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Sequence of PH3H_STRC4

EC Number:1.14.16.7

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
phenylalanine 3-monooxygenase
F5BFC8
Streptomyces coeruleorubidus
279
31038
Reaction
L-phenylalanine + a 5,6,7,8-tetrahydropteridine + O2 = 3-hydroxy-L-phenylalanine + a 4a-hydroxy-5,6,7,8-tetrahydropteridine
Other sequences found for EC No. 1.14.16.7

General information:

Sequence
show sequence in fasta format
  0 MQGPHAQMTD AAYEIRRSEI AALSTDLAPE DPIPVVEYTE WEHEVWRTVC VDLTARHRTD
 60 AAAEYLESAE QLAVPLDHVP QLRDVSGRLG SISGFTFQSA PALVPLREFC GGLANSVFHS
120 TQYLRHPRSP FYTEDPDLLH DLVGHGNVLA SDRFARLYRL AGNAAARVHS TEALQFIGKV
180 FWFTLECGVV RERGERKAYG ATLVSSYGEL DHFRSADFRP LDIKSLADVE YDISTYQPIL
240 FEADSMDEVE DTVGSFWDTC DDDSIAALLG GTSRSVTPH
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
839875
Rackham E.J.,Gruschow S.,Ragab A.E.,Dickens S.,Goss R.J.
Pacidamycin biosynthesis: identification and heterologous expression of the first uridyl peptide antibiotic gene cluster.
ChemBioChem
11
1700-1709
2010
839877
Zhang W.,Ntai I.,Bolla M.L.,Malcolmson S.J.,Kahne D.,Kelleher N.L.,Walsh C.T.
Nine enzymes are required for assembly of the pacidamycin group of peptidyl nucleoside antibiotics.
J. Am. Chem. Soc.
133
5240-5243
2011
839878
Zhang W.,Ames B.D.,Walsh C.T.
Identification of phenylalanine 3-hydroxylase for meta-tyrosine biosynthesis.
Biochemistry
50
5401-5403
2011