Any feedback?
Please rate this page
(sequences.php)
(0/150)

BRENDA support

Sequence of DNAS1_BOVIN

EC Number:3.1.21.1

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
deoxyribonuclease I
P00639
Bos taurus
282
31346
Reaction
endonucleolytic cleavage to 5'-phosphodinucleotide and 5'-phosphooligonucleotide end-products
Other sequences found for EC No. 3.1.21.1

General information:

Sequence
show sequence in fasta format
  0 MRGTRLMGLL LALAGLLQLG LSLKIAAFNI RTFGETKMSN ATLASYIVRI VRRYDIVLIQ
 60 EVRDSHLVAV GKLLDYLNQD DPNTYHYVVS EPLGRNSYKE RYLFLFRPNK VSVLDTYQYD
120 DGCESCGNDS FSREPAVVKF SSHSTKVKEF AIVALHSAPS DAVAEINSLY DVYLDVQQKW
180 HLNDVMLMGD FNADCSYVTS SQWSSIRLRT SSTFQWLIPD SADTTATSTN CAYDRIVVAG
240 SLLQSSVVPG SAAPFDFQAA YGLSNEMALA ISDHYPVEVT LT
Download this sequence
in fasta format
Download all sequences for 3.1.21.1
in fasta format
in csv (Excel, OpenOffice) format
Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
790775
Chen C.Y.,Lu S.C.,Liao T.H.
Cloning, sequencing and expression of a cDNA encoding bovine pancreatic deoxyribonuclease I in Escherichia coli: purification and characterization of the recombinant enzyme.
Gene
206
181-184
1998
790776
De Maria A.,Arruti C.
Bovine DNase I: gene organization, mRNA expression, and changes in the topological distribution of the protein during apoptosis in lens epithelial cells.
Biochem. Biophys. Res. Commun.
312
634-641
2003
790778
Liao T.-H.,Salnikow J.,Moore S.,Stein W.H.
Bovine pancreatic deoxyribonuclease A. Isolation of cyanogen bromide peptides; complete covalent structure of the polypeptide chain.
J. Biol. Chem.
248
1489-1495
1973
790779
Liao T.-H.,Salnikow J.,Moore S.,Stein W.H.
J. Biol. Chem.
267
7957-7957
1992
790780
Salnikow J.,Murphy D.
Bovine pancreatic deoxyribonucleases A and C. A proline for histidine substitution in deoxyribonuclease C.
J. Biol. Chem.
248
1499-1501
1973
790781
Liao T.-H.
Bovine pancreatic deoxyribonuclease D.
J. Biol. Chem.
249
2354-2356
1974
790782
Price P.A.,Moore S.,Stein W.H.
Alkylation of a histidine residue at the active site of bovine pancreatic deoxyribonuclease.
J. Biol. Chem.
244
924-928
1969
790783
Hugli T.E.,Stein W.H.
Involvement of a tyrosine residue in the activity of bovine pancreatic deoxyribonuclease A.
J. Biol. Chem.
246
7191-7200
1971
790784
Suck D.,Oefner C.
Structure of DNase I at 2.0-A resolution suggests a mechanism for binding to and cutting DNA.
Nature
321
620-625
1986
790785
Oefner C.,Suck D.
Crystallographic refinement and structure of DNase I at 2-A resolution.
J. Mol. Biol.
192
605-632
1986
790786
Suck D.,Lahm A.,Oefner C.
Structure refined to 2 A of a nicked DNA octanucleotide complex with DNase I.
Nature
332
464-468
1988
790787
Lahm A.,Suck D.
DNase I-induced DNA conformation. 2-A structure of a DNase I-octamer complex.
J. Mol. Biol.
222
645-667
1991
790788
Weston S.A.,Lahm A.,Suck D.
X-ray structure of the DNase I-d(GGTATACC)2 complex at 2.3-A resolution.
J. Mol. Biol.
226
1237-1256
1992
790789
Kabsch W.,Mannherz H.G.,Suck D.,Pai E.F.,Holmes K.C.
Atomic structure of the actin:DNase I complex.
Nature
347
37-44
1990