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Sequence of RMLC_MYCTU

EC Number:5.1.3.13

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
dTDP-4-dehydrorhamnose 3,5-epimerase
P9WH11
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
202
22314
Reaction
dTDP-4-dehydro-6-deoxy-alpha-D-glucose = dTDP-4-dehydro-beta-L-rhamnose
Other sequences found for EC No. 5.1.3.13

General information:

Sequence
show sequence in fasta format
  0 MKARELDVPG AWEITPTIHV DSRGLFFEWL TDHGFRAFAG HSLDVRQVNC SVSSAGVLRG
 60 LHFAQLPPSQ AKYVTCVSGS VFDVVVDIRE GSPTFGRWDS VLLDDQDRRT IYVSEGLAHG
120 FLALQDNSTV MYLCSAEYNP QREHTICATD PTLAVDWPLV DGAAPSLSDR DAAAPSFEDV
180 RASGLLPRWE QTQRFIGEMR GT
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
987199
Cole S.T.,Brosch R.,Parkhill J.,Garnier T.,Churcher C.M.,Harris D.E.,Gordon S.V.,Eiglmeier K.,Gas S.,Barry C.E. III,Tekaia F.,Badcock K.,Basham D.,Brown D.,Chillingworth T.,Connor R.,Davies R.M.,Devlin K.,Feltwell T.,Gentles S.,Hamlin N.,Holroyd S.,Hornsby T.,Jagels K.,Krogh A.,McLean J.,Moule S.,Murphy L.D.,Oliver S.,Osborne J.,Quail M.A.,Rajandream M.A.,Rogers J.,Rutter S.,Seeger K.,Skelton S.,Squares S.,Squares R.,Sulston J.E.,Taylor K.,Whitehead S.,Barrell B.G.
Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.
Nature
393
537-544
1998
987200
Li W.,Xin Y.,McNeil M.R.,Ma Y.
rmlB and rmlC genes are essential for growth of mycobacteria.
Biochem. Biophys. Res. Commun.
342
170-178
2006
987201
Raman K.,Yeturu K.,Chandra N.
targetTB: a target identification pipeline for Mycobacterium tuberculosis through an interactome, reactome and genome-scale structural analysis.
BMC Syst. Biol.
2
109-109
2008
987202
Kelkar D.S.,Kumar D.,Kumar P.,Balakrishnan L.,Muthusamy B.,Yadav A.K.,Shrivastava P.,Marimuthu A.,Anand S.,Sundaram H.,Kingsbury R.,Harsha H.C.,Nair B.,Prasad T.S.,Chauhan D.S.,Katoch K.,Katoch V.M.,Kumar P.,Chaerkady R.,Ramachandran S.,Dash D.,Pandey A.
Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.
Mol. Cell. Proteomics
10
0-0
2011
987203
Babaoglu K.,Page M.A.,Jones V.C.,McNeil M.R.,Dong C.,Naismith J.H.,Lee R.E.
Novel inhibitors of an emerging target in Mycobacterium tuberculosis; substituted thiazolidinones as inhibitors of dTDP-rhamnose synthesis.
Bioorg. Med. Chem. Lett.
13
3227-3230
2003
987204
Kantardjieff K.A.,Kim C.Y.,Naranjo C.,Waldo G.S.,Lekin T.,Segelke B.W.,Zemla A.,Park M.S.,Terwilliger T.C.,Rupp B.
Mycobacterium tuberculosis RmlC epimerase (Rv3465): a promising drug-target structure in the rhamnose pathway.
Acta Crystallogr. D
60
895-902
2004
987205
Dong C.,Major L.L.,Srikannathasan V.,Errey J.C.,Giraud M.F.,Lam J.S.,Graninger M.,Messner P.,McNeil M.R.,Field R.A.,Whitfield C.,Naismith J.H.
RmlC, a C3' and C5' carbohydrate epimerase, appears to operate via an intermediate with an unusual twist boat conformation.
J. Mol. Biol.
365
146-159
2007