Any feedback?
Please rate this page
(sequences.php)
(0/150)

BRENDA support

Sequence of HEMA_CVMS

EC Number:3.1.1.53

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
sialate O-acetylesterase
P31614
Murine coronavirus (strain S)
439
49205
Reaction
N-acetyl-O-acetylneuraminate + H2O = N-acetylneuraminate + acetate
Other sequences found for EC No. 3.1.1.53

General information:

Sequence
show sequence in fasta format
  0 MGCMCIAMAP RTLLLLIGCQ LVFGFNEPLN IVSHLNDDWF LFGDSRSDCT YVENNGHPKL
 60 DWLDLDPKLC NSGRISAKSG NSLFRSFHFI DFYNYSGEGD QVIFYEGVNF SPSHGFKCLA
120 YGDNKRWMGN KARFYARVYE KMAQYRSLSF VNVSYAYGGN AKPTSICKDK TLTLNNPTFI
180 SKESNYVDYY YESEANFTLQ GCDEFIVPLC VFNGHSKGSS SDPANKYYTD SQSYYNMDTG
240 VLYGFNSTLD VGNTVQNPGL DLTCRYLALT PGNYKAVSLE YLLSLPSKAI CLRKPKSFMP
300 VQVVDSRWNS TRQSDNMTAV ACQLPYCFFR NTSADYSGGT HDVHHGDFHF RQLLSGLLYN
360 VSCIAQQGAF VYNNVSSSWP AYGYGHCPTA ANIGYMAPVC IYDPLPVILL GVLLGIAVLI
420 IVFLMFYFMT DSGVRLHEA
Download this sequence
in fasta format
Download all sequences for 3.1.1.53
in fasta format
in csv (Excel, OpenOffice) format
Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
937152
Smits S.L.,Gerwig G.J.,van Vliet A.L.,Lissenberg A.,Briza P.,Kamerling J.P.,Vlasak R.,de Groot R.J.
Nidovirus sialate-O-acetylesterases: evolution and substrate specificity of coronaviral and toroviral receptor-destroying enzymes.
J. Biol. Chem.
280
6933-6941
2005
937153
Lissenberg A.,Vrolijk M.M.,van Vliet A.L.,Langereis M.A.,de Groot-Mijnes J.D.,Rottier P.J.,de Groot R.J.
Luxury at a cost? Recombinant mouse hepatitis viruses expressing the accessory hemagglutinin esterase protein display reduced fitness in vitro.
J. Virol.
79
15054-15063
2005
937155
Yokomori K.,Banner L.R.,Lai M.M.C.
Heterogeneity of gene expression of the hemagglutinin-esterase (HE) protein of murine coronaviruses.
Virology
183
647-657
1991
937156
Wurzer W.J.,Obojes K.,Vlasak R.
The sialate-4-O-acetylesterases of coronaviruses related to mouse hepatitis virus: a proposal to reorganize group 2 Coronaviridae.
J. Gen. Virol.
83
395-402
2002
937157
Langereis M.A.,Zeng Q.,Heesters B.A.,Huizinga E.G.,de Groot R.J.
The murine coronavirus hemagglutinin-esterase receptor-binding site: a major shift in ligand specificity through modest changes in architecture.
PLoS Pathog.
8
0-0
2012