Sequence of PTPS_RAT
EC Number:4.2.3.12
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
7,8-dihydroneopterin 3'-triphosphate = 6-pyruvoyl-5,6,7,8-tetrahydropterin + triphosphate
Other sequences found for EC No. 4.2.3.12
General information:
Sequence
0 MNAAVGLRRR ARLSRLVSFS ASHRLHSPSL SAEENLKVFG KCNNPNGHGH NYKVVVTIHG
60 EIDPVTGMVM NLTDLKEYME EAIMKPLDHK NLDLDVPYFA DVVSTTENVA VYIWENLQRL
120 LPVGALYKVK VYETDNNIVV YKGE
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
80594
Inoue Y.,Kawasaki Y.,Harada T.,Hatakeyama K.,Kagamiyama H.
Purification and cDNA cloning of rat 6-pyruvoyl-tetrahydropterin synthase.
J. Biol. Chem.
266
20791-20796
1991
80595
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Genome Res.
14
2121-2127
2004
80596
Nar H.,Huber R.,Heizmann C.W.,Thoeny B.,Buergisser D.
Three-dimensional structure of 6-pyruvoyl tetrahydropterin synthase, an enzyme involved in tetrahydrobiopterin biosynthesis.
EMBO J.
13
1255-1262
1994
80597
Ploom T.,Thoeny B.,Yim J.,Lee S.,Nar H.,Leimbacher W.,Richardson J.,Huber R.,Auerbach G.
Crystallographic and kinetic investigations on the mechanism of 6-pyruvoyl tetrahydropterin synthase.
J. Mol. Biol.
286
851-860
1999
