Sequence of GBA2_MOUSE

glucosylceramidase

Q69ZF3

918

103294

802017

Okazaki N.,Kikuno R.,Ohara R.,Inamoto S.,Koseki H.,Hiraoka S.,Saga Y.,Seino S.,Nishimura M.,Kaisho T.,Hoshino K.,Kitamura H.,Nagase T.,Ohara O.,Koga H.

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

DNA Res.

11

205-218

2004

802018

Carninci P.,Kasukawa T.,Katayama S.,Gough J.,Frith M.C.,Maeda N.,Oyama R.,Ravasi T.,Lenhard B.,Wells C.,Kodzius R.,Shimokawa K.,Bajic V.B.,Brenner S.E.,Batalov S.,Forrest A.R.,Zavolan M.,Davis M.J.,Wilming L.G.,Aidinis V.,Allen J.E.,Ambesi-Impiombato A.,Apweiler R.,Aturaliya R.N.,Bailey T.L.,Bansal M.,Baxter L.,Beisel K.W.,Bersano T.,Bono H.,Chalk A.M.,Chiu K.P.,Choudhary V.,Christoffels A.,Clutterbuck D.R.,Crowe M.L.,Dalla E.,Dalrymple B.P.,de Bono B.,Della Gatta G.,di Bernardo D.,Down T.,Engstrom P.,Fagiolini M.,Faulkner G.,Fletcher C.F.,Fukushima T.,Furuno M.,Futaki S.,Gariboldi M.,Georgii-Hemming P.,Gingeras T.R.,Gojobori T.,Green R.E.,Gustincich S.,Harbers M.,Hayashi Y.,Hensch T.K.,Hirokawa N.,Hill D.,Huminiecki L.,Iacono M.,Ikeo K.,Iwama A.,Ishikawa T.,Jakt M.,Kanapin A.,Katoh M.,Kawasawa Y.,Kelso J.,Kitamura H.,Kitano H.,Kollias G.,Krishnan S.P.,Kruger A.,Kummerfeld S.K.,Kurochkin I.V.,Lareau L.F.,Lazarevic D.,Lipovich L.,Liu J.,Liuni S.,McWilliam S.,Madan Babu M.,Madera M.,Marchionni L.,Matsuda H.,Matsuzawa S.,Miki H.,Mignone F.,Miyake S.,Morris K.,Mottagui-Tabar S.,Mulder N.,Nakano N.,Nakauchi H.,Ng P.,Nilsson R.,Nishiguchi S.,Nishikawa S.,Nori F.,Ohara O.,Okazaki Y.,Orlando V.,Pang K.C.,Pavan W.J.,Pavesi G.,Pesole G.,Petrovsky N.,Piazza S.,Reed J.,Reid J.F.,Ring B.Z.,Ringwald M.,Rost B.,Ruan Y.,Salzberg S.L.,Sandelin A.,Schneider C.,Schoenbach C.,Sekiguchi K.,Semple C.A.,Seno S.,Sessa L.,Sheng Y.,Shibata Y.,Shimada H.,Shimada K.,Silva D.,Sinclair B.,Sperling S.,Stupka E.,Sugiura K.,Sultana R.,Takenaka Y.,Taki K.,Tammoja K.,Tan S.L.,Tang S.,Taylor M.S.,Tegner J.,Teichmann S.A.,Ueda H.R.,van Nimwegen E.,Verardo R.,Wei C.L.,Yagi K.,Yamanishi H.,Zabarovsky E.,Zhu S.,Zimmer A.,Hide W.,Bult C.,Grimmond S.M.,Teasdale R.D.,Liu E.T.,Brusic V.,Quackenbush J.,Wahlestedt C.,Mattick J.S.,Hume D.A.,Kai C.,Sasaki D.,Tomaru Y.,Fukuda S.,Kanamori-Katayama M.,Suzuki M.,Aoki J.,Arakawa T.,Iida J.,Imamura K.,Itoh M.,Kato T.,Kawaji H.,Kawagashira N.,Kawashima T.,Kojima M.,Kondo S.,Konno H.,Nakano K.,Ninomiya N.,Nishio T.,Okada M.,Plessy C.,Shibata K.,Shiraki T.,Suzuki S.,Tagami M.,Waki K.,Watahiki A.,Okamura-Oho Y.,Suzuki H.,Kawai J.,Hayashizaki Y.

