Sequence of NEON_STRFR
EC Number:2.6.1.95
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
neomycin C + 2-oxoglutarate = 6'''-deamino-6'''-oxoneomycin C + L-glutamate
Other sequences found for EC No. 2.6.1.95
General information:
Sequence
0 MTKNSSLLAE FPTCPRDEKD RPRVFTAASG AWLTDESGFR WIDFDNARGS ILLGHGDPVV
60 AEAVARAATG ADGTATGWSR RVDAVLERLH ALCGGEVVGL FRSGTAAVRA AVLAVREATG
120 RPLLLSAGYH GYDPMWYPSE APLEPNADGV VDFFFDLGLL RELLRAPERV AAVVVSPDHM
180 HLSPGWYREL RRLCSAAGVV LVADEVKVGL RYAPGLSTAE LLAPDVWVVA KGMANGHAVS
240 AVGGSRRLLK PLKEVSFTSF FEPTILAAAD AALARVATGE PQRAVREAGD RFLRHARKAL
300 DDASLPVEIA GDGTFFQFVP ATEELEEALY GAANAEGLLF YAGDNQGVSA AFDEAVLGEA
360 ERRFARVCER LAPYAGGEPV GDAARYRVAW NVMDGLRQAP RDREETTGLL ARLLDD
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
831129
Kudo F.,Yamamoto Y.,Yokoyama K.,Eguchi T.,Kakinuma K.
Biosynthesis of 2-deoxystreptamine by three crucial enzymes in Streptomyces fradiae NBRC 12773.
J. Antibiot.
58
766-774
2005
831130
Huang F.,Haydock S.F.,Mironenko T.,Spiteller D.,Li Y.,Spencer J.B.
The neomycin biosynthetic gene cluster of Streptomyces fradiae NCIMB 8233: characterisation of an aminotransferase involved in the formation of 2-deoxystreptamine.
Org. Biomol. Chem.
3
1410-1418
2005
831132
Huang F.,Spiteller D.,Koorbanally N.A.,Li Y.,Llewellyn N.M.,Spencer J.B.
Elaboration of neosamine rings in the biosynthesis of neomycin and butirosin.
ChemBioChem
8
283-288
2007
831133
Clausnitzer D.,Piepersberg W.,Wehmeier U.F.
The oxidoreductases LivQ and NeoQ are responsible for the different 6'-modifications in the aminoglycosides lividomycin and neomycin.
J. Appl. Microbiol.
111
642-651
2011
