Sequence of RB11A_HUMAN
EC Number:3.6.5.2
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
GTP + H2O = GDP + phosphate
Other sequences found for EC No. 3.6.5.2
General information:
Sequence
0 MGTRDDEYDY LFKVVLIGDS GVGKSNLLSR FTRNEFNLES KSTIGVEFAT RSIQVDGKTI
60 KAQIWDTAGQ ERYRAITSAY YRGAVGALLV YDIAKHLTYE NVERWLKELR DHADSNIVIM
120 LVGNKSDLRH LRAVPTDEAR AFAEKNGLSF IETSALDSTN VEAAFQTILT EIYRIVSQKQ
180 MSDRRENDMS PSNNVVPIHV PPTTENKPKV QCCQNI
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
83248
Drivas G.T.,Shih A.,Coutavas E.E.,D'Eustachio P.,Rush M.G.
Identification and characterization of a human homolog of the Schizosaccharomyces pombe ras-like gene YPT-3.
Oncogene
6
3-9
1991
83250
Gromov P.S.,Celis J.E.,Hansen C.,Tommerup N.,Gromova I.,Madsen P.
Human rab11a: transcription, chromosome mapping and effect on the expression levels of host GTP-binding proteins.
FEBS Lett.
429
359-364
1998
83254
Ota T.,Suzuki Y.,Nishikawa T.,Otsuki T.,Sugiyama T.,Irie R.,Wakamatsu A.,Hayashi K.,Sato H.,Nagai K.,Kimura K.,Makita H.,Sekine M.,Obayashi M.,Nishi T.,Shibahara T.,Tanaka T.,Ishii S.,Yamamoto J.,Saito K.,Kawai Y.,Isono Y.,Nakamura Y.,Nagahari K.,Murakami K.,Yasuda T.,Iwayanagi T.,Wagatsuma M.,Shiratori A.,Sudo H.,Hosoiri T.,Kaku Y.,Kodaira H.,Kondo H.,Sugawara M.,Takahashi M.,Kanda K.,Yokoi T.,Furuya T.,Kikkawa E.,Omura Y.,Abe K.,Kamihara K.,Katsuta N.,Sato K.,Tanikawa M.,Yamazaki M.,Ninomiya K.,Ishibashi T.,Yamashita H.,Murakawa K.,Fujimori K.,Tanai H.,Kimata M.,Watanabe M.,Hiraoka S.,Chiba Y.,Ishida S.,Ono Y.,Takiguchi S.,Watanabe S.,Yosida M.,Hotuta T.,Kusano J.,Kanehori K.,Takahashi-Fujii A.,Hara H.,Tanase T.-O.,Nomura Y.,Togiya S.,Komai F.,Hara R.,Takeuchi K.,Arita M.,Imose N.,Musashino K.,Yuuki H.,Oshima A.,Sasaki N.,Aotsuka S.,Yoshikawa Y.,Matsunawa H.,Ichihara T.,Shiohata N.,Sano S.,Moriya S.,Momiyama H.,Satoh N.,Takami S.,Terashima Y.,Suzuki O.,Nakagawa S.,Senoh A.,Mizoguchi H.,Goto Y.,Shimizu F.,Wakebe H.,Hishigaki H.,Watanabe T.,Sugiyama A.,Takemoto M.,Kawakami B.,Yamazaki M.,Watanabe K.,Kumagai A.,Itakura S.,Fukuzumi Y.,Fujimori Y.,Komiyama M.,Tashiro H.,Tanigami A.,Fujiwara T.,Ono T.,Yamada K.,Fujii Y.,Ozaki K.,Hirao M.,Ohmori Y.,Kawabata A.,Hikiji T.,Kobatake N.,Inagaki H.,Ikema Y.,Okamoto S.,Okitani R.,Kawakami T.,Noguchi S.,Itoh T.,Shigeta K.,Senba T.,Matsumura K.,Nakajima Y.,Mizuno T.,Morinaga M.,Sasaki M.,Togashi T.,Oyama M.,Hata H.,Watanabe M.,Komatsu T.,Mizushima-Sugano J.,Satoh T.,Shirai Y.,Takahashi Y.,Nakagawa K.,Okumura K.,Nagase T.,Nomura N.,Kikuchi H.,Masuho Y.,Yamashita R.,Nakai K.,Yada T.,Nakamura Y.,Ohara O.,Isogai T.,Sugano S.
Complete sequencing and characterization of 21,243 full-length human cDNAs.
Nat. Genet.
