Sequence of AVRB_STRVR

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
23S rRNA (uridine2479-2'-O)-methyltransferase
Q9F5K6
Streptomyces viridochromogenes
287
31215
Reaction
S-adenosyl-L-methionine + uridine2479 in 23S rRNA = S-adenosyl-L-homocysteine + 2'-O-methyluridine2479 in 23S rRNA
Sequences with same EC No.
Sequence
show sequence in fasta format
  0 MARSRGERTP AARRITSRNA RFQQWQALLG NRNKRTRAGE FLVMGVRPIS LAVEHGWPVR
 60 TLLYDGQREL SKWARELLRT VRTEQIAMAP DLLMELGEKN EAPPEVVAVV EMPADDLDRI
120 PVREDFLGVL FDRPTSPGNI GSIIRSADAL GAHGLIVAGH AADVYDPKSV RSSTGSLFSL
180 PAVRVPSPGE VMDWVEARRA AGTPIVLVGT DEHGDCDVFD FDFTQPTLLL IGNETAGLSN
240 AWRTLCDYTV SIPMAGSASS LNAANAATAI LYEAVRQRIS GRTATTP
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
865029
Weitnauer G.,Gaisser S.,Trefzer A.,Stockert S.,Westrich L.,Quiros L.M.,Mendez C.,Salas J.A.,Bechthold A.
An ATP-binding cassette transporter and two rRNA methyltransferases are involved in resistance to avilamycin in the producer organism Streptomyces viridochromogenes Tu57.
Antimicrob. Agents Chemother.
45
690-695
2001
865030
Treede I.,Jakobsen L.,Kirpekar F.,Vester B.,Weitnauer G.,Bechthold A.,Douthwaite S.
The avilamycin resistance determinants AviRa and AviRb methylate 23S rRNA at the guanosine 2535 base and the uridine 2479 ribose.
Mol. Microbiol.
49
309-318
2003
865031
Mosbacher T.G.,Bechthold A.,Schulz G.E.
Structure and function of the antibiotic resistance-mediating methyltransferase AviRb from Streptomyces viridochromogenes.
J. Mol. Biol.
345
535-545
2005