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Sequence of HXK1_CANAL

EC Number:2.7.1.1

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
hexokinase
Q59RW5
Candida albicans (strain SC5314 / ATCC MYA-2876)
493
54823
Reaction
ATP + D-glucose = ADP + D-glucose 6-phosphate
Other sequences found for EC No. 2.7.1.1

General information:

Sequence
show sequence in fasta format
  0 MTETSISGLR GPKSMYFMEI VDVSSQESSV LSSIVESFTS AVSASNLGVY SDEVLCDIKS
 60 SLKENSPITM LPNYNVSPTG DEHGQYLVID LGGSTLRIAV VDISKPHPNL SRSERITIVV
120 EKSWIIGNDF KRIDGEFFKY IGSKINEILM GQNVIDVKSV INTGITWSFP LETTDYNRGK
180 IKHVSKGYTV GEDIYDKDLK MVLEDTLRQE YGLTLDVQSI LNDSLAVYSA GCFIDSKMKL
240 AMVLGTGINM CCSLKRSSDI HPSKMLADAT LFNCELSLFG QNLCKDFATK YDIIIDKRFA
300 GLSHHFKTFM EPDPITKTLF QPHELMTSGR YLPELTRLVV VDLIEAGEIF QNVDHQQMYQ
360 EYGGFSGELI CFVHENDDYD DIHDKLCKAY GWTTVGLSDI VCLKEVVSCI IKRAAFIVAN
420 AIIAFFKLLG SDELGGDVTI GYVGSVLNYF HKYRRLIVEY VNSAEEAKGI KVDLKLIENS
480 SIIGAAIGAA YHK
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
45691
Jones T.,Federspiel N.A.,Chibana H.,Dungan J.,Kalman S.,Magee B.B.,Newport G.,Thorstenson Y.R.,Agabian N.,Magee P.T.,Davis R.W.,Scherer S.
The diploid genome sequence of Candida albicans.
Proc. Natl. Acad. Sci. U.S.A.
101
7329-7334
2004
45692
van het Hoog M.,Rast T.J.,Martchenko M.,Grindle S.,Dignard D.,Hogues H.,Cuomo C.,Berriman M.,Scherer S.,Magee B.B.,Whiteway M.,Chibana H.,Nantel A.,Magee P.T.
Assembly of the Candida albicans genome into sixteen supercontigs aligned on the eight chromosomes.
Genome Biol.
8
0-0
2007
45693
Muzzey D.,Schwartz K.,Weissman J.S.,Sherlock G.
Assembly of a phased diploid Candida albicans genome facilitates allele-specific measurements and provides a simple model for repeat and indel structure.
Genome Biol.
14
0-0
2013
45694
Kumar M.J.,Jamaluddin M.S.,Natarajan K.,Kaur D.,Datta A.
The inducible N-acetylglucosamine catabolic pathway gene cluster in Candida albicans: discrete N-acetylglucosamine-inducible factors interact at the promoter of NAG1.
Proc. Natl. Acad. Sci. U.S.A.
97
14218-14223
2000
45695
Yamada-Okabe T.,Sakamori Y.,Mio T.,Yamada-Okabe H.
Identification and characterization of the genes for N-acetylglucosamine kinase and N-acetylglucosamine-phosphate deacetylase in the pathogenic fungus Candida albicans.
Eur. J. Biochem.
268
2498-2505
2001
45696
Singh P.,Ghosh S.,Datta A.
Attenuation of virulence and changes in morphology in Candida albicans by disruption of the N-acetylglucosamine catabolic pathway.
Infect. Immun.
69
7898-7903
2001
45697
Wendland J.,Hellwig D.,Walther A.,Sickinger S.,Shadkchan Y.,Martin R.,Bauer J.,Osherov N.,Tretiakov A.,Saluz H.P.
Use of the porcine intestinal epithelium (PIE)-assay to analyze early stages of colonization by the human fungal pathogen Candida albicans.
J. Basic Microbiol.
46
513-523
2006
45698
Bennett R.J.,Johnson A.D.
The role of nutrient regulation and the Gpa2 protein in the mating pheromone response of C. albicans.
Mol. Microbiol.
62
100-119
2006
45699
Wendland J.,Schaub Y.,Walther A.
N-acetylglucosamine utilization by Saccharomyces cerevisiae based on expression of Candida albicans NAG genes.
Appl. Environ. Microbiol.
75
5840-5845
2009
45700
Gunasekera A.,Alvarez F.J.,Douglas L.M.,Wang H.X.,Rosebrock A.P.,Konopka J.B.
Identification of GIG1, a GlcNAc-induced gene in Candida albicans needed for normal sensitivity to the chitin synthase inhibitor nikkomycin Z.
Eukaryot. Cell
9
1476-1483
2010
45701
Naseem S.,Gunasekera A.,Araya E.,Konopka J.B.
N-acetylglucosamine (GlcNAc) induction of hyphal morphogenesis and transcriptional responses in Candida albicans are not dependent on its metabolism.
J. Biol. Chem.
286
28671-28680
2011
45702
Rao K.H.,Ghosh S.,Natarajan K.,Datta A.
N-acetylglucosamine kinase, HXK1 is involved in morphogenetic transition and metabolic gene expression in Candida albicans.
PLoS ONE
8
0-0
2013
45703
Rao K.H.,Ruhela D.,Ghosh S.,Abdin M.Z.,Datta A.
N-acetylglucosamine kinase, HXK1 contributes to white-opaque morphological transition in Candida albicans.
Biochem. Biophys. Res. Commun.
445
138-144
2014