The transcriptional landscape of the mammalian genome.

Science

309

1559-1563

2005

802019

Church D.M.,Goodstadt L.,Hillier L.W.,Zody M.C.,Goldstein S.,She X.,Bult C.J.,Agarwala R.,Cherry J.L.,DiCuccio M.,Hlavina W.,Kapustin Y.,Meric P.,Maglott D.,Birtle Z.,Marques A.C.,Graves T.,Zhou S.,Teague B.,Potamousis K.,Churas C.,Place M.,Herschleb J.,Runnheim R.,Forrest D.,Amos-Landgraf J.,Schwartz D.C.,Cheng Z.,Lindblad-Toh K.,Eichler E.E.,Ponting C.P.

Lineage-specific biology revealed by a finished genome assembly of the mouse.

PLoS Biol.

7

0-0

2009

802020

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

Genome Res.

14

2121-2127

2004

802021

Yildiz Y.,Matern H.,Thompson B.,Allegood J.C.,Warren R.L.,Ramirez D.M.O.,Hammer R.E.,Hamra F.K.,Matern S.,Russell D.W.

Mutation of beta-glucosidase 2 causes glycolipid storage disease and impaired male fertility.

J. Clin. Invest.

116

2985-2994

2006

802022

Huttlin E.L.,Jedrychowski M.P.,Elias J.E.,Goswami T.,Rad R.,Beausoleil S.A.,Villen J.,Haas W.,Sowa M.E.,Gygi S.P.

A tissue-specific atlas of mouse protein phosphorylation and expression.

Cell

143

1174-1189

2010

802023

Korschen H.G.,Yildiz Y.,Raju D.N.,Schonauer S.,Bonigk W.,Jansen V.,Kremmer E.,Kaupp U.B.,Wachten D.

The non-lysosomal beta-glucosidase GBA2 is a non-integral membrane-associated protein at the endoplasmic reticulum (ER) and Golgi.

J. Biol. Chem.

288

3381-3393

2013

802024

Raju D.,Schonauer S.,Hamzeh H.,Flynn K.C.,Bradke F.,Vom Dorp K.,Doermann P.,Yildiz Y.,Troetschel C.,Poetsch A.,Breiden B.,Sandhoff K.,Koerschen H.G.,Wachten D.

Accumulation of glucosylceramide in the absence of the beta-glucosidase GBA2 alters cytoskeletal dynamics.

PLoS Genet.

11

0-0

2015

802025

Marques A.R.,Mirzaian M.,Akiyama H.,Wisse P.,Ferraz M.J.,Gaspar P.,Ghauharali-van der Vlugt K.,Meijer R.,Giraldo P.,Alfonso P.,Irun P.,Dahl M.,Karlsson S.,Pavlova E.V.,Cox T.M.,Scheij S.,Verhoek M.,Ottenhoff R.,van Roomen C.P.,Pannu N.S.,van Eijk M.,Dekker N.,Boot R.G.,Overkleeft H.S.,Blommaart E.,Hirabayashi Y.,Aerts J.M.

Glucosylated cholesterol in mammalian cells and tissues: formation and degradation by multiple cellular beta-glucosidases.

J. Lipid Res.

57

451-463

2016

802026

Schonauer S.,Koerschen H.G.,Penno A.,Rennhack A.,Breiden B.,Sandhoff K.,Gutbrod K.,Doermann P.,Raju D.N.,Haberkant P.,Gerl M.J.,Bruegger B.,Zigdon H.,Vardi A.,Futerman A.H.,Thiele C.,Wachten D.

Identification of a feedback loop involving beta-glucosidase 2 and its product sphingosine sheds light on the molecular mechanisms in Gaucher disease.

J. Biol. Chem.

292

6177-6189

2017

802027

Akiyama H.,Ide M.,Nagatsuka Y.,Sayano T.,Nakanishi E.,Uemura N.,Yuyama K.,Yamaguchi Y.,Kamiguchi H.,Takahashi R.,Aerts J.M.F.G.,Greimel P.,Hirabayashi Y.

Glucocerebrosidases catalyze a transgalactosylation reaction that yields a newly-identified brain sterol metabolite, galactosylated cholesterol.

J. Biol. Chem.

295

5257-5277

2020