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Sequence of ILV3_YEAST

EC Number:4.2.1.9

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
4.2.1.9
dihydroxy-acid dehydratase
P39522
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
585
62861
Swiss-Prot
Reaction
2,3-dihydroxy-3-methylbutanoate = 3-methyl-2-oxobutanoate + H2O
Other sequences found for EC No. 4.2.1.9

General information:

Sequence
show sequence in fasta format
  0 MGLLTKVATS RQFSTTRCVA KKLNKYSYII TEPKGQGASQ AMLYATGFKK EDFKKPQVGV
 60 GSCWWSGNPC NMHLLDLNNR CSQSIEKAGL KAMQFNTIGV SDGISMGTKG MRYSLQSREI
120 IADSFETIMM AQHYDANIAI PSCDKNMPGV MMAMGRHNRP SIMVYGGTIL PGHPTCGSSK
180 ISKNIDIVSA FQSYGEYISK QFTEEEREDV VEHACPGPGS CGGMYTANTM ASAAEVLGLT
240 IPNSSSFPAV SKEKLAECDN IGEYIKKTME LGILPRDILT KEAFENAITY VVATGGSTNA
300 VLHLVAVAHS AGVKLSPDDF QRISDTTPLI GDFKPSGKYV MADLINVGGT QSVIKYLYEN
360 NMLHGNTMTV TGDTLAERAK KAPSLPEGQE IIKPLSHPIK ANGHLQILYG SLAPGGAVGK
420 ITGKEGTYFK GRARVFEEEG AFIEALERGE IKKGEKTVVV IRYEGPRGAP GMPEMLKPSS
480 ALMGYGLGKD VALLTDGRFS GGSHGFLIGH IVPEAAEGGP IGLVRDGDEI IIDADNNKID
540 LLVSDKEMAQ RKQSWVAPPP RYTRGTLSKY AKLVSNASNG CVLDA
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
47469
Galibert F.,Alexandraki D.,Baur A.,Boles E.,Chalwatzis N.,Chuat J.-C.,Coster F.,Cziepluch C.,de Haan M.,Domdey H.,Durand P.,Entian K.-D.,Gatius M.,Goffeau A.,Grivell L.A.,Hennemann A.,Herbert C.J.,Heumann K.,Hilger F.,Hollenberg C.P.,Huang M.-E.,Jacq C.,Jauniaux J.-C.,Katsoulou C.,Kirchrath L.,Kleine K.,Kordes E.,Koetter P.,Liebl S.,Louis E.J.,Manus V.,Mewes H.-W.,Miosga T.,Obermaier B.,Perea J.,Pohl T.M.,Portetelle D.,Pujol A.,Purnelle B.,Ramezani Rad M.,Rasmussen S.W.,Rose M.,Rossau R.,Schaaff-Gerstenschlaeger I.,Smits P.H.M.,Scarcez T.,Soriano N.,To Van D.,Tzermia M.,Van Broekhoven A.,Vandenbol M.,Wedler H.,von Wettstein D.,Wambutt R.,Zagulski M.,Zollner A.,Karpfinger-Hartl L.
Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X.
EMBO J.
15
2031-2049
1996
8641269
47470
Engel S.R.,Dietrich F.S.,Fisk D.G.,Binkley G.,Balakrishnan R.,Costanzo M.C.,Dwight S.S.,Hitz B.C.,Karra K.,Nash R.S.,Weng S.,Wong E.D.,Lloyd P.,Skrzypek M.S.,Miyasato S.R.,Simison M.,Cherry J.M.
The reference genome sequence of Saccharomyces cerevisiae: Then and now.
G3 (Bethesda)
4
389-398
2014
24374639
47471
Velasco J.A.,Cansado J.,Pena M.C.,Kawakami T.,Laborda J.,Notario V.
Cloning of the dihydroxyacid dehydratase-encoding gene (ILV3) from Saccharomyces cerevisiae.
Gene
137
179-185
1993
8299945
47472
Ghaemmaghami S.,Huh W.-K.,Bower K.,Howson R.W.,Belle A.,Dephoure N.,O'Shea E.K.,Weissman J.S.
Global analysis of protein expression in yeast.
Nature
425
737-741
2003
14562106
47473
