Sequence of PRMC_THEMA

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
peptide chain release factor N5-glutamine methyltransferase
Q9WYV8
Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
282
31609
Reaction
S-adenosyl-L-methionine + [peptide chain release factor 1 or 2]-L-glutamine = S-adenosyl-L-homocysteine + [peptide chain release factor 1 or 2]-N5-methyl-L-glutamine
Sequences with same EC No.
Sequence
show sequence in fasta format
  0 MDTRKNVSGA ERKIWSLIRD CSGKLEGVTE TSVLEVLLIV SRVLGIRKED LFLKDLGVSP
 60 TEEKRILELV EKRASGYPLH YILGEKEFMG LSFLVEEGVF VPRPETEELV ELALELIRKY
120 GIKTVADIGT GSGAIGVSVA KFSDAIVFAT DVSSKAVEIA RKNAERHGVS DRFFVRKGEF
180 LEPFKEKFAS IEMILSNPPY VKSSAHLPKD VLFEPPEALF GGEDGLDFYR EFFGRYDTSG
240 KIVLMEIGED QVEELKKIVS DTVFLKDSAG KYRFLLLNRR SS
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
193182
Nelson K.E.,Clayton R.A.,Gill S.R.,Gwinn M.L.,Dodson R.J.,Haft D.H.,Hickey E.K.,Peterson J.D.,Nelson W.C.,Ketchum K.A.,McDonald L.A.,Utterback T.R.,Malek J.A.,Linher K.D.,Garrett M.M.,Stewart A.M.,Cotton M.D.,Pratt M.S.,Phillips C.A.,Richardson D.L.,Heidelberg J.F.,Sutton G.G.,Fleischmann R.D.,Eisen J.A.,White O.,Salzberg S.L.,Smith H.O.,Venter J.C.,Fraser C.M.
Evidence for lateral gene transfer between Archaea and Bacteria from genome sequence of Thermotoga maritima.
Nature
399
323-329
1999
193183
Yoon H.J.,Kang K.Y.,Ahn H.J.,Shim S.M.,Ha J.Y.,Lee S.K.,Mikami B.,Suh S.W.
X-ray crystallographic studies of HemK from Thermotoga maritima, an N5-glutamine methyltransferase.
Mol. Cells
16
266-269
2003
193184
Schubert H.L.,Phillips J.D.,Hill C.P.
Structures along the catalytic pathway of PrmC/HemK, an N5-glutamine AdoMet-dependent methyltransferase.
Biochemistry
42
5592-5599
2003
193185
Agarwal R.,Burley S.K.,Swaminathan S.
A novel mode of dimerization via formation of a glutamate anhydride crosslink in a protein crystal structure.
Proteins
71
1038-1041
2008