Sequence of MOKB_MONPI
EC Number:2.3.1.244
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
2 malonyl-CoA + [2-methylbutanoate polyketide synthase] + 2 NADPH + 3 H+ + S-adenosyl-L-methionine = (S)-2-methylbutanoyl-[2-methylbutanoate polyketide synthase] + 2 CoA + 2 CO2 + 2 NADP+ + S-adenosyl-L-homocysteine + H2O
Other sequences found for EC No. 2.3.1.244
General information:
Sequence
0 MKATAASGTP TPIAVVGMGC RFAGGATDPQ ALWKLLEQGG STWSKTPSSR FNVSGVYHPN
60 GQRVGSMHVR GGHFLDQDPA LFDASFFNMT SEVASCMDPQ QRLILEVVYE ALEAAGIPLE
120 SVAGSNTAVF SGAMYHDYQD SLHRNPETLP RYFITGNAGT MMSSRVSHFY DLRGPSVTVD
180 TACSTTLTAL HLAIQSIRAG EADMAIVAGS NLLLNSDVFV TMSNLGFLSP DGISYSFDPR
240 ANGYGRGEGV AAIILKALPR ALRDGDPIRL VVRETALNQD GRTPAITGPS PEAQACLIRE
300 CYQKAGLDPR QTSYVEAHGT GTPTGDPLEL AAISAAFQGQ PLQIGSVKAN LGHTEAASGL
360 ASVMKVALAL EKGIVPPSAR FLQPSKKLLE ERKFQIPLSS QLWLPIDGIC RASINNFGFG
420 GANAHAIVER YDPAARISTS KPNGHIRPHD SHVEADRGKI YVLSAKDEHS CQEMISRLRD
480 YLNRANPTDE RQFLANMAYT LASRRSNLRW KAACRAHSLA SLLSVLVSDG TRPRRSAEKA
540 RLGWVFTGQG AQWFAMGREL IEAYPVFKEA LIECDGYIKG MGANWSIIDE LRRGEAESRV
600 NEAEFSLPLS TAIQVALVRL LWSWGIRPAA ITSHSSGEVA AAYAVGAFSA RSAIGISYIR
660 GALIAKTQPA PTTKGGMLAV GLSRSEVGEY ITRVQQQGEE YLVVGCINSP SNVTVSGDLS
720 AVVRLEELLH ADQIFARRLK VTQAFHSHHM QPLSGEFREA LVEVFNADIT DTTNACQDVV
780 YASPKTGKRL DDCNHLRDPM HWVESMLFPV EFESSFREMC FDRKDQAQEV DKIIEIGPHG
840 VLSGAIKQIL QLPELAAFDI SYLSCLSRGK SAVDTIQLLA MDLLQGGYPV DLNAVNFPYG
900 CEAAEVQVLS DLPTYPWNHK TRYWKEPRIS RAARQRKIPV HDLIGVQEPL CPPLLHLWQN
960 VLRISDVPWI RDHVVGSRIL FPGAGFISMV IDGLSQICNH DPETCGLSYI LRDVDLAQAL
1020 ILPTDGDEGV DLRLTIRAAD QKSLGMRDWQ RFSVYSIAGD KDDWTEHCTG LIRAQVDHPV
1080 SSSSIQQKTN PPQWSRKMAP QDLWASLHAT GICHGPLFQN IERIESDGQA SWCTLTVADT
1140 VATMPHAYES QHIVHPTTLD SAIQAAYTVL PFMGTLMKTA MVPSRIGGMK IPASFASLEP
1200 GDMLCAQAKI KNQGLSAFTT DVAVFNESDM DEEAGIELEG LTFQSLGAVI SDSRRDLTEN
1260 ESTYSSWHWA PDITLTNSTW LERILSTGTQ SQEIGVMLEL RRCTVHFIQE AIENLTTEDV
1320 ERLSGHLVKF YCWMQAQLAC ATNGELGQDS ADWLRDSEQE RQSLRSRVVA ATNNGEMICR
1380 LGPKLSAILR GELDPLELMM DGQLLSRYYI RAIKWSRSNT QASELVRLCC HKNPRARILE
1440 IGGGTGGCTQ LIVNALGPTK PVGRYDFTDV SAGFFEAARK RFSGWQDVMD FRKLDIEGDP
