Sequence of P4HA1_CAEEL
EC Number:1.14.11.2
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
procollagen L-proline + 2-oxoglutarate + O2 = procollagen trans-4-hydroxy-L-proline + succinate + CO2
General information:
Sequence
0 MRLALLVLAT IGYAVADLFT SIADMQNLLE TERNIPKILD KYIHDEEERL VQLKKLSEEY
60 SKKNEISIEN GLKDITNPIN AFLLIKRKIF DWKEIESKMN ANKAGNVVSS ITDDSYGVRY
120 PTADDLSGAA IGLLRLQDTY RLDTKDLADG KIYADQGNYT FSAKDCFEIA RAAYNEHDFY
180 HTVMWMEEAQ RRLGDEVEPT VEVEDILEYL AFALYKQNNL KHALKLTEEL YKMNPTHPRA
240 KGNVKWYEDL LEQEGVRRSD MRKNLPPIQN RRPDSVLGNT ERTMYEALCR NEVPVSQKDI
300 SRLYCYYKRD RPFLVYAPIK VEIKRFNPLA VLFKDVISDD EVAAIQELAK PKLARATVHD
360 SVTGKLVTAT YRISKSAWLK EWEGDVVETV NKRIGYMTNL EMETAEELQI ANYGIGGHYD
420 PHFDHAKKEE SKSFESLGTG NRIATVLFYM SQPSHGGGTV FTEAKSTILP TKNDALFWYN
480 LYKQGDGNPD TRHAACPVLV GIKWVSNKWI HEKGNEFRRP CGLKSSDYER FVGDLGYGPE
540 PRNAPNVSPN LAKDVWETL
Download this sequence
in fasta formatDownload all sequences for 1.14.11.2
in fasta format
in csv (Excel, OpenOffice) formatSequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
726668
Veijola J.,Koivunen P.,Annunen P.,Pihlajaniemi T.,Kivirikko K.I.
Cloning, baculovirus expression, and characterization of the alpha subunit of prolyl 4-hydroxylase from the nematode Caenorhabditis elegans. This alpha subunit forms an active alpha beta dimer with the human protein disulfide isomerase/beta subunit.
J. Biol. Chem.
269
26746-26753
1994
726669
Winter A.D.,Page A.P.
Prolyl 4-hydroxylase is an essential procollagen-modifying enzyme required for exoskeleton formation and the maintenance of body shape in the nematode Caenorhabditis elegans.
Mol. Cell. Biol.
20
4084-4093
2000
726670
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science
282
2012-2018
1998
726671
Myllyharju J.,Kukkola L.,Winter A.D.,Page A.P.
The exoskeleton collagens in Caenorhabditis elegans are modified by prolyl 4-hydroxylases with unique combinations of subunits.
J. Biol. Chem.
277
29187-29196
2002
726672
Kaji H.,Saito H.,Yamauchi Y.,Shinkawa T.,Taoka M.,Hirabayashi J.,Kasai K.,Takahashi N.,Isobe T.
Lectin affinity capture, isotope-coded tagging and mass spectrometry to identify N-linked glycoproteins.
Nat. Biotechnol.
21
667-672
2003
726673
Kaji H.,Kamiie J.,Kawakami H.,Kido K.,Yamauchi Y.,Shinkawa T.,Taoka M.,Takahashi N.,Isobe T.
Proteomics reveals N-linked glycoprotein diversity in Caenorhabditis elegans and suggests an atypical translocation mechanism for integral membrane proteins.
Mol. Cell. Proteomics
6
2100-2109
2007
