Sequence of MRP2_MOUSE
EC Number:7.6.2.3
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
ATP + H2O + glutathione-S-conjugate[side 1] = ADP + phosphate + glutathione-S-conjugate[side 2]
Other sequences found for EC No. 7.6.2.3
General information:
Sequence
0 MDEFCNSTFW NLSLLKSPEA DLPLCFEQTV LVWIPLGFLW LLAPWQLYRI YRSRTKRFAI
60 TKFYLAKQVF VVCLLILAAI DLSLALTEDT GQATIPPVKY TNPILYLCTW LLVLVIQHCR
120 QCCIQKNSWF LSMFWILSLL CGIFQFQTLI RALLQDSKSN MTYSCLFFVS YGFQIVILIL
180 SAFSESSDST HAPSATASFL SSVTFSWYDS TVLKGYKHPL TIEDVWDIEE NLKAKSLTSK
240 FKTIMTKDLQ KARQALQRRL KKSQQSPEGT SHGLTKKQSQ SQDVLVLEDS KKKKKKSEAT
300 KDFPKSWLVK ALFKTFYVVI LKSFILKLAH DILLFLNPQL LKFLIGFVKD PDSYPWVGYI
360 YAILMFSVTL IQSFFLQCYF QFCFVLGMTV RTTIIASVYK KALTLSNLAR RQYTIGETVN
420 LMSVDSQKLM DVTNYIHLLW SSVLQIALSI FFLWRELGPS ILAGVGLMVL LVPVNGVLAT
480 KIRKIQVQNM KNKDKRLKIM NEILSGIKIL KYFAWEPSFK EQVNSIRKKE LRNLLRFSQL
540 QTILIFILHL TPTLVSVITF SVYVLVDSQN VLNAEKAFTS ITLFNILRFP LAMLPMVISS
600 VIQASVSVDR LEQYLGSDDL DLSAIRHVCH FDKAVQFSEA SFTWDRDLEA TIQDVNLDIK
660 PGQLVAVVGT VGSGKSSLIS AMLGEMENVH GHITIKGSIA YVPQQAWIQN GTIKDNILFG
720 SEYDEKKYQR VIEACALLPD LEMLPGGDMA EIGEKGINLS GGQKHRVSLA RATYQDADIY
780 ILDDPLSAVD THVGKHIFNK VVGPNGLLSG KTRILVTHGI HFLPQVDEIV VLGKGTILEK
840 GSYSDLMDKK GVFAKNWKTF MKHSGPEGEA TVDNDSEEED GDCGLIPTVE EIPDDAASLT
900 MRRENSLRRT LSRSSRSGSR RGKSLKSSLK IKSVNALNKK EEVVKGQKLI KKEFVETGKV
960 KFSIYLKYLQ AVGWWSLLFI VIFYVLNYVA FIGTNLWLSA WTSDSEKQNG TDNSPSQRDM
1020 RIGVFGALGI AQGIFLLSSS LWSIYACRNA SKTLHRQLLT NILRAPMSFF DTTPTGRIVN
1080 RFAGDISTVD DTLPQTLRSW LLCFFGIVST LVMICMATPI FIIIIIPLSI LYVSVQVFYV
1140 ATSRQLRRLD SVTKSPIYSH FSETVSGLPV IRAFEHQQRF LANSEKQIDT NQKCVFSWIT
1200 SNRWLAIRLE LVGNLIVFCS ALLLVIYKNS LTGDTVGFVL SNALNITQTL NWLVRMTSEV
1260 ETNIVAVERI NEYINVDNEA PWVTDKKPPA DWPKKGEIQF NNYQVRYRPE LDLVLKGITC
1320 NIKSTEKVGV VGRTGAGKSS LTNCLFRILE SAGGQIIIDG IDIASIGLHD LRGRLTIIPQ
1380 DPILFSGNLR MNLDPFNKYS DEEIWRALEL AHLKSFVAGL QLGLLHEVTE GGDNLSIGQR
1440 QLLCLGRAVL RKSKILVLDE ATAAVDLETD SLIQTTIRNE FSQCTVITIA HRLHTIMDSD
1500 KIMVLDSGKI VEYGSPEELL SNMGPFYLMA KEAGIESVNH TEL
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
571924
Chu X.Y.,Strauss J.R.,Mariano M.A.,Li J.,Newton D.J.,Cai X.,Wang R.W.,Yabut J.,Hartley D.P.,Evans D.C.,Evers R.
Characterization of mice lacking the multidrug resistance protein MRP2 (ABCC2).
J. Pharmacol. Exp. Ther.
317
579-589
2006
571925
Huttlin E.L.,Jedrychowski M.P.,Elias J.E.,Goswami T.,Rad R.,Beausoleil S.A.,Villen J.,Haas W.,Sowa M.E.,Gygi S.P.
A tissue-specific atlas of mouse protein phosphorylation and expression.
Cell
143
1174-1189
2010