1500 EVQGFDCGSY DVVLACQVLH ATSNMQRTLN NVRKLLKPGG KLILVETTRD QLDLFFTFGL
1560 LPGWWLSEEP ERQLTPSLSP ELWRSVLSAT GFSGVDLEVR DCDSDEFYMI STMMSTATPG
1620 TPATTLNGPA EVLLVHAGSP PPMDWLQNLQ VALGGKNSSI TSLKALQGVS DLKGKMCVFL
1680 GEMDRTLLES VVSDDFTSLT SMLQYSQGTL WVTRGAAMAS DDPRKALHLG LLRTLRNENH
1740 GRRFVSLDLD PLRDPWTAQS CDAIVNVLNA VGASHEKEFE YAERDGTIHV PRTFSDSSSS
1800 EKEDLVVLEP FQNETRLVRL DVQTPGLLDS LHFKLCSADE AWSSELPEDW VEIEPRAFGL
1860 NFRDIMVAMG QLESNRVMGF ECAGVVTRLS KAATTGAGGL AIGDRVCALM KGHWASRVRT
1920 ARTNVICIPG TLSFEQAASI PLAFTTAYTS LYTVARLQRG EKVLIHGGAG GVGQAAIILA
1980 QLVGAEVFTT AGTHSKRNFL IDKFKLAPDH VFSSRDSGFI EGIRACTNGK GVDVVLNSLA
2040 GPLLQYSFDC LVNFGRFVEI GKKDLEQNSR LNMATFARNV SFSSIDILYW EEAKSAEIFR
2100 ALTEIMRLLE QKTIDLIGPI SEYPMSAIEK AFRTMQSGQH VGKLVVATAE TDMIPVRRGT
2160 MPVALKLDAS YLIVGGLGGI GRRICEWMVD HGARHLLILS RSGRTDPFVT GLQKRGCVVR
2220 IHSCDVADES QLHAVLQQCH EDNMPPIRGI IQAAMVLKDA LVSQMTADDF HVALRPKVQG
2280 SWNLHKIASE VDFFIMLSSL VGVMGGAGQA NYAAAGAFQD ALAQHRVAQG KPAVTIDLGM
2340 VKSIGYVAET DPAVAERLAR IGYQPMHEEE VLAVLERAMS PSSSSAPPSS NPTIPASPAV
2400 IVTGINTGPG PHFTNADWMQ EARFAGIKYR DPLKDDRGGA LSSSQPADED SVRARLSRAS
2460 TEEEATALVV QVMGHRLVTM FGLTESEMSA TQTLSSVGVD SLVAIELRNW ITAQLNVDIS
2520 VFELMEGRTI AEVAEVVVKK YGVGSKV
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
826015
Chen Y.P.,Tseng C.P.,Liaw L.L.,Wang C.L.,Chen I.C.,Wu W.J.,Wu M.D.,Yuan G.F.
Cloning and characterization of monacolin K biosynthetic gene cluster from Monascus pilosus.
J. Agric. Food Chem.
56
5639-5646
2008
826016
Sakai K.,Kinoshita H.,Nihira T.
Identification of mokB involved in monacolin K biosynthesis in Monascus pilosus.
Biotechnol. Lett.
31
1911-1916
2009
826017
Chen Y.-P.,Yuan G.-F.,Hsieh S.-Y.,Lin Y.-S.,Wang W.-Y.,Liaw L.-L.,Tseng C.-P.
Identification of the mokH gene encoding transcription factor for the upregulation of monacolin K biosynthesis in Monascus pilosus.
J. Agric. Food Chem.
58
287-293
2010
826018
Hong S.Y.,Oh J.H.,Lee I.
Simultaneous enrichment of deglycosylated ginsenosides and monacolin K in red ginseng by fermentation with Monascus pilosus.
Biosci. Biotechnol. Biochem.
75
1490-1495
2011
