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Sequence of NDHS_PAENI

EC Number:1.5.99.4

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
nicotine 6-hydroxylase
Q59128
Paenarthrobacter nicotinovorans
165
17511
Reaction
(S)-nicotine + acceptor + H2O = (S)-6-hydroxynicotine + reduced acceptor

General information:

Sequence
show sequence in fasta format
  0 MTTPSPSDRV EIDVEVNGRR RTVAVDARET LADHLRNDQK LTGIKLGCEH GVCGACTILM
 60 DGAAVRSCLT LAAQGDGRSI RTVEDLSDGA LSPLQEAFKR HHALQCGFCT AGFLMSATEL
120 LEANPSPTKE EVIEALSGNL CRCTGYQTIV EAVLDAPGQI GNKNG
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
868901
Grether-Beck S.,Igloi G.L.,Pust S.,Schiltz E.,Decker K.,Brandsch R.
Structural analysis and molybdenum-dependent expression of the pAO1-encoded nicotine dehydrogenase genes of Arthrobacter nicotinovorans.
Mol. Microbiol.
13
929-936
1994
868902
Baitsch D.,Sandu C.,Brandsch R.,Igloi G.L.
Gene cluster on pAO1 of Arthrobacter nicotinovorans involved in degradation of the plant alkaloid nicotine: cloning, purification, and characterization of 2,6-dihydroxypyridine 3-hydroxylase.
J. Bacteriol.
183
5262-5267
2001
868903
Igloi G.L.,Brandsch R.
Sequence of the 165-kilobase catabolic plasmid pAO1 from Arthrobacter nicotinovorans and identification of a pAO1-dependent nicotine uptake system.
J. Bacteriol.
185
1976-1986
2003
868904
Decker K.,Bleeg H.
Induction and purification of stereospecific nicotine oxidizing enzymes from Arthrobacter oxidans.
Biochim. Biophys. Acta
105
313-324
1965
868905
Gurusamy R.,Natarajan S.
Current status on biochemistry and molecular biology of microbial degradation of nicotine.
ScientificWorldJournal
2013
125385-125385
2013