Sequence of SCOT1_PIG

EC Number:2.8.3.5

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
3-oxoacid CoA-transferase
Q29551
Sus scrofa
520
56338
Reaction
succinyl