36
40-45
2004
83255
Zody M.C.,Garber M.,Sharpe T.,Young S.K.,Rowen L.,O'Neill K.,Whittaker C.A.,Kamal M.,Chang J.L.,Cuomo C.A.,Dewar K.,FitzGerald M.G.,Kodira C.D.,Madan A.,Qin S.,Yang X.,Abbasi N.,Abouelleil A.,Arachchi H.M.,Baradarani L.,Birditt B.,Bloom S.,Bloom T.,Borowsky M.L.,Burke J.,Butler J.,Cook A.,DeArellano K.,DeCaprio D.,Dorris L. III,Dors M.,Eichler E.E.,Engels R.,Fahey J.,Fleetwood P.,Friedman C.,Gearin G.,Hall J.L.,Hensley G.,Johnson E.,Jones C.,Kamat A.,Kaur A.,Locke D.P.,Madan A.,Munson G.,Jaffe D.B.,Lui A.,Macdonald P.,Mauceli E.,Naylor J.W.,Nesbitt R.,Nicol R.,O'Leary S.B.,Ratcliffe A.,Rounsley S.,She X.,Sneddon K.M.B.,Stewart S.,Sougnez C.,Stone S.M.,Topham K.,Vincent D.,Wang S.,Zimmer A.R.,Birren B.W.,Hood L.,Lander E.S.,Nusbaum C.
Analysis of the DNA sequence and duplication history of human chromosome 15.
Nature
440
671-675
2006
83257
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Genome Res.
14
2121-2127
2004
83259
Hales C.M.,Griner R.,Hobdy-Henderson K.C.,Dorn M.C.,Hardy D.,Kumar R.,Navarre J.,Chan E.K.L.,Lapierre L.A.,Goldenring J.R.
Identification and characterization of a family of Rab11-interacting proteins.
J. Biol. Chem.
276
39067-39075
2001
83260
Wallace D.M.,Lindsay A.J.,Hendrick A.G.,McCaffrey M.W.
Rab11-FIP4 interacts with Rab11 in a GTP-dependent manner and its overexpression condenses the Rab11 positive compartment in HeLa cells.
Biochem. Biophys. Res. Commun.
299
770-779
2002
83261
Lindsay A.J.,Hendrick A.G.,Cantalupo G.,Senic-Matuglia F.,Goud B.,Bucci C.,McCaffrey M.W.
Rab coupling protein (RCP), a novel Rab4 and Rab11 effector protein.
J. Biol. Chem.
277
12190-12199
2002
83262
Lindsay A.J.,McCaffrey M.W.
Rab11-FIP2 functions in transferrin recycling and associates with endosomal membranes via its COOH-terminal domain.
J. Biol. Chem.
277
27193-27199
2002
83263
Lindsay A.J.,McCaffrey M.W.
Characterisation of the Rab binding properties of Rab coupling protein (RCP) by site-directed mutagenesis.
FEBS Lett.
571
86-92
2004
83264
Junutula J.R.,Schonteich E.,Wilson G.M.,Peden A.A.,Scheller R.H.,Prekeris R.
Molecular characterization of Rab11 interactions with members of the family of Rab11-interacting proteins.
J. Biol. Chem.
279
33430-33437
2004
83265
Lindsay A.J.,McCaffrey M.W.
The C2 domains of the class I Rab11 family of interacting proteins target recycling vesicles to the plasma membrane.
J. Cell Sci.
117
4365-4375
2004
83266
Peden A.A.,Schonteich E.,Chun J.,Junutula J.R.,Scheller R.H.,Prekeris R.
The RCP-Rab11 complex regulates endocytic protein sorting.
Mol. Biol. Cell
15
3530-3541
2004
83267
Fielding A.B.,Schonteich E.,Matheson J.,Wilson G.,Yu X.,Hickson G.R.,Srivastava S.,Baldwin S.A.,Prekeris R.,Gould G.W.
Rab11-FIP3 and FIP4 interact with Arf6 and the exocyst to control membrane traffic in cytokinesis.
EMBO J.
24
3389-3399
2005
83268
Wilson G.M.,Fielding A.B.,Simon G.C.,Yu X.,Andrews P.D.,Hames R.S.,Frey A.M.,Peden A.A.,Gould G.W.,Prekeris R.
The FIP3-Rab11 protein complex regulates recycling endosome targeting to the cleavage furrow during late cytokinesis.
Mol. Biol. Cell
16
849-860
2005
83269
Lock J.G.,Stow J.L.
Rab11 in recycling endosomes regulates the sorting and basolateral transport of E-cadherin.
Mol. Biol. Cell
16
1744-1755
2005
83270
Shirane M.,Nakayama K.I.
Protrudin induces neurite formation by directional membrane trafficking.
