Sequence of ALG8_PSEAE
EC Number:2.4.1.33
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
mannuronan synthase
Q52463
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
494
56456
Reaction
GDP-alpha-D-mannuronate + [(1->4)-beta-D-mannuronosyl]n = GDP + [(1->4)-beta-D-mannuronosyl]n+1
General information:
Sequence
0 MMETYKRGLA EATGWLVFLS LLMVLALAVP KTVFDADSKD FILLIGAVGI WRYSMGGVHF
60 LRGMLFLHVV YPYYRRRVRQ LGSAADPSHV FLMVTSFRID ALTTAMVYRS VIREAIDSGY
120 PTTVVCSIVE MSDEVLVRSL WEKMNPPDRV SLDFVRIPGT GKRDGLAYGF RAISRHLPDD
180 DAVVAVIDGD TVLDHGVVKK TVPWFKLFPN VGGLTTNEFC EVQGGYVMSE WHKLRFAQRH
240 INMCSMALSK RVLTMTGRMS VFRARVVTNP EFITDVENDH LEHWRLGRFK FLTGDDKSSW
300 FSLMRLGYDT FYVPDAAINT VEHPPEKSFI KASRKLMYRW YGNNLRQNSR ALKLGARRLG
360 WFTMLVLFDQ RVSMWTSLLG LVVAILASLK YSIAFLLVYL LWIGLTRLVL TLLLSLSGHR
420 IGPAYPLILY YNQIVGALVK IYVFFRLDRQ SWTRQPTKLE RGLASFQRWF NAWSSRAMTF
480 SAASIFVAVL LTIV
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
854787
Maharaj R.,May T.B.,Wang S.-K.,Chakrabarty A.M.
Sequence of the alg8 and alg44 genes involved in the synthesis of alginate by Pseudomonas aeruginosa.
Gene
136
267-269
1993
854788
Stover C.K.,Pham X.-Q.T.,Erwin A.L.,Mizoguchi S.D.,Warrener P.,Hickey M.J.,Brinkman F.S.L.,Hufnagle W.O.,Kowalik D.J.,Lagrou M.,Garber R.L.,Goltry L.,Tolentino E.,Westbrock-Wadman S.,Yuan Y.,Brody L.L.,Coulter S.N.,Folger K.R.,Kas A.,Larbig K.,Lim R.M.,Smith K.A.,Spencer D.H.,Wong G.K.-S.,Wu Z.,Paulsen I.T.,Reizer J.,Saier M.H. Jr.,Hancock R.E.W.,Lory S.,Olson M.V.
Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen.
Nature
406
959-964
2000
854789
Remminghorst U.,Rehm B.H.
In vitro alginate polymerization and the functional role of Alg8 in alginate production by Pseudomonas aeruginosa.
Appl. Environ. Microbiol.
72
298-305
2006
854790
Oglesby L.L.,Jain S.,Ohman D.E.
Membrane topology and roles of Pseudomonas aeruginosa Alg8 and Alg44 in alginate polymerization.
Microbiology
154
1605-1615
2008
