Sequence of MELA_LACAC
EC Number:3.2.1.22
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
alpha-galactosidase
G1UB44
Lactobacillus acidophilus (strain ATCC 700396 / NCK56 / N2 / NCFM)
732
84478
Reaction
alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide + H2O = D-galactose + beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide
Other sequences found for EC No. 3.2.1.22
General information:
Sequence
0 MTSNLIKFDD QNKVFHLHNK QISYLLSIED GGTLSHLYFG GAVKNYNNQL KYPRLDRGFS
60 GNLPESLDRT FSRDSLPKEY SSAGEMDFHT PATIVRNPDG SNALFLAYKS YKIEDGKPDL
120 KGLPHSWTKE DDEAQTLIVT LEDKVSKLEY DLLYTIYRDR PVIVRSVQVH NHGEEAVYLE
180 KVASMQMDYV DKDFEVITLP GAHANERRVQ RENIGQGIKV FSSYRGTSSH QMNPFMALVD
240 HDTNEFMGEA YGFALAYSGN HKFEVERDQF GQIHVNTGIN DYNFKWKLNP NEEFQTPEVL
300 MVYSDQGLNK MSQAFHSLIH ERIMRSKFKD QIRPVLVNNW EATYFDFNED KLKTIVDKAK
360 KLGLEMFVLD DGWFGHRDDD NSSLGDWKVY KKKFPNGLGH FADYVHEQGL KFGLWFEPEM
420 ISYESNLYKE HPDYLMHVPG RKPCPSRNQY VLELGRKEVR DNIFEQMVKI LDSKKIDYIK
480 WDMNRSLSDI YESDLPADQQ GEAYHRYVLG YYDLLNKLVT RYPDILFEGC SGGGGRFDVG
540 QAYYTPQIWA SDNTDAIERL KIQYGTSLVY PQSMMTSHVS VSPNEQNGRI TPFNTRGAVA
600 MWGDLGYELD LTKMSDEESD QVVKQVTEYK KIREVTQFGT LYRLKASASN QCAWMMVDSN
660 KNEAVVTVVN VMAHAQPYCT KTKLAGLDPD KRYKNLETDE VFGGDELMHL GFYDPIERGD
720 FKAKMYHFKA IN
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
953147
Barrangou R.,Altermann E.,Hutkins R.,Cano R.,Klaenhammer T.R.
Functional and comparative genomic analyses of an operon involved in fructooligosaccharide utilization by Lactobacillus acidophilus.
Proc. Natl. Acad. Sci. U.S.A.
100
8957-8962
2003
953148
Altermann E.,Russell W.M.,Azcarate-Peril M.A.,Barrangou R.,Buck B.L.,McAuliffe O.,Souther N.,Dobson A.,Duong T.,Callanan M.,Lick S.,Hamrick A.,Cano R.,Klaenhammer T.R.
Complete genome sequence of the probiotic lactic acid bacterium Lactobacillus acidophilus NCFM.
Proc. Natl. Acad. Sci. U.S.A.
102
3906-3912
2005
953149
Barrangou R.,Azcarate-Peril M.A.,Duong T.,Conners S.B.,Kelly R.M.,Klaenhammer T.R.
Global analysis of carbohydrate utilization by Lactobacillus acidophilus using cDNA microarrays.
Proc. Natl. Acad. Sci. U.S.A.
103
3816-3821
2006
953150
Fredslund F.,Hachem M.A.,Larsen R.J.,Sorensen P.G.,Coutinho P.M.,Lo Leggio L.,Svensson B.
Crystal structure of alpha-galactosidase from Lactobacillus acidophilus NCFM: insight into tetramer formation and substrate binding.
J. Mol. Biol.
412
466-480
2011
