Sequence of SPHK1_MOUSE

sphingosine kinase

Q8CI15

382

42443

739329

Kohama T.,Olivera A.,Edsall L.,Nagiec M.M.,Dickson R.,Spiegel S.

Molecular cloning and functional characterization of murine sphingosine kinase.

J. Biol. Chem.

273

23722-23728

1998

739331

Carninci P.,Kasukawa T.,Katayama S.,Gough J.,Frith M.C.,Maeda N.,Oyama R.,Ravasi T.,Lenhard B.,Wells C.,Kodzius R.,Shimokawa K.,Bajic V.B.,Brenner S.E.,Batalov S.,Forrest A.R.,Zavolan M.,Davis M.J.,Wilming L.G.,Aidinis V.,Allen J.E.,Ambesi-Impiombato A.,Apweiler R.,Aturaliya R.N.,Bailey T.L.,Bansal M.,Baxter L.,Beisel K.W.,Bersano T.,Bono H.,Chalk A.M.,Chiu K.P.,Choudhary V.,Christoffels A.,Clutterbuck D.R.,Crowe M.L.,Dalla E.,Dalrymple B.P.,de Bono B.,Della Gatta G.,di Bernardo D.,Down T.,Engstrom P.,Fagiolini M.,Faulkner G.,Fletcher C.F.,Fukushima T.,Furuno M.,Futaki S.,Gariboldi M.,Georgii-Hemming P.,Gingeras T.R.,Gojobori T.,Green R.E.,Gustincich S.,Harbers M.,Hayashi Y.,Hensch T.K.,Hirokawa N.,Hill D.,Huminiecki L.,Iacono M.,Ikeo K.,Iwama A.,Ishikawa T.,Jakt M.,Kanapin A.,Katoh M.,Kawasawa Y.,Kelso J.,Kitamura H.,Kitano H.,Kollias G.,Krishnan S.P.,Kruger A.,Kummerfeld S.K.,Kurochkin I.V.,Lareau L.F.,Lazarevic D.,Lipovich L.,Liu J.,Liuni S.,McWilliam S.,Madan Babu M.,Madera M.,Marchionni L.,Matsuda H.,Matsuzawa S.,Miki H.,Mignone F.,Miyake S.,Morris K.,Mottagui-Tabar S.,Mulder N.,Nakano N.,Nakauchi H.,Ng P.,Nilsson R.,Nishiguchi S.,Nishikawa S.,Nori F.,Ohara O.,Okazaki Y.,Orlando V.,Pang K.C.,Pavan W.J.,Pavesi G.,Pesole G.,Petrovsky N.,Piazza S.,Reed J.,Reid J.F.,Ring B.Z.,Ringwald M.,Rost B.,Ruan Y.,Salzberg S.L.,Sandelin A.,Schneider C.,Schoenbach C.,Sekiguchi K.,Semple C.A.,Seno S.,Sessa L.,Sheng Y.,Shibata Y.,Shimada H.,Shimada K.,Silva D.,Sinclair B.,Sperling S.,Stupka E.,Sugiura K.,Sultana R.,Takenaka Y.,Taki K.,Tammoja K.,Tan S.L.,Tang S.,Taylor M.S.,Tegner J.,Teichmann S.A.,Ueda H.R.,van Nimwegen E.,Verardo R.,Wei C.L.,Yagi K.,Yamanishi H.,Zabarovsky E.,Zhu S.,Zimmer A.,Hide W.,Bult C.,Grimmond S.M.,Teasdale R.D.,Liu E.T.,Brusic V.,Quackenbush J.,Wahlestedt C.,Mattick J.S.,Hume D.A.,Kai C.,Sasaki D.,Tomaru Y.,Fukuda S.,Kanamori-Katayama M.,Suzuki M.,Aoki J.,Arakawa T.,Iida J.,Imamura K.,Itoh M.,Kato T.,Kawaji H.,Kawagashira N.,Kawashima T.,Kojima M.,Kondo S.,Konno H.,Nakano K.,Ninomiya N.,Nishio T.,Okada M.,Plessy C.,Shibata K.,Shiraki T.,Suzuki S.,Tagami M.,Waki K.,Watahiki A.,Okamura-Oho Y.,Suzuki H.,Kawai J.,Hayashizaki Y.

The transcriptional landscape of the mammalian genome.

