Sequence of CYP28_STRAW
EC Number:1.14.15.11
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
pentalenic acid synthase
Q825I8
Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680)
402
44113
Reaction
1-deoxypentalenate + reduced ferredoxin + O2 = pentalenate + oxidized ferredoxin + H2O
Other sequences found for EC No. 1.14.15.11
General information:
Sequence
0 MTEPGTSVSA PVAFPQDRTC PYDPPTAYDP LREGRPLSRV SLYDGRSVWV VTGHAAARAL
60 LSDQRLSSDR TLPRFPATTE RFEAVRTRRV ALLGVDDPEH RTQRRMLVPS FTLKRAAALR
120 PRIQETVDGL LDAMEAQGPP AELVSAFALP LPSMVICALL GVPYADHDFF ESQSRRLLRG
180 PGIAEVQDAR AQLDDYLYAL IDRKRKEPGD GLLDDLIQEQ LNRGTVDRAE LVSLATLLLI
240 AGHETTANMI SLGTFTLLRH PEQLAELRAE PGLMPAAVEE LLRFLSIADG LLRVATEDIE
300 VAGTTIRADE GVVFATSVIN RDAAGFAEPD ALDWHRSARH HVAFGFGIHQ CLGQNLARAE
360 MEIALGTLFE RLPGLRLAAP ADEIPFKPGD TIQGMLELPV TW
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
532603
Omura S.,Ikeda H.,Ishikawa J.,Hanamoto A.,Takahashi C.,Shinose M.,Takahashi Y.,Horikawa H.,Nakazawa H.,Osonoe T.,Kikuchi H.,Shiba T.,Sakaki Y.,Hattori M.
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.
Proc. Natl. Acad. Sci. U.S.A.
98
12215-12220
2001
532604
Ikeda H.,Ishikawa J.,Hanamoto A.,Shinose M.,Kikuchi H.,Shiba T.,Sakaki Y.,Hattori M.,Omura S.
Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.
Nat. Biotechnol.
21
526-531
2003
532605
Seo M.J.,Zhu D.,Endo S.,Ikeda H.,Cane D.E.
Genome mining in Streptomyces. Elucidation of the role of Baeyer-Villiger monooxygenases and non-heme iron-dependent dehydrogenase/oxygenases in the final steps of the biosynthesis of pentalenolactone and neopentalenolactone.
Biochemistry
50
1739-1754
2011
532606
Takamatsu S.,Xu L.H.,Fushinobu S.,Shoun H.,Komatsu M.,Cane D.E.,Ikeda H.
Pentalenic acid is a shunt metabolite in the biosynthesis of the pentalenolactone family of metabolites: hydroxylation of 1-deoxypentalenic acid mediated by CYP105D7 (SAV_7469) of Streptomyces avermitilis.
J. Antibiot.
64
65-71
2011
