Sequence of DESII_STRVZ
EC Number:4.3.1.30
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
dTDP-4-amino-4,6-dideoxy-alpha-D-glucopyranose + S-adenosyl-L-methionine + reduced acceptor = dTDP-3-dehydro-4,6-dideoxy-alpha-D-glucopyranose + NH3 + L-methionine + 5'-deoxyadenosine + acceptor
Other sequences found for EC No. 4.3.1.30
General information:
Sequence
0 MTAPALSATA PAERCAHPGA DLGAAVHAVG QTLAAGGLVP PDEAGTTARH LVRLAVRYGN
60 SPFTPLEEAR HDLGVDRDAF RRLLALFGQV PELRTAVETG PAGAYWKNTL LPLEQRGVFD
120 AALARKPVFP YSVGLYPGPT CMFRCHFCVR VTGARYDPSA LDAGNAMFRS VIDEIPAGNP
180 SAMYFSGGLE PLTNPGLGSL AAHATDHGLR PTVYTNSFAL TERTLERQPG LWGLHAIRTS
240 LYGLNDEEYE QTTGKKAAFR RVRENLRRFQ QLRAERESPI NLGFAYIVLP GRASRLLDLV
300 DFIADLNDAG QGRTIDFVNI REDYSGRDDG KLPQEERAEL QEALNAFEER VRERTPGLHI
360 DYGYALNSLR TGADAELLRI KPATMRPTAH PQVAVQVDLL GDVYLYREAG FPDLDGATRY
420 IAGRVTPDTS LTEVVRDFVE RGGEVAAVDG DEYFMDGFDQ VVTARLNQLE RDAADGWEEA
480 RGFLR
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
918398
Xue Y.,Zhao L.,Liu H.W.,Sherman D.H.
A gene cluster for macrolide antibiotic biosynthesis in Streptomyces venezuelae: architecture of metabolic diversity.
Proc. Natl. Acad. Sci. U.S.A.
95
12111-12116
1998
918399
Szu P.H.,Ruszczycky M.W.,Choi S.H.,Yan F.,Liu H.W.
Characterization and mechanistic studies of DesII: a radical S-adenosyl-L-methionine enzyme involved in the biosynthesis of TDP-D-desosamine.
J. Am. Chem. Soc.
131
14030-14042
2009
918400
Szu P.H.,He X.,Zhao L.,Liu H.W.
Biosynthesis of TDP-D-desosamine: identification of a strategy for C4 deoxygenation.
Angew. Chem. Int. Ed. Engl.
44
6742-6746
2005
918401
Ruszczycky M.W.,Choi S.H.,Liu H.W.
Stoichiometry of the redox neutral deamination and oxidative dehydrogenation reactions catalyzed by the radical SAM enzyme DesII.
J. Am. Chem. Soc.
132
2359-2369
2010
918402
Ruszczycky M.W.,Choi S.H.,Mansoorabadi S.O.,Liu H.W.
Mechanistic studies of the radical S-adenosyl-L-methionine enzyme DesII: EPR characterization of a radical intermediate generated during its catalyzed dehydrogenation of TDP-D-quinovose.
J. Am. Chem. Soc.
133
7292-7295
2011
