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Sequence of DPOL_PYRFU

EC Number:2.7.7.7

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
DNA-directed DNA polymerase
P61875
Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)
775
90113
Reaction
a 2'-deoxyribonucleoside 5'-triphosphate + DNAn = diphosphate + DNAn+1
Other sequences found for EC No. 2.7.7.7

General information:

Sequence
show sequence in fasta format
  0 MILDVDYITE EGKPVIRLFK KENGKFKIEH DRTFRPYIYA LLRDDSKIEE VKKITGERHG
 60 KIVRIVDVEK VEKKFLGKPI TVWKLYLEHP QDVPTIREKV REHPAVVDIF EYDIPFAKRY
120 LIDKGLIPME GEEELKILAF DIETLYHEGE EFGKGPIIMI SYADENEAKV ITWKNIDLPY
180 VEVVSSEREM IKRFLRIIRE KDPDIIVTYN GDSFDFPYLA KRAEKLGIKL TIGRDGSEPK
240 MQRIGDMTAV EVKGRIHFDL YHVITRTINL PTYTLEAVYE AIFGKPKEKV YADEIAKAWE
300 SGENLERVAK YSMEDAKATY ELGKEFLPME IQLSRLVGQP LWDVSRSSTG NLVEWFLLRK
360 AYERNEVAPN KPSEEEYQRR LRESYTGGFV KEPEKGLWEN IVYLDFRALY PSIIITHNVS
420 PDTLNLEGCK NYDIAPQVGH KFCKDIPGFI PSLLGHLLEE RQKIKTKMKE TQDPIEKILL
480 DYRQKAIKLL ANSFYGYYGY AKARWYCKEC AESVTAWGRK YIELVWKELE EKFGFKVLYI
540 DTDGLYATIP GGESEEIKKK ALEFVKYINS KLPGLLELEY EGFYKRGFFV TKKRYAVIDE
600 EGKVITRGLE IVRRDWSEIA KETQARVLET ILKHGDVEEA VRIVKEVIQK LANYEIPPEK
660 LAIYEQITRP LHEYKAIGPH VAVAKKLAAK GVKIKPGMVI GYIVLRGDGP ISNRAILAEE
720 YDPKKHKYDA EYYIENQVLP AVLRILEGFG YRKEDLRYQK TRQVGLTSWL NIKKS
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
791592
Uemori T.,Ishino Y.,Toh H.,Asada F.,Kato I.
Organization and nucleotide sequence of the DNA polymerase gene from the archaeon Pyrococcus furiosus.
Nucleic Acids Res.
21
259-265
1993
791593
Maeder D.L.,Weiss R.B.,Dunn D.M.,Cherry J.L.,Gonzalez J.M.,DiRuggiero J.,Robb F.T.
Divergence of the hyperthermophilic archaea Pyrococcus furiosus and P. horikoshii inferred from complete genomic sequences.
Genetics
152
1299-1305
1999
791594
Mathur E.J.,Adams M.W.W.,Callen W.N.,Cline J.M.
The DNA polymerase gene from the hyperthermophilic marine archaebacterium, Pyrococcus furiosus, shows sequence homology with alpha-like DNA polymerases.
Nucleic Acids Res.
19
6952-6952
1991
791596
Forterre P.
The DNA polymerase from the archaebacterium Pyrococcus furiosus does not testify for a specific relationship between archaebacteria and eukaryotes.
Nucleic Acids Res.
20
1811-1811
1992
791597
Matsumiya S.,Ishino S.,Ishino Y.,Morikawa K.
Physical interaction between proliferating cell nuclear antigen and replication factor C from Pyrococcus furiosus.
Genes Cells
7
911-922
2002
791598
Kim S.W.,Kim D.U.,Kim J.K.,Kang L.W.,Cho H.S.
Crystal structure of Pfu, the high fidelity DNA polymerase from Pyrococcus furiosus.
Int. J. Biol. Macromol.
42
356-361
2008
791600
Wynne S.A.,Pinheiro V.B.,Holliger P.,Leslie A.G.
Structures of an apo and a binary complex of an evolved archeal B family DNA polymerase capable of synthesising highly cy-dye labelled DNA.
PLoS ONE
8
0-0
2013