Sequence of NOS2_RAT
EC Number:1.14.13.39
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
2 L-arginine + 2 NADPH + 2 H+ + 2 O2 = 2 Nomega-hydroxy-L-arginine + 2 NADP+ + 2 H2O
Other sequences found for EC No. 1.14.13.39
General information:
Sequence
0 MACPWKFLFR VKSYQGDLKE EKDINNNVEK TPGAIPSPTT QDDPKSHKHQ NGFPQFLTGT
60 AQNVPESLDK LHVTPSTRPQ HVRIKNWGNG EIFHDTLHHK ATSDISCKSK LCMGSIMNSK
120 SLTRGPRDKP TPVEELLPQA IEFINQYYGS FKEAKIEEHL ARLEAVTKEI ETTGTYQLTL
180 DELIFATKMA WRNAPRCIGR IQWSNLQVFD ARSCSTASEM FQHICRHILY ATNSGNIRSA
240 ITVFPQRSDG KHDFRIWNSQ LIRYAGYQMP DGTIRGDPAT LEFTQLCIDL GWKPRYGRFD
300 VLPLVLQAHG QDPEVFEIPP DLVLEVTMEH PKYEWFQELG LKWYALPAVA NMLLEVGGLE
360 FPACPFNGWY MGTEIGVRDF CDTQRYNILE EVGRRMGLET HTLASLWKDR AVTEINAAVL
420 HSFQKQNVTI MDHHTASESF MKHMQNEYRA RGGCPADWIW LVPPVSGSIT PVFHQEMLNY
480 VLSPFYYYQI EPWKTHIWQD EKLRPRRREI RFTVLVKAVF FASVLMRKVM ASRVRATVLF
540 ATETGKSEAL ARDLAALFSY AFNTKVVCME QYKANTLEEE QLLLVVTSTF GNGDCPSNGQ
600 TLKKSLFMMK ELGHTFRYAV FGLGSSMYPQ FCAFAHDIDQ KLSHLGASQL APTGEGDELS
660 GQEDAFRSWA VQTFRAACET FDVRSKHCIQ IPKRYTSNAT WEPEQYKLTQ SPESLDLNKA
720 LSSIHAKNVF TMRLKSLQNL QSEKSSRTTL LVQLTFEGSR GPSYLPGEHL GIFPGNQTAL
780 VQGILERVVD CSSPDQTVCL EVLDESGSYW VKDKRLPPCS LRQALTYFLD ITTPPTQLQL
840 HKLARFATEE THRQRLEALC QPSEYNDWKF SNNPTFLEVL EEFPSLRVPA AFLLSQLPIL
900 KPRYYSISSS QDHTPSEVHL TVAVVTYRTR DGQGPLHHGV CSTWINNLKP EDPVPCFVRS
960 VSGFQLPEDP SQPCILIGPG TGIAPFRSFW QQRLHDSQHR GLKGGRMTLV FGCRHPEEDH
1020 LYQEEMQEMV RKGVLFQVHT GYSRLPGKPK VYVQDILQKE LADEVFSVLH GEQGHLYVCG
1080 DVRMARDVAT TLKKLVAAKL NLSEEQVEDY FFQLKSQKRY HEDIFGAVFS YGAKKGNTLE
1140 EPKGTRL
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
577661
Nunokawa Y.,Ishida N.,Tanaka S.
Cloning of inducible nitric oxide synthase in rat vascular smooth muscle cells.
Biochem. Biophys. Res. Commun.
191
89-94
1993
577662
Karlsen A.E.,Andersen H.U.,Vissing H.,Larsen P.M.,Fey S.J.,Cuartero B.G.,Madsen O.D.,Petersen J.S.,Mortensen S.B.,Mandrup-Poulsen T.,Boel E.,Nerup J.
Cloning and expression of cytokine-inducible nitric oxide synthase cDNA from rat islets of Langerhans.
Diabetes
44
753-758
1995
577663
Galea E.,Reis D.J.,Feinstein D.L.
Cloning and expression of inducible nitric oxide synthase from rat astrocytes.
J. Neurosci. Res.
37
406-414
1994
577664
Adachi H.,Iida S.,Oguchi S.,Ohshima H.,Suzuki H.,Nagasaki K.,Kawasaki H.,Sugimura T.,Esumi H.
Molecular cloning of a cDNA encoding an inducible calmodulin-dependent nitric-oxide synthase from rat liver and its expression in COS 1 cells.
Eur. J. Biochem.
217
37-43
1993
577665
Wood E.R.,Berger H. Jr.,Sherman P.A.,Lapetina E.G.
Hepatocytes and macrophages express an identical cytokine inducible nitric oxide synthase gene.
Biochem. Biophys. Res. Commun.
191
767-774
1993
577666
Geng Y.J.,Almquist M.,Hansson G.K.
cDNA cloning and expression of inducible nitric oxide synthase from rat vascular smooth muscle cells.
Biochim. Biophys. Acta
1218
421-424
1994
577668
Tsutsumishita Y.,Kawai Y.,Takahara H.,Onda T.,Miyoshi J.,Futaki S.,Niwa M.
Sequence analysis of inducible nitric oxide synthase in rat kidney, lung, and uterus.
Biol. Pharm. Bull.
19
1374-1376
1996
577669
Adams V.,Krabbes S.,Jiang H.,Yu J.,Rahmel A.,Gielen S.,Schuler G.,Hambrecht R.
Complete coding sequence of inducible nitric oxide synthase from human heart and skeletal muscle of patients with chronic heart failure.
Nitric Oxide
2
242-249
1998
577670
Chen P.Y.,Gladish R.D.,Sanders P.W.
Vascular smooth muscle nitric oxide synthase anomalies in Dahl/Rapp salt-sensitive rats.
Hypertension
31
918-924
1998
577672
Morrissey J.J.,McCracken R.,Kaneto H.,Vehaskari M.,Montani D.,Klahr S.
Location of an inducible nitric oxide synthase mRNA in the normal kidney.
Kidney Int.
45
998-1005
1994
577674
Hoffert J.D.,Pisitkun T.,Wang G.,Shen R.-F.,Knepper M.A.
Quantitative phosphoproteomics of vasopressin-sensitive renal cells: regulation of aquaporin-2 phosphorylation at two sites.
Proc. Natl. Acad. Sci. U.S.A.
103
7159-7164
2006
