Sequence of LEU1_CORGL
EC Number:2.3.3.13
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
2-isopropylmalate synthase
P42455
Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025)
616
68188
Reaction
acetyl-CoA + 3-methyl-2-oxobutanoate + H2O = (2S)-2-isopropylmalate + CoA
Other sequences found for EC No. 2.3.3.13
General information:
Sequence
0 MSPNDAFISA PAKIETPVGP RNEGQPAWNK QRGSSMPVNR YMPFEVEVED ISLPDRTWPD
60 KKITVAPQWC AVDLRDGNQA LIDPMSPERK RRMFELLVQM GFKEIEVGFP SASQTDFDFV
120 REIIEKGMIP DDVTIQVLVQ AREHLIRRTF EACEGAKNVI VHFYNSTSIL QRNVVFRMDK
180 VQVKKLATDA AELIKTIAQD YPDTNWRWQY SPESFTGTEV EYAKEVVDAV VEVMDPTPEN
240 PMIINLPSTV EMITPNVYAD SIEWMHRNLN RRDSIILSLH PHNDRGTGVG AAELGYMAGA
300 DRIEGCLFGN GERTGNVCLV TLALNMLTQG VDPQLDFTDI RQIRSTVEYC NQLRVPERHP
360 YGGDLVFTAF SGSHQDAVNK GLDAMAAKVQ PGASSTEVSW EQLRDTEWEV PYLPIDPKDV
420 GRDYEAVIRV NSQSGKGGVA YIMKTDHGLQ IPRSMQVEFS TVVQNVTDAE GGEVNSKAMW
480 DIFATEYLER TAPVEQIALR VENAQTENED ASITAELIHN GKDVTVDGRG NGPLAAYANA
540 LEKLGIDVEI QEYNQHARTS GDDAEAAAYV LAEVNGRKVW GVGIAGSITY ASLKAVTSAV
600 NRALDVNHEA VLAGGV
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
53411
Patek M.,Krumbach K.,Eggeling L.,Sahm H.
Leucine synthesis in Corynebacterium glutamicum: enzyme activities, structure of leuA, and effect of leuA inactivation on lysine synthesis.
Appl. Environ. Microbiol.
60
133-140
1994
53412
Ikeda M.,Nakagawa S.
The Corynebacterium glutamicum genome: features and impacts on biotechnological processes.
Appl. Microbiol. Biotechnol.
62
99-109
2003
53413
Kalinowski J.,Bathe B.,Bartels D.,Bischoff N.,Bott M.,Burkovski A.,Dusch N.,Eggeling L.,Eikmanns B.J.,Gaigalat L.,Goesmann A.,Hartmann M.,Huthmacher K.,Kraemer R.,Linke B.,McHardy A.C.,Meyer F.,Moeckel B.,Pfefferle W.,Puehler A.,Rey D.A.,Rueckert C.,Rupp O.,Sahm H.,Wendisch V.F.,Wiegraebe I.,Tauch A.
The complete Corynebacterium glutamicum ATCC 13032 genome sequence and its impact on the production of L-aspartate-derived amino acids and vitamins.
J. Biotechnol.
104
5-25
2003
