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Sequence of NSR_PYRFU

EC Number:1.8.1.14

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
CoA-disulfide reductase
Q8U1M0
Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)
442
48720
Reaction
2 CoA + NADP+ = CoA-disulfide + NADPH + H+
Other sequences found for EC No. 1.8.1.14

EC Number:1.8.1.18

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
NAD(P)H sulfur oxidoreductase (CoA-dependent)
Q8U1M0
Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)
442
48720
Reaction
hydrogen sulfide + NAD(P)+ = sulfur + NAD(P)H + H+
Other sequences found for EC No. 1.8.1.18

General information:

Sequence
show sequence in fasta format
  0 MEKKKVVIIG GGAAGMSAAS RVKRLRPEWD VKVFEATEWV SHAPCGIPYV VEGIAPKEKL
 60 MHYPPEVFIK KRGIDLHLKA EVIEVETGYV RVRENGEEKS YEWDYLVFAN GASPQIPEIE
120 GVDLPGVFTA DLPPDAVAIT EYMEKNKVED VVIIGTGYIA LEMAEAFVTR GKNVTLIGRS
180 ERVLRKTFDK EITDIVEEKL RQHLNLRLHE KTLSIEGRER VEKVITDGGE YKADLVIIAT
240 GIKPNVELAK QLGVKIGETG AIWTNEKMQT SVENVYAAGD VAETKHVITG KRVWIPLAPA
300 GNKMGYVAGS NIAGKEIEFP GVLGTSITKF MDLEIGKTGL TENEAVKEGY DVRTAFIKAN
360 TKPHYYPGGR EIWLKGVVDN ETNRLLGVQA VGAEILPRID SAAAMITAGF TTKDVFFTDL
420 AYAPPFAPVW DPLIVLARVL KF
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
326896
Maeder D.L.,Weiss R.B.,Dunn D.M.,Cherry J.L.,Gonzalez J.M.,DiRuggiero J.,Robb F.T.
Divergence of the hyperthermophilic archaea Pyrococcus furiosus and P. horikoshii inferred from complete genomic sequences.
Genetics
152
1299-1305
1999
326897
Harris D.R.,Ward D.E.,Feasel J.M.,Lancaster K.M.,Murphy R.D.,Mallet T.C.,Crane E.J. III
Discovery and characterization of a coenzyme A disulfide reductase from Pyrococcus horikoshii. Implications for this disulfide metabolism of anaerobic hyperthermophiles.
FEBS J.
272
1189-1200
2005
326898
Schut G.J.,Bridger S.L.,Adams M.W.
Insights into the metabolism of elemental sulfur by the hyperthermophilic archaeon Pyrococcus furiosus: characterization of a coenzyme A-dependent NAD(P)H sulfur oxidoreductase.
J. Bacteriol.
189
4431-4441
2007
326899
Bridger S.L.,Clarkson S.M.,Stirrett K.,DeBarry M.B.,Lipscomb G.L.,Schut G.J.,Westpheling J.,Scott R.A.,Adams M.W.
Deletion strains reveal metabolic roles for key elemental sulfur-responsive proteins in Pyrococcus furiosus.
J. Bacteriol.
193
6498-6504
2011
326900
Harnvoravongchai P.,Kobori H.,Orita I.,Nakamura S.,Imanaka T.,Fukui T.
Characterization and gene deletion analysis of four homologues of group 3 pyridine nucleotide disulfide oxidoreductases from Thermococcus kodakarensis.
Extremophiles
18
603-616
2014