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Sequence of RAP2B_HUMAN

EC Number:3.6.5.2

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
small monomeric GTPase
P61225
Homo sapiens
183
20504
Reaction
GTP + H2O = GDP + phosphate
Other sequences found for EC No. 3.6.5.2

General information:

Sequence
show sequence in fasta format
  0 MREYKVVVLG SGGVGKSALT VQFVTGSFIE KYDPTIEDFY RKEIEVDSSP SVLEILDTAG
 60 TEQFASMRDL YIKNGQGFIL VYSLVNQQSF QDIKPMRDQI IRVKRYERVP MILVGNKVDL
120 EGEREVSYGE GKALAEEWSC PFMETSAKNK ASVDELFAEI VRQMNYAAQP NGDEGCCSAC
180 VIL
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
979409
Farrell F.X.,Ohmstede C.A.,Reep B.R.,Lapetina E.G.
cDNA sequence of a new ras-related gene (rap2b) isolated from human platelets with sequence homology to rap2.
Nucleic Acids Res.
18
4281-4281
1990
979410
Ohmstede C.A.,Farrell F.X.,Reep B.R.,Clemetson K.J.,Lapetina E.G.
RAP2B: a RAS-related GTP-binding protein from platelets.
Proc. Natl. Acad. Sci. U.S.A.
87
6527-6531
1990
979412
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Genome Res.
14
2121-2127
2004
979413
Farrell F.X.,Yamamoto K.,Lapetina E.G.
Prenyl group identification of rap2 proteins: a ras superfamily member other than ras that is farnesylated.
Biochem. J.
289
349-355
1993
979414
Evellin S.,Nolte J.,Tysack K.,vom Dorp F.,Thiel M.,Weernink P.A.O.,Jakobs K.H.,Webb E.J.,Lomasney J.W.,Schmidt M.
Stimulation of phospholipase C-epsilon by the M3 muscarinic acetylcholine receptor mediated by cyclic AMP and the GTPase Rap2B.
J. Biol. Chem.
277
16805-16813
2002
979415
Song C.,Satoh T.,Edamatsu H.,Wu D.,Tadano M.,Gao X.,Kataoka T.
Differential roles of Ras and Rap1 in growth factor-dependent activation of phospholipase C epsilon.
Oncogene
21
8105-8113
2002
979416
Stope M.B.,Vom Dorp F.,Szatkowski D.,Boehm A.,Keiper M.,Nolte J.,Oude Weernink P.A.,Rosskopf D.,Evellin S.,Jakobs K.H.,Schmidt M.
Rap2B-dependent stimulation of phospholipase C-epsilon by epidermal growth factor receptor mediated by c-Src phosphorylation of RasGRP3.
Mol. Cell. Biol.
24
4664-4676
2004
979417
Greco F.,Ciana A.,Pietra D.,Balduini C.,Minetti G.,Torti M.
Rap2, but not Rap1 GTPase is expressed in human red blood cells and is involved in vesiculation.
Biochim. Biophys. Acta
1763
330-335
2006
979418
Yang H.,Sasaki T.,Minoshima S.,Shimizu N.
Identification of three novel proteins (SGSM1, 2, 3) which modulate small G protein (RAP and RAB)-mediated signaling pathway.
Genomics
90
249-260
2007
979419
Burkard T.R.,Planyavsky M.,Kaupe I.,Breitwieser F.P.,Buerckstuemmer T.,Bennett K.L.,Superti-Furga G.,Colinge J.
Initial characterization of the human central proteome.
BMC Syst. Biol.
5
17-17
2011
979420
Vaca Jacome A.S.,Rabilloud T.,Schaeffer-Reiss C.,Rompais M.,Ayoub D.,Lane L.,Bairoch A.,Van Dorsselaer A.,Carapito C.
N-terminome analysis of the human mitochondrial proteome.
Proteomics
15
2519-2524
2015