M.,Ruzzi M.,Saliola M.,Sanchez-Perez M.,Schaefer B.,Schaefer M.,Scharfe M.,Schmidheini T.,Schreer A.,Skala J.,Souciet J.-L.,Steensma H.Y.,Talla E.,Thierry A.,Vandenbol M.,van der Aart Q.J.M.,Van Dyck L.,Vanoni M.,Verhasselt P.,Voet M.,Volckaert G.,Wambutt R.,Watson M.D.,Weber N.,Wedler E.,Wedler H.,Wipfli P.,Wolf K.,Wright L.F.,Zaccaria P.,Zimmermann M.,Zollner A.,Kleine K.
The nucleotide sequence of Saccharomyces cerevisiae chromosome VII.
Nature
387
81-84
1997
1048008
Engel S.R.,Dietrich F.S.,Fisk D.G.,Binkley G.,Balakrishnan R.,Costanzo M.C.,Dwight S.S.,Hitz B.C.,Karra K.,Nash R.S.,Weng S.,Wong E.D.,Lloyd P.,Skrzypek M.S.,Miyasato S.R.,Simison M.,Cherry J.M.
The reference genome sequence of Saccharomyces cerevisiae: Then and now.
G3 (Bethesda)
4
389-398
2014
1048009
Toyn J.H.,Johnston L.H.
The Dbf2 and Dbf20 protein kinases of budding yeast are activated after the metaphase to anaphase cell cycle transition.
EMBO J.
13
1103-1113
1994
1048010
Komarnitsky S.I.,Chiang Y.-C.,Luca F.C.,Chen J.,Toyn J.H.,Winey M.,Johnston L.H.,Denis C.L.
DBF2 protein kinase binds to and acts through the cell cycle-regulated MOB1 protein.
Mol. Cell. Biol.
18
2100-2107
1998
1048011
Grandin N.,de Almeida A.,Charbonneau M.
The Cdc14 phosphatase is functionally associated with the Dbf2 protein kinase in Saccharomyces cerevisiae.
Mol. Gen. Genet.
258
104-116
1998
1048012
Fesquet D.,Fitzpatrick P.J.,Johnson A.L.,Kramer K.M.,Toyn J.H.,Johnston L.H.
A Bub2p-dependent spindle checkpoint pathway regulates the Dbf2p kinase in budding yeast.
EMBO J.
18
2424-2434
1999
1048013
Frenz L.M.,Lee S.E.,Fesquet D.,Johnston L.H.
The budding yeast Dbf2 protein kinase localises to the centrosome and moves to the bud neck in late mitosis.
J. Cell Sci.
113
3399-3408
2000
1048014
Lee S.E.,Frenz L.M.,Wells N.J.,Johnson A.L.,Johnston L.H.
Order of function of the budding-yeast mitotic exit-network proteins Tem1, Cdc15, Mob1, Dbf2, and Cdc5.
Curr. Biol.
11
784-788
2001
1048015
Yoshida S.,Toh-e A.
Regulation of the localization of Dbf2 and Mob1 during cell division of Saccharomyces cerevisiae.
Genes Genet. Syst.
76
141-147
2001
1048016
Visintin R.,Amon A.
Regulation of the mitotic exit protein kinases Cdc15 and Dbf2.
Mol. Biol. Cell
12
2961-2974
2001
1048017
Mah A.S.,Jang J.,Deshaies R.J.
Protein kinase Cdc15 activates the Dbf2-Mob1 kinase complex.
Proc. Natl. Acad. Sci. U.S.A.
98
7325-7330
2001
1048018
Visintin R.,Stegmeier F.,Amon A.
The role of the polo kinase Cdc5 in controlling Cdc14 localization.
Mol. Biol. Cell
14
4486-4498
2003
1048019
Hwa Lim H.,Yeong F.M.,Surana U.
Inactivation of mitotic kinase triggers translocation of MEN components to mother-daughter neck in yeast.
Mol. Biol. Cell
14
4734-4743
2003
1048020
Bardin A.J.,Boselli M.G.,Amon A.
Mitotic exit regulation through distinct domains within the protein kinase Cdc15.
Mol. Cell. Biol.
23
5018-5030
2003
1048021
Ghaemmaghami S.,Huh W.-K.,Bower K.,Howson R.W.,Belle A.,Dephoure N.,O'Shea E.K.,Weissman J.S.
Global analysis of protein expression in yeast.
Nature
425
737-741
2003
1048022
Mah A.S.,Elia A.E.,Devgan G.,Ptacek J.,Schutkowski M.,Snyder M.,Yaffe M.B.,Deshaies R.J.
Substrate specificity analysis of protein kinase complex Dbf2-Mob1 by peptide library and proteome array screening.
BMC Biochem.
6
22-22
2005
1048023
Stoepel J.,Ottey M.A.,Kurischko C.,Hieter P.,Luca F.C.
The mitotic exit network Mob1p-Dbf2p kinase complex localizes to the nucleus and regulates passenger protein localization.
Mol. Biol. Cell
16
5465-5479
2005
1048024
Makrantoni V.,Dennison P.,Stark M.J.,Coote P.J.
A novel role for the yeast protein kinase Dbf2p in vacuolar H+-ATPase function and sorbic acid stress tolerance.
Microbiology
153
4016-4026
2007
1048025
Albuquerque C.P.,Smolka M.B.,Payne S.H.,Bafna V.,Eng J.,Zhou H.
A multidimensional chromatography technology for in-depth phosphoproteome analysis.
Mol. Cell. Proteomics
7
1389-1396
2008
1048026
Mohl D.A.,Huddleston M.J.,Collingwood T.S.,Annan R.S.,Deshaies R.J.
Dbf2-Mob1 drives relocalization of protein phosphatase Cdc14 to the cytoplasm during exit from mitosis.
J. Cell Biol.
184
527-539
2009
1048027
Holt L.J.,Tuch B.B.,Villen J.,Johnson A.D.,Gygi S.P.,Morgan D.O.
Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.
Science
325
1682-1686
2009
1048028
Konig C.,Maekawa H.,Schiebel E.
Mutual regulation of cyclin-dependent kinase and the mitotic exit network.
J. Cell Biol.
188
351-368
2010
1048029
Meitinger F.,Petrova B.,Lombardi I.M.,Bertazzi D.T.,Hub B.,Zentgraf H.,Pereira G.
Targeted localization of Inn1, Cyk3 and Chs2 by the mitotic-exit network regulates cytokinesis in budding yeast.
J. Cell Sci.
123
1851-1861
2010
1048030
Trcek T.,Larson D.R.,Moldon A.,Query C.C.,Singer R.H.
Single-molecule mRNA decay measurements reveal promoter- regulated mRNA stability in yeast.
Cell
147
1484-1497
2011
1048031
Oh Y.,Chang K.J.,Orlean P.,Wloka C.,Deshaies R.,Bi E.
Mitotic exit kinase Dbf2 directly phosphorylates chitin synthase Chs2 to regulate cytokinesis in budding yeast.
Mol. Biol. Cell
23
2445-2456
2012
1048032
Meitinger F.,Palani S.,Hub B.,Pereira G.
Dual function of the NDR-kinase Dbf2 in the regulation of the F-BAR protein Hof1 during cytokinesis.
Mol. Biol. Cell
24
1290-1304
2013
