Sequence of FADS2_RAT

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
acyl-CoA 6-desaturase
Q9Z122
Rattus norvegicus
444
52380
Reaction
alpha-linolenoyl-CoA + 2 ferrocytochrome b5 + O2 + 2 H+ = stearidonoyl-CoA + 2 ferricytochrome b5 + 2 H2O
Sequences with same EC No.
Sequence
show sequence in fasta format
  0 MGKGGNQGEG STELQAPMPT FRWEEIQKHN LRTDRWLVID RKVYNVTKWS QRHPGGHRVI
 60 GHYSGEDATD AFRAFHLDLD FVGKFLKPLL IGELAPEEPS LDRGKSSQIT EDFRALKKTA
120 EDMNLFKTNH LFFFLLLSHI IVMESIAWFI LSYFGNGWIP TVITAFVLAT SQAQAGWLQH
180 DYGHLSVYKK SIWNHIVHKF VIGHLKGASA NWWNHRHFQH HAKPNIFHKD PDIKSLHVFV
240 LGEWQPLEYG KKKLKYLPYN HQHEYFFLIG PPLLIPMYFQ YQIIMTMIRR RDWVDLAWAI
300 SYYARFFYTY IPFYGILGAL VFLNFIRFLE SHWFVWVTQM NHIVMEIDLD HYRDWFSSQL
360 AATCNVEQSF FNDWFSGHLN FQIEHHLFPT MPRHNLHKIA PLVKSLCAKH GIEYQEKPLL
420 RALLDIVSSL KKSGELWLDA YLHK
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
892184
Aki T.,Shimada Y.,Inagaki K.,Higashimoto H.,Kawamoto S.,Shigeta S.,Ono K.,Suzuki O.
Molecular cloning and functional characterization of rat Delta-6 fatty acid desaturase.
Biochem. Biophys. Res. Commun.
255
575-579
1999
892185
Gregory M.K.,Gibson R.A.,Cook-Johnson R.J.,Cleland L.G.,James M.J.
Elongase reactions as control points in long-chain polyunsaturated fatty acid synthesis.
PLoS ONE
6
0-0
2011
892186
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Genome Res.
14
2121-2127
2004
892187
Brenner R.R.
The desaturation step in the animal biosynthesis of polyunsaturated fatty acids.
Lipids
6
567-575
1971
892188
Brenner R.R.
Hormonal modulation of delta-6 and delta-5 desaturases: case of diabetes.
Prostaglandins Leukot. Essent. Fatty Acids
68
151-162
2003
892189
D'andrea S.,Guillou H.,Jan S.,Catheline D.,Thibault J.N.,Bouriel M.,Rioux V.,Legrand P.
The same rat Delta6-desaturase not only acts on 18- but also on 24-carbon fatty acids in very-long-chain polyunsaturated fatty acid biosynthesis.
Biochem. J.
364
49-55
2002
892190
Guillou H.,D'Andrea S.,Rioux V.,Barnouin R.,Dalaine S.,Pedrono F.,Jan S.,Legrand P.
Distinct roles of endoplasmic reticulum cytochrome b5 and fused cytochrome b5-like domain for rat delta-6-desaturase activity.
J. Lipid Res.
45
32-40
2004
892191
Rioux V.,Pedrono F.,Blanchard H.,Duby C.,Boulier-Monthean N.,Bernard L.,Beauchamp E.,Catheline D.,Legrand P.
Trans-vaccenate is Delta13-desaturated by FADS3 in rodents.
J. Lipid Res.
54
3438-3452
2013