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Sequence of PHLD_MYCTU

EC Number:3.1.4.3

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
phospholipase C
P9WIA9
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
280
29970
Reaction
a phosphatidylcholine + H2O = 1,2-diacyl-sn-glycerol + phosphocholine
Other sequences found for EC No. 3.1.4.3

General information:

Sequence
  0 DAGVSWKVYR NKTLGPISSV LTYGSLVTSF KQSADPRSDL VRFGVAPSYP ASFAADVLAN
 60 RLPRVSWVIP NVLESEHPAV PAAAGAFAIV NILRILLANP AVWEKTALIV SYDENGGFFD
120 HVVPATAPAG TPGEYVTVPD IDQVPGSGGI RGPIGLGFRV PCFVISPYSR GPQMVHDTFD
180 HTSQLRLLET RFGVPVPNLT AWRRSVTGDM TSTFNFAVPP NSSWPNLDYP GLHALSTVPQ
240 CVPNAALGTI NRGIPYRVPD PQIMPTQETT PTRGIPSGPC
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
74570
Cole S.T.,Brosch R.,Parkhill J.,Garnier T.,Churcher C.M.,Harris D.E.,Gordon S.V.,Eiglmeier K.,Gas S.,Barry C.E. III,Tekaia F.,Badcock K.,Basham D.,Brown D.,Chillingworth T.,Connor R.,Davies R.M.,Devlin K.,Feltwell T.,Gentles S.,Hamlin N.,Holroyd S.,Hornsby T.,Jagels K.,Krogh A.,McLean J.,Moule S.,Murphy L.D.,Oliver S.,Osborne J.,Quail M.A.,Rajandream M.A.,Rogers J.,Rutter S.,Seeger K.,Skelton S.,Squares S.,Squares R.,Sulston J.E.,Taylor K.,Whitehead S.,Barrell B.G.
Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.
Nature
393
537-544
1998
74571
Raynaud C.,Guilhot C.,Rauzier J.,Bordat Y.,Pelicic V.,Manganelli R.,Smith I.,Gicquel B.,Jackson M.
Phospholipases C are involved in the virulence of Mycobacterium tuberculosis.
Mol. Microbiol.
45
203-217
2002
74572
Bakala N'goma J.C.,Schue M.,Carriere F.,Geerlof A.,Canaan S.
Evidence for the cytotoxic effects of Mycobacterium tuberculosis phospholipase C towards macrophages.
Biochim. Biophys. Acta
1801
1305-1313
2010