Sequence of RNT1_ASPOR

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
ribonuclease T1
P00651
Aspergillus oryzae (strain ATCC 42149 / RIB 40)
130
13960
Reaction
two-stage endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotides ending in Gp with 2',3'-cyclic phosphate intermediates
Sequences with same EC No.
Sequence
show sequence in fasta format
  0 MMYSKLLTLT TLLLPTALAL PSLVERACDY TCGSNCYSSS DVSTAQAAGY QLHEDGETVG
 60 SNSYPHKYNN YEGFDFSVSS PYYEWPILSS GDVYSGGSPG ADRVVFNENN QLAGVITHTG
120 ASGNNFVECT
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
87327
Fujii T.,Yamaoka H.,Gomi K.,Kitamoto K.,Kumagai C.
Cloning and nucleotide sequence of the ribonuclease T1 gene (rntA) from Aspergillus oryzae and its expression in Saccharomyces cerevisiae and Aspergillus oryzae.
Biosci. Biotechnol. Biochem.
59
1869-1874
1995
87328
Machida M.,Asai K.,Sano M.,Tanaka T.,Kumagai T.,Terai G.,Kusumoto K.,Arima T.,Akita O.,Kashiwagi Y.,Abe K.,Gomi K.,Horiuchi H.,Kitamoto K.,Kobayashi T.,Takeuchi M.,Denning D.W.,Galagan J.E.,Nierman W.C.,Yu J.,Archer D.B.,Bennett J.W.,Bhatnagar D.,Cleveland T.E.,Fedorova N.D.,Gotoh O.,Horikawa H.,Hosoyama A.,Ichinomiya M.,Igarashi R.,Iwashita K.,Juvvadi P.R.,Kato M.,Kato Y.,Kin T.,Kokubun A.,Maeda H.,Maeyama N.,Maruyama J.,Nagasaki H.,Nakajima T.,Oda K.,Okada K.,Paulsen I.,Sakamoto K.,Sawano T.,Takahashi M.,Takase K.,Terabayashi Y.,Wortman J.R.,Yamada O.,Yamagata Y.,Anazawa H.,Hata Y.,Koide Y.,Komori T.,Koyama Y.,Minetoki T.,Suharnan S.,Tanaka A.,Isono K.,Kuhara S.,Ogasawara N.,Kikuchi H.
Genome sequencing and analysis of Aspergillus oryzae.
Nature
438
1157-1161
2005
87329
Takahashi K.
The structure and function of ribonuclease T1. XVII. Isolation and amino acid sequences of papain and subtilisin peptides from ribonuclease T1 -- the complete covalent structure of ribonuclease T1.
J. Biochem.
70
945-960
1971
87330
Takahashi K.
A revision and confirmation of the amino acid sequence of ribonuclease T1.
J. Biochem.
98
815-817
1985
87331
Takahashi K.,Stein W.H.,Moore S.
The identification of a glutamic acid residue as part of the active site of ribonuclease T-1.
J. Biol. Chem.
242
4682-4690
1967
87332
Takahashi K.
The structure and function of ribonuclease T1. XII. Further studies on rose bengal-catalyzed photooxidation of ribonuclease T1 -- identification of a critical histidine residue.
J. Biochem.
69
331-338
1971
87333
Arni R.,Heinemann U.,Tokuoka R.,Saenger W.
Three-dimensional structure of the ribonuclease T1 2'-GMP complex at 1.9-A resolution.
J. Biol. Chem.
263
15358-15368
1988
87334
Koepke J.,Maslowska M.,Heinemann U.,Saenger W.
Three-dimensional structure of ribonuclease T1 complexed with guanylyl-2',5'-guanosine at 1.8-A resolution.
J. Mol. Biol.
206
475-488
1989
87335
Hakoshima T.,Itoh T.,Tomita K.,Goda K.,Nishikawa S.,Morioka H.,Uesugi S.,Ohtsuka E.,Ikehara M.
Three-dimensional structure of a mutant ribonuclease T1 (Y45W) complexed with non-cognizable ribonucleotide, 2'AMP, and its comparison with a specific complex with 2'GMP.
J. Mol. Biol.
223
1013-1028
1992
87336
Zegers I.,Loris R.,Dehollander G.,Fattah Haikal A.,Poortmans F.,Steyaert J.,Wyns L.
Hydrolysis of a slow cyclic thiophosphate substrate of RNase T1 analyzed by time-resolved crystallography.
Nat. Struct. Biol.
5
280-283
1998
87337
Arni R.K.,Watanabe L.,Ward R.J.,Kreitman R.J.,Kumar K.,Walz F.G. Jr.
Three-dimensional structure of ribonuclease T1 complexed with an isosteric phosphonate substrate analogue of GpU: alternate substrate binding modes and catalysis.
Biochemistry
38
2452-2461
1999
87338
Langhorst U.,Loris R.,Denisov V.P.,Doumen J.,Roose P.,Maes D.,Halle B.,Steyaert J.
Dissection of the structural and functional role of a conserved hydration site in RNase T1.
Protein Sci.
8
722-730
1999
87339
Mignon P.,Steyaert J.,Loris R.,Geerlings P.,Loverix S.
A nucleophile activation dyad in ribonucleases. A combined X-ray crystallographic/ab initio quantum chemical study.
J. Biol. Chem.
277
36770-36774
2002
87340
Hoffmann E.,Rueterjans H.
Two-dimensional 1H-NMR investigation of ribonuclease T1. Resonance assignments, secondary and low-resolution tertiary structures of ribonuclease T1.
Eur. J. Biochem.
177
539-560
1988