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Sequence of S27A4_MOUSE

EC Number:6.2.1.3

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
long-chain-fatty-acid-CoA ligase
Q91VE0
Mus musculus
643
72319
Reaction
ATP + a long-chain fatty acid + CoA = AMP + diphosphate + a long-chain fatty acyl-CoA
Other sequences found for EC No. 6.2.1.3

General information:

Sequence
show sequence in fasta format
  0 MLLGASLVGA LLFSKLVLKL PWTQVGFSLL LLYLGSGGWR FIRVFIKTVR RDIFGGMVLL
 60 KVKTKVRRYL QERKTVPLLF ASMVQRHPDK TALIFEGTDT HWTFRQLDEY SSSVANFLQA
120 RGLASGNVVA LFMENRNEFV GLWLGMAKLG VEAALINTNL RRDALRHCLD TSKARALIFG
180 SEMASAICEI HASLEPTLSL FCSGSWEPST VPVSTEHLDP LLEDAPKHLP SHPDKGFTDK
240 LFYIYTSGTT GLPKAAIVVH SRYYRMASLV YYGFRMRPDD IVYDCLPLYH SAGNIVGIGQ
300 CLLHGMTVVI RKKFSASRFW DDCIKYNCTI VQYIGELCRY LLNQPPREAE SRHKVRMALG
360 NGLRQSIWTD FSSRFHIPQV AEFYGATECN CSLGNFDSRV GACGFNSRIL SFVYPIRLVR
420 VNEDTMELIR GPDGVCIPCQ PGQPGQLVGR IIQQDPLRRF DGYLNQGANN KKIANDVFKK
480 GDQAYLTGDV LVMDELGYLY FRDRTGDTFR WKGENVSTTE VEGTLSRLLH MADVAVYGVE
540 VPGTEGRAGM AAVASPISNC DLESFAQTLK KELPLYARPI FLRFLPELHK TGTFKFQKTE
600 LRKEGFDPSV VKDPLFYLDA RKGCYVALDQ EAYTRIQAGE EKL
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
608247
Herrmann T.,Buchkremer F.,Gosch I.,Hall A.M.,Bernlohr D.A.,Stremmel W.
Mouse fatty acid transport protein 4 (FATP4): characterization of the gene and functional assessment as a very long chain acyl-CoA synthetase.
Gene
270
31-40
2001
608248
Carninci P.,Kasukawa T.,Katayama S.,Gough J.,Frith M.C.,Maeda N.,Oyama R.,Ravasi T.,Lenhard B.,Wells C.,Kodzius R.,Shimokawa K.,Bajic V.B.,Brenner S.E.,Batalov S.,Forrest A.R.,Zavolan M.,Davis M.J.,Wilming L.G.,Aidinis V.,Allen J.E.,Ambesi-Impiombato A.,Apweiler R.,Aturaliya R.N.,Bailey T.L.,Bansal M.,Baxter L.,Beisel K.W.,Bersano T.,Bono H.,Chalk A.M.,Chiu K.P.,Choudhary V.,Christoffels A.,Clutterbuck D.R.,Crowe M.L.,Dalla E.,Dalrymple B.P.,de Bono B.,Della Gatta G.,di Bernardo D.,Down T.,Engstrom P.,Fagiolini M.,Faulkner G.,Fletcher C.F.,Fukushima T.,Furuno M.,Futaki S.,Gariboldi M.,Georgii-Hemming P.,Gingeras T.R.,Gojobori T.,Green R.E.,Gustincich S.,Harbers M.,Hayashi Y.,Hensch T.K.,Hirokawa N.,Hill D.,Huminiecki L.,Iacono M.,Ikeo K.,Iwama A.,Ishikawa T.,Jakt M.,Kanapin A.,Katoh M.,Kawasawa Y.,Kelso J.,Kitamura H.,Kitano H.,Kollias G.,Krishnan S.P.,Kruger A.,Kummerfeld S.K.,Kurochkin I.V.,Lareau L.F.,Lazarevic D.,Lipovich L.,Liu J.,Liuni S.,McWilliam S.,Madan Babu M.,Madera M.,Marchionni L.,Matsuda H.,Matsuzawa S.,Miki H.,Mignone F.,Miyake S.,Morris K.,Mottagui-Tabar S.,Mulder N.,Nakano N.,Nakauchi H.,Ng P.,Nilsson R.,Nishiguchi S.,Nishikawa S.,Nori F.,Ohara O.,Okazaki Y.,Orlando V.,Pang K.C.,Pavan W.J.,Pavesi G.,Pesole G.,Petrovsky N.,Piazza S.,Reed J.,Reid J.F.,Ring B.Z.,Ringwald M.,Rost B.,Ruan Y.,Salzberg S.L.,Sandelin A.,Schneider C.,Schoenbach C.,Sekiguchi K.,Semple C.A.,Seno S.,Sessa L.,Sheng Y.,Shibata Y.,Shimada H.,Shimada K.,Silva D.,Sinclair B.,Sperling S.,Stupka E.,Sugiura K.,Sultana R.,Takenaka Y.,Taki K.,Tammoja K.,Tan S.L.,Tang S.,Taylor M.S.,Tegner J.,Teichmann S.A.,Ueda H.R.,van Nimwegen E.,Verardo R.,Wei C.L.,Yagi K.,Yamanishi H.,Zabarovsky E.,Zhu S.,Zimmer A.,Hide W.,Bult C.,Grimmond S.M.,Teasdale R.D.,Liu E.T.,Brusic V.,Quackenbush J.,Wahlestedt C.,Mattick J.S.,Hume D.A.,Kai C.,Sasaki D.,Tomaru Y.,Fukuda S.,Kanamori-Katayama M.,Suzuki M.,Aoki J.,Arakawa T.,Iida J.,Imamura K.,Itoh M.,Kato T.,Kawaji H.,Kawagashira N.,Kawashima T.,Kojima M.,Kondo S.,Konno H.,Nakano K.,Ninomiya N.,Nishio T.,Okada M.,Plessy C.,Shibata K.,Shiraki T.,Suzuki S.,Tagami M.,Waki K.,Watahiki A.,Okamura-Oho Y.,Suzuki H.,Kawai J.,Hayashizaki Y.
