Sequence of ALGG_PSEAE
EC Number:5.1.3.37
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
mannuronan 5-epimerase
Q51371
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
543
59802
Reaction
[mannuronan]-beta-D-mannuronate = [alginate]-alpha-L-guluronate
General information:
Sequence
show sequence in normal format
>Q51371|mannuronan 5-epimerase|EC 5.1.3.37|Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)|Swiss-Prot
MPDISLSIPRRRLPRLRPLAAAVLGAVLLHGQAWAAQPVEKPQPVPAQAGNEPGLTQGLK
ETGNYTVTTAPAEPLHLDPPKLPDLSGYTAAAVEAKIVRKPGGRASVQRMVQQQPLKEFT
GGSNRLAEWVKRQRQMPQAIFIEGGYVNLAQLAGKLPASALEQVEPGVFVARLPIVVSQG
ATLDIDKQVKELRLSQERGAFLVNDGMLFVRDSKVTGWSESKKEPAWFKTPNEFRPFLIS
WGGAEVYLSNSTFTSFGYNASKAYGISISQYSPGMDKQMKRPRPKGWVIDSTIVDSWYGF
YCYEADDLVVKGNTYRDNIVYGIDPHDRSHRLIIADNTVHGTRKKHGIIVSREVNDSFIF
NNRSYENKLSGIVLDRNSEGNLVAYNEVYRNHSDGITLYESGDNLLWGNQVLANRRHGIR
VRNSVNIRLYENLAAGNQLIGVYGHIKDLTNTDRNIALDPFDTKVSLIVVGGKLAGNGSG
PLSVDSPLSLELYRVAMLAPTKSSGISLPGVLGEKQDQILDLLVRQDKAVLIDPVESQAE
LQD
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
854177
Franklin M.J.,Chitnis C.E.,Gacesa P.,Sonesson A.,White D.C.,Ohman D.E.
Pseudomonas aeruginosa AlgG is a polymer level alginate C5-mannuronan epimerase.
J. Bacteriol.
176
1821-1830
1994
854178
Monday S.R.,Schiller N.L.
Alginate synthesis in Pseudomonas aeruginosa: the role of AlgL (alginate lyase) and AlgX.
J. Bacteriol.
178
625-632
1996
854179
Stover C.K.,Pham X.-Q.T.,Erwin A.L.,Mizoguchi S.D.,Warrener P.,Hickey M.J.,Brinkman F.S.L.,Hufnagle W.O.,Kowalik D.J.,Lagrou M.,Garber R.L.,Goltry L.,Tolentino E.,Westbrock-Wadman S.,Yuan Y.,Brody L.L.,Coulter S.N.,Folger K.R.,Kas A.,Larbig K.,Lim R.M.,Smith K.A.,Spencer D.H.,Wong G.K.-S.,Wu Z.,Paulsen I.T.,Reizer J.,Saier M.H. Jr.,Hancock R.E.W.,Lory S.,Olson M.V.
Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen.
Nature
406
959-964
2000
854180
Jain S.,Franklin M.J.,Ertesvaag H.,Valla S.,Ohman D.E.
The dual roles of AlgG in C-5-epimerization and secretion of alginate polymers in Pseudomonas aeruginosa.
Mol. Microbiol.
47
1123-1133
2003
854181
Douthit S.A.,Dlakic M.,Ohman D.E.,Franklin M.J.
Epimerase active domain of Pseudomonas aeruginosa AlgG, a protein that contains a right-handed beta-helix.
J. Bacteriol.
187
4573-4583
2005
854182
Jerga A.,Stanley M.D.,Tipton P.A.
Chemical mechanism and specificity of the C5-mannuronan epimerase reaction.
Biochemistry
45
9138-9144
2006
