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Sequence of COQ5_YEAST

EC Number:2.1.1.201

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
2-methoxy-6-polyprenyl-1,4-benzoquinol methylase
P49017
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
307
34685
Reaction
S-adenosyl-L-methionine + 2-methoxy-6-all-trans-polyprenyl-1,4-benzoquinol = S-adenosyl-L-homocysteine + 6-methoxy-3-methyl-2-all-trans-polyprenyl-1,4-benzoquinol
Other sequences found for EC No. 2.1.1.201

General information:

Sequence
show sequence in fasta format
  0 MLISSRIVRS SLVNVPLRLS RCFTQAHRAC KEEEVNSPLS SAAEQPEQKY THFGSKTVLK
 60 STKQKLVGDV FSSVANRYDL MNDVMSLGIH RLWKDHFINK LDAGKRPNST TPLNFIDVAG
120 GSGDIAFGLL DHAESKFGDT ESTMDIVDIN PDMLKEGEKR AMEQGKYFKD PRVRFLVSNG
180 EKLEEIDSDS KDIYTVSFGI RNFTDIQKGL NTAYRVLKPG GIFYCLEFSK IENPLMDFAY
240 QQWAKVLPVM GSMIANDYDS YQYLVESIER FPDQETFKSM IEKAGFKSAG YESLTFGICA
300 IHWGIKV
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
912623
Bowman S.,Churcher C.M.,Badcock K.,Brown D.,Chillingworth T.,Connor R.,Dedman K.,Devlin K.,Gentles S.,Hamlin N.,Hunt S.,Jagels K.,Lye G.,Moule S.,Odell C.,Pearson D.,Rajandream M.A.,Rice P.,Skelton J.,Walsh S.V.,Whitehead S.,Barrell B.G.
The nucleotide sequence of Saccharomyces cerevisiae chromosome XIII.
Nature
387
90-93
1997
912624
Engel S.R.,Dietrich F.S.,Fisk D.G.,Binkley G.,Balakrishnan R.,Costanzo M.C.,Dwight S.S.,Hitz B.C.,Karra K.,Nash R.S.,Weng S.,Wong E.D.,Lloyd P.,Skrzypek M.S.,Miyasato S.R.,Simison M.,Cherry J.M.
The reference genome sequence of Saccharomyces cerevisiae: Then and now.
G3 (Bethesda)
4
389-398
2014
912625
Hu Y.,Rolfs A.,Bhullar B.,Murthy T.V.S.,Zhu C.,Berger M.F.,Camargo A.A.,Kelley F.,McCarron S.,Jepson D.,Richardson A.,Raphael J.,Moreira D.,Taycher E.,Zuo D.,Mohr S.,Kane M.F.,Williamson J.,Simpson A.J.G.,Bulyk M.L.,Harlow E.,Marsischky G.,Kolodner R.D.,LaBaer J.
Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae.
Genome Res.
17
536-543
2007
912626
Dibrov E.,Robinson K.M.,Lemire B.D.
The COQ5 gene encodes a yeast mitochondrial protein necessary for ubiquinone biosynthesis and the assembly of the respiratory chain.
J. Biol. Chem.
272
9175-9181
1997
912627
Barkovich R.J.,Shtanko A.,Shepherd J.A.,Lee P.T.,Myles D.C.,Tzagoloff A.,Clarke C.F.
Characterization of the COQ5 gene from Saccharomyces cerevisiae. Evidence for a C-methyltransferase in ubiquinone biosynthesis.
J. Biol. Chem.
272
9182-9188
1997
912628
Huh W.-K.,Falvo J.V.,Gerke L.C.,Carroll A.S.,Howson R.W.,Weissman J.S.,O'Shea E.K.
Global analysis of protein localization in budding yeast.
Nature
425
686-691
2003
912629
Ghaemmaghami S.,Huh W.-K.,Bower K.,Howson R.W.,Belle A.,Dephoure N.,O'Shea E.K.,Weissman J.S.
Global analysis of protein expression in yeast.
Nature
425
737-741
2003
912630
Baba S.W.,Belogrudov G.I.,Lee J.C.,Lee P.T.,Strahan J.,Shepherd J.N.,Clarke C.F.
Yeast Coq5 C-methyltransferase is required for stability of other polypeptides involved in coenzyme Q biosynthesis.
J. Biol. Chem.
279
10052-10059
2004
912631
He C.H.,Xie L.X.,Allan C.M.,Tran U.C.,Clarke C.F.
Coenzyme Q supplementation or over-expression of the yeast Coq8 putative kinase stabilizes multi-subunit Coq polypeptide complexes in yeast coq null mutants.
Biochim. Biophys. Acta
1841
630-644
2014
912632
Dai Y.N.,Zhou K.,Cao D.D.,Jiang Y.L.,Meng F.,Chi C.B.,Ren Y.M.,Chen Y.,Zhou C.Z.
Crystal structures and catalytic mechanism of the C-methyltransferase Coq5 provide insights into a key step of the yeast coenzyme Q synthesis pathway.
Acta Crystallogr. D
70
2085-2092
2014