The transcriptional landscape of the mammalian genome.
Science
309
1559-1563
2005
608250
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Genome Res.
14
2121-2127
2004
608251
Hirsch D.,Stahl A.,Lodish H.F.
A family of fatty acid transporters conserved from mycobacterium to man.
Proc. Natl. Acad. Sci. U.S.A.
95
8625-8629
1998
608252
Stahl A.,Hirsch D.J.,Gimeno R.E.,Punreddy S.,Ge P.,Watson N.,Patel S.,Kotler M.,Raimondi A.,Tartaglia L.A.,Lodish H.F.
Identification of the major intestinal fatty acid transport protein.
Mol. Cell
4
299-308
1999
608253
Gimeno R.E.,Hirsch D.J.,Punreddy S.,Sun Y.,Ortegon A.M.,Wu H.,Daniels T.,Stricker-Krongrad A.,Lodish H.F.,Stahl A.
Targeted deletion of fatty acid transport protein-4 results in early embryonic lethality.
J. Biol. Chem.
278
49512-49516
2003
608254
Herrmann T.,van der Hoeven F.,Grone H.J.,Stewart A.F.,Langbein L.,Kaiser I.,Liebisch G.,Gosch I.,Buchkremer F.,Drobnik W.,Schmitz G.,Stremmel W.
Mice with targeted disruption of the fatty acid transport protein 4 (Fatp 4, Slc27a4) gene show features of lethal restrictive dermopathy.
J. Cell Biol.
161
1105-1115
2003
608255
Moulson C.L.,Martin D.R.,Lugus J.J.,Schaffer J.E.,Lind A.C.,Miner J.H.
Cloning of wrinkle-free, a previously uncharacterized mouse mutation, reveals crucial roles for fatty acid transport protein 4 in skin and hair development.
Proc. Natl. Acad. Sci. U.S.A.
100
5274-5279
2003
608256
Hall A.M.,Wiczer B.M.,Herrmann T.,Stremmel W.,Bernlohr D.A.
Enzymatic properties of purified murine fatty acid transport protein 4 and analysis of acyl-CoA synthetase activities in tissues from FATP4 null mice.
J. Biol. Chem.
280
11948-11954
2005
608257
DiRusso C.C.,Li H.,Darwis D.,Watkins P.A.,Berger J.,Black P.N.
Comparative biochemical studies of the murine fatty acid transport proteins (FATP) expressed in yeast.
J. Biol. Chem.
280
16829-16837
2005
608258
Trinidad J.C.,Specht C.G.,Thalhammer A.,Schoepfer R.,Burlingame A.L.
Comprehensive identification of phosphorylation sites in postsynaptic density preparations.
Mol. Cell. Proteomics
5
914-922
2006
608259
Huttlin E.L.,Jedrychowski M.P.,Elias J.E.,Goswami T.,Rad R.,Beausoleil S.A.,Villen J.,Haas W.,Sowa M.E.,Gygi S.P.
A tissue-specific atlas of mouse protein phosphorylation and expression.
Cell
143
1174-1189
2010
608260
Zhou W.,Madrid P.,Fluitt A.,Stahl A.,Xie X.S.
Development and validation of a high-throughput screening assay for human long-chain fatty acid transport proteins 4 and 5.
J. Biomol. Screen.
15
488-497
2010
608261
Li S.,Lee J.,Zhou Y.,Gordon W.C.,Hill J.M.,Bazan N.G.,Miner J.H.,Jin M.
Fatty acid transport protein 4 (FATP4) prevents light-induced degeneration of cone and rod photoreceptors by inhibiting RPE65 isomerase.
J. Neurosci.
33
3178-3189
2013