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Sequence of TSUKU_STRT9

EC Number:4.2.3.159

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
tsukubadiene synthase
I2N045
Streptomyces tsukubensis (strain DSM 42081 / NBRC 108919 / NRRL 18488 / 9993)
332
37389
Reaction
geranylgeranyl diphosphate = tsukubadiene + diphosphate
Other sequences found for EC No. 4.2.3.159

General information:

Sequence
show sequence in fasta format
  0 MIEVPPFWCP LPIAIHPAAD QAEKDARAWA ERYGVRLRIA DQVQPGRLGA YWAPHGTYEG
 60 MLAVGCWNFW AFAFDDHLDE PLPLDVPVTT SLVQQAVDIP SPPITDDPWA AGAQAVFNMF
120 RDLATPTQVR YCADNHRRWL HGACWRHSNH VNRRLPPLAE YIPLRMQDAA AQATCLIAVL
180 IGSDISVPEQ EMDSPRVRAL LETASWTATI DSDLHSFQLE DTQRPVSQHI VSVLMHERGI
240 GVDEALRQSV ALRDRFMTRF LHLQQECART GSSELARFAH TLGYVISGYL QWAVDTSRYG
300 QTEATFSFTD TPRDDTPEPP PGIPSVEWLW TL
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
1009834
Barreiro C.,Prieto C.,Sola-Landa A.,Solera E.,Martinez-Castro M.,Perez-Redondo R.,Garcia-Estrada C.,Aparicio J.F.,Fernandez-Martinez L.T.,Santos-Aberturas J.,Salehi-Najafabadi Z.,Rodriguez-Garcia A.,Tauch A.,Martin J.F.
Draft genome of Streptomyces tsukubaensis NRRL 18488, the producer of the clinically important immunosuppressant tacrolimus (FK506).
J. Bacteriol.
194
3756-3757
2012
1009835
Yamada Y.,Arima S.,Nagamitsu T.,Johmoto K.,Uekusa H.,Eguchi T.,Shin-ya K.,Cane D.E.,Ikeda H.
Novel terpenes generated by heterologous expression of bacterial terpene synthase genes in an engineered Streptomyces host.
J. Antibiot.
68
385-394
2015
1009836
Rabe P.,Rinkel J.,Dolja E.,Schmitz T.,Nubbemeyer B.,Luu T.H.,Dickschat J.S.
Mechanistic investigations of two bacterial diterpene cyclases: spiroviolene synthase and tsukubadiene synthase.
Angew. Chem. Int. Ed.
56
2776-2779
2017