Science

309

1559-1563

2005

739332

Church D.M.,Goodstadt L.,Hillier L.W.,Zody M.C.,Goldstein S.,She X.,Bult C.J.,Agarwala R.,Cherry J.L.,DiCuccio M.,Hlavina W.,Kapustin Y.,Meric P.,Maglott D.,Birtle Z.,Marques A.C.,Graves T.,Zhou S.,Teague B.,Potamousis K.,Churas C.,Place M.,Herschleb J.,Runnheim R.,Forrest D.,Amos-Landgraf J.,Schwartz D.C.,Cheng Z.,Lindblad-Toh K.,Eichler E.E.,Ponting C.P.

Lineage-specific biology revealed by a finished genome assembly of the mouse.

PLoS Biol.

7

0-0

2009

739333

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

Genome Res.

14

2121-2127

2004

739334

Maceyka M.,Nava V.E.,Milstien S.,Spiegel S.

Aminoacylase 1 is a sphingosine kinase 1-interacting protein.

FEBS Lett.

568

30-34

2004

739335

Allende M.L.,Sasaki T.,Kawai H.,Olivera A.,Mi Y.,van Echten-Deckert G.,Hajdu R.,Rosenbach M.,Keohane C.A.,Mandala S.,Spiegel S.,Proia R.L.

Mice deficient in sphingosine kinase 1 are rendered lymphopenic by FTY720.

J. Biol. Chem.

279

52487-52492

2004

739336

Maceyka M.,Sankala H.,Hait N.C.,Le Stunff H.,Liu H.,Toman R.,Collier C.,Zhang M.,Satin L.S.,Merrill A.H. Jr.,Milstien S.,Spiegel S.

SphK1 and SphK2, sphingosine kinase isoenzymes with opposing functions in sphingolipid metabolism.

J. Biol. Chem.

280

37118-37129

2005

739337

Mizugishi K.,Yamashita T.,Olivera A.,Miller G.F.,Spiegel S.,Proia R.L.

Essential role for sphingosine kinases in neural and vascular development.

Mol. Cell. Biol.

25

11113-11121

2005

739338

Olivera A.,Mizugishi K.,Tikhonova A.,Ciaccia L.,Odom S.,Proia R.L.,Rivera J.

The sphingosine kinase-sphingosine-1-phosphate axis is a determinant of mast cell function and anaphylaxis.

Immunity

26

287-297

2007

739339

Hisano Y.,Kobayashi N.,Kawahara A.,Yamaguchi A.,Nishi T.

The sphingosine 1-phosphate transporter, SPNS2, functions as a transporter of the phosphorylated form of the immunomodulating agent FTY720.

J. Biol. Chem.

286

1758-1766

2011

739340

Shen H.,Giordano F.,Wu Y.,Chan J.,Zhu C.,Milosevic I.,Wu X.,Yao K.,Chen B.,Baumgart T.,Sieburth D.,De Camilli P.

Coupling between endocytosis and sphingosine kinase 1 recruitment.

Nat. Cell Biol.

16

652-662

2014

739341

Lee H.,Lee J.K.,Park M.H.,Hong Y.R.,Marti H.H.,Kim H.,Okada Y.,Otsu M.,Seo E.J.,Park J.H.,Bae J.H.,Okino N.,He X.,Schuchman E.H.,Bae J.S.,Jin H.K.

Pathological roles of the VEGF/SphK pathway in Niemann-Pick type C neurons.

Nat. Commun.

5

5514-5514

2014

739342

Young M.M.,Takahashi Y.,Fox T.E.,Yun J.K.,Kester M.,Wang H.G.

Sphingosine Kinase 1 Cooperates with Autophagy to Maintain Endocytic Membrane Trafficking.

Cell Rep.

17

1532-1545

2016

739343

Lima S.,Milstien S.,Spiegel S.

Sphingosine and Sphingosine Kinase 1 Involvement in Endocytic Membrane Trafficking.

J. Biol. Chem.

292

3074-3088

2017

739344

Lee J.Y.,Han S.H.,Park M.H.,Baek B.,Song I.S.,Choi M.K.,Takuwa Y.,Ryu H.,Kim S.H.,He X.,Schuchman E.H.,Bae J.S.,Jin H.K.

Neuronal SphK1 acetylates COX2 and contributes to pathogenesis in a model of Alzheimer's Disease.

Nat. Commun.

9

1479-1479

2018

739345

Nguyen T.Q.,Vu T.M.,Tukijan F.,Muralidharan S.,Foo J.C.,Li Chin J.F.,Hasan Z.,Torta F.,Nguyen L.N.

Erythrocytes efficiently utilize exogenous sphingosines for S1P synthesis and export via Mfsd2b.

J. Biol. Chem.

296

100201-100201

2021