Science
314
818-821
2006
83271
Swiatecka-Urban A.,Talebian L.,Kanno E.,Moreau-Marquis S.,Coutermarsh B.,Hansen K.,Karlson K.H.,Barnaby R.,Cheney R.E.,Langford G.M.,Fukuda M.,Stanton B.A.
Myosin Vb is required for trafficking of the cystic fibrosis transmembrane conductance regulator in Rab11a-specific apical recycling endosomes in polarized human airway epithelial cells.
J. Biol. Chem.
282
23725-23736
2007
83272
Westlake C.J.,Junutula J.R.,Simon G.C.,Pilli M.,Prekeris R.,Scheller R.H.,Jackson P.K.,Eldridge A.G.
Identification of Rab11 as a small GTPase binding protein for the Evi5 oncogene.
Proc. Natl. Acad. Sci. U.S.A.
104
1236-1241
2007
83273
Pohl C.,Jentsch S.
Final stages of cytokinesis and midbody ring formation are controlled by BRUCE.
Cell
132
832-845
2008
83274
Chu B.-B.,Ge L.,Xie C.,Zhao Y.,Miao H.-H.,Wang J.,Li B.-L.,Song B.-L.
Requirement of myosin Vb.Rab11a.Rab11-FIP2 complex in cholesterol-regulated translocation of NPC1L1 to the cell surface.
J. Biol. Chem.
284
22481-22490
2009
83275
Bryant D.M.,Datta A.,Rodriguez-Fraticelli A.E.,Peraenen J.,Martin-Belmonte F.,Mostov K.E.
A molecular network for de novo generation of the apical surface and lumen.
Nat. Cell Biol.
12
1035-1045
2010
83276
Cullinane A.R.,Straatman-Iwanowska A.,Zaucker A.,Wakabayashi Y.,Bruce C.K.,Luo G.,Rahman F.,Gurakan F.,Utine E.,Ozkan T.B.,Denecke J.,Vukovic J.,Di Rocco M.,Mandel H.,Cangul H.,Matthews R.P.,Thomas S.G.,Rappoport J.Z.,Arias I.M.,Wolburg H.,Knisely A.S.,Kelly D.A.,Muller F.,Maher E.R.,Gissen P.
Mutations in VIPAR cause an arthrogryposis, renal dysfunction and cholestasis syndrome phenotype with defects in epithelial polarization.
Nat. Genet.
42
303-312
2010
83277
Burkard T.R.,Planyavsky M.,Kaupe I.,Breitwieser F.P.,Buerckstuemmer T.,Bennett K.L.,Superti-Furga G.,Colinge J.
Initial characterization of the human central proteome.
BMC Syst. Biol.
5
17-17
2011
83278
Matsuzaki F.,Shirane M.,Matsumoto M.,Nakayama K.I.
Protrudin serves as an adaptor molecule that connects KIF5 and its cargoes in vesicular transport during process formation.
Mol. Biol. Cell
22
4602-4620
2011
83279
Roland J.T.,Bryant D.M.,Datta A.,Itzen A.,Mostov K.E.,Goldenring J.R.
Rab GTPase-Myo5B complexes control membrane recycling and epithelial polarization.
Proc. Natl. Acad. Sci. U.S.A.
108
2789-2794
2011
83280
Seto S.,Tsujimura K.,Koide Y.
Rab GTPases regulating phagosome maturation are differentially recruited to mycobacterial phagosomes.
Traffic
12
407-420
2011
83281
Longatti A.,Lamb C.A.,Razi M.,Yoshimura S.,Barr F.A.,Tooze S.A.
TBC1D14 regulates autophagosome formation via Rab11- and ULK1-positive recycling endosomes.
J. Cell Biol.
197
659-675
2012
83282
Lee Y.,Chung S.,Baek I.K.,Lee T.H.,Paik S.Y.,Lee J.
UNC119a bridges the transmission of Fyn signals to Rab11, leading to the completion of cytokinesis.
Cell Cycle
12
1303-1315
2013
83283
Catherman A.D.,Durbin K.R.,Ahlf D.R.,Early B.P.,Fellers R.T.,Tran J.C.,Thomas P.M.,Kelleher N.L.
Large-scale top down proteomics of the human proteome: membrane proteins, mitochondria, and senescence.
Mol. Cell. Proteomics
12
3465-3473
2013
83284
Sakaguchi A.,Sato M.,Sato K.,Gengyo-Ando K.,Yorimitsu T.,Nakai J.,Hara T.,Sato K.,Sato K.
REI-1 is a guanine nucleotide exchange factor regulating RAB-11 localization and function in C. elegans embryos.
Dev. Cell
35
211-221
2015
83285
Vaca Jacome A.S.,Rabilloud T.,Schaeffer-Reiss C.,Rompais M.,Ayoub D.,Lane L.,Bairoch A.,Van Dorsselaer A.,Carapito C.