Schoondermark-Stolk S.A.,Jansen M.,Veurink J.H.,Verkleij A.J.,Verrips C.T.,Euverink G.J.,Boonstra J.,Dijkhuizen L.
Rapid identification of target genes for 3-methyl-1-butanol production in Saccharomyces cerevisiae.
Appl. Microbiol. Biotechnol.
70
237-246
2006
16041576
47474
Ihrig J.,Hausmann A.,Hain A.,Richter N.,Hamza I.,Lill R.,Muehlenhoff U.
Iron regulation through the back door: iron-dependent metabolite levels contribute to transcriptional adaptation to iron deprivation in Saccharomyces cerevisiae.
Eukaryot. Cell
9
460-471
2010
20008079
47475
Chen X.,Nielsen K.F.,Borodina I.,Kielland-Brandt M.C.,Karhumaa K.
Increased isobutanol production in Saccharomyces cerevisiae by overexpression of genes in valine metabolism.
Biotechnol. Biofuels
4
21-21
2011
21798060
47476
Muehlenhoff U.,Richter N.,Pines O.,Pierik A.J.,Lill R.
Specialized function of yeast Isa1 and Isa2 proteins in the maturation of mitochondrial [4Fe-4S] proteins.
J. Biol. Chem.
286
41205-41216
2011
21987576
47477
Brat D.,Weber C.,Lorenzen W.,Bode H.B.,Boles E.
Cytosolic re-localization and optimization of valine synthesis and catabolism enables inseased isobutanol production with the yeast Saccharomyces cerevisiae.
Biotechnol. Biofuels
5
65-65
2012
22954227
47478
Park S.H.,Kim S.,Hahn J.S.
Metabolic engineering of Saccharomyces cerevisiae for the production of isobutanol and 3-methyl-1-butanol.
Appl. Microbiol. Biotechnol.
98
9139-9147
2014
25280745
47479
Teo W.S.,Ling H.,Yu A.Q.,Chang M.W.
Metabolic engineering of Saccharomyces cerevisiae for production of fatty acid short- and branched-chain alkyl esters biodiesel.
Biotechnol. Biofuels
8
177-177
2015
26543501
47480
Melber A.,Na U.,Vashisht A.,Weiler B.D.,Lill R.,Wohlschlegel J.A.,Winge D.R.
Role of Nfu1 and Bol3 in iron-sulfur cluster transfer to mitochondrial clients.
Elife
5
0-0
2016
27532773
47481
Generoso W.C.,Brinek M.,Dietz H.,Oreb M.,Boles E.
Secretion of 2,3-dihydroxyisovalerate as a limiting factor for isobutanol production in Saccharomyces cerevisiae.
FEMS Yeast Res.
17
0-0
2017
28505306
47482
Wess J.,Brinek M.,Boles E.
Improving isobutanol production with the yeast Saccharomyces cerevisiae by successively blocking competing metabolic pathways as well as ethanol and glycerol formation.
Biotechnol. Biofuels
12
173-173
2019
31303893
47483
Park S.H.,Hahn J.S.
Development of an efficient cytosolic isobutanol production pathway in Saccharomyces cerevisiae by optimizing copy numbers and expression of the pathway genes based on the toxic effect of alpha-acetolactate.
Sci. Rep.
9
3996-3996
2019
30850698
47484
Su Y.,Shao W.,Zhang A.,Zhang W.
Improving isobutanol tolerance and titers through EMS mutagenesis in Saccharomyces cerevisiae.
FEMS Yeast Res.
21
0-0
2021
33620449