N-terminome analysis of the human mitochondrial proteome.
Proteomics
15
2519-2524
2015
83286
Oguchi M.E.,Noguchi K.,Fukuda M.
TBC1D12 is a novel Rab11-binding protein that modulates neurite outgrowth of PC12 cells.
PLoS ONE
12
0-0
2017
83287
Sobajima T.,Yoshimura S.I.,Maeda T.,Miyata H.,Miyoshi E.,Harada A.
The Rab11-binding protein RELCH/KIAA1468 controls intracellular cholesterol distribution.
J. Cell Biol.
217
1777-1796
2018
83288
Gan J.,Scott N.E.,Newson J.P.M.,Wibawa R.R.,Wong Fok Lung T.,Pollock G.L.,Ng G.Z.,van Driel I.,Pearson J.S.,Hartland E.L.,Giogha C.
The Salmonella effector SseK3 targets small Rab GTPases.
Front. Cell. Infect. Microbiol.
10
419-419
2020
83289
Serwas N.K.,Hoeger B.,Ardy R.C.,Stulz S.V.,Sui Z.,Memaran N.,Meeths M.,Krolo A.,Yuece Petronczki O.,Pfajfer L.,Hou T.Z.,Halliday N.,Santos-Valente E.,Kalinichenko A.,Kennedy A.,Mace E.M.,Mukherjee M.,Tesi B.,Schrempf A.,Pickl W.F.,Loizou J.I.,Kain R.,Bidmon-Fliegenschnee B.,Schickel J.N.,Glauzy S.,Huemer J.,Garncarz W.,Salzer E.,Pierides I.,Bilic I.,Thiel J.,Priftakis P.,Banerjee P.P.,Foerster-Waldl E.,Medgyesi D.,Huber W.D.,Orange J.S.,Meffre E.,Sansom D.M.,Bryceson Y.T.,Altman A.,Boztug K.
Human DEF6 deficiency underlies an immunodeficiency syndrome with systemic autoimmunity and aberrant CTLA-4 homeostasis.
Nat. Commun.
10
3106-3106
2019
83290
Serwas N.K.,Hoeger B.,Ardy R.C.,Stulz S.V.,Sui Z.,Memaran N.,Meeths M.,Krolo A.,Petronczki O.Y.,Pfajfer L.,Hou T.Z.,Halliday N.,Santos-Valente E.,Kalinichenko A.,Kennedy A.,Mace E.M.,Mukherjee M.,Tesi B.,Schrempf A.,Pickl W.F.,Loizou J.I.,Kain R.,Bidmon-Fliegenschnee B.,Schickel J.N.,Glauzy S.,Huemer J.,Garncarz W.,Salzer E.,Pierides I.,Bilic I.,Thiel J.,Priftakis P.,Banerjee P.P.,Foerster-Waldl E.,Medgyesi D.,Huber W.D.,Orange J.S.,Meffre E.,Sansom D.M.,Bryceson Y.T.,Altman A.,Boztug K.
Nat. Commun.
10
4555-4555
2019
83291
Eathiraj S.,Pan X.,Ritacco C.,Lambright D.G.
Structural basis of family-wide Rab GTPase recognition by rabenosyn-5.
Nature
436
415-419
2005
83292
Pasqualato S.,Cherfils J.
Crystallographic evidence for substrate-assisted GTP hydrolysis by a small GTP binding protein.
Structure
13
533-540
2005
83293
Eathiraj S.,Mishra A.,Prekeris R.,Lambright D.G.
Structural basis for Rab11-mediated recruitment of FIP3 to recycling endosomes.
J. Mol. Biol.
364
121-135
2006
83294
Shiba T.,Koga H.,Shin H.-W.,Kawasaki M.,Kato R.,Nakayama K.,Wakatsuki S.
Structural basis for Rab11-dependent membrane recruitment of a family of Rab11-interacting protein 3 (FIP3)/Arfophilin-1.
Proc. Natl. Acad. Sci. U.S.A.
103
15416-15421
2006
83295
Jagoe W.N.,Lindsay A.J.,Read R.J.,McCoy A.J.,McCaffrey M.W.,Khan A.R.
Crystal structure of rab11 in complex with rab11 family interacting protein 2.
Structure
14
1273-1283
2006
83296
Jenkins M.L.,Margaria J.P.,Stariha J.T.B.,Hoffmann R.M.,McPhail J.A.,Hamelin D.J.,Boulanger M.J.,Hirsch E.,Burke J.E.
Structural determinants of Rab11 activation by the guanine nucleotide exchange factor SH3BP5.
Nat. Commun.
9
3772-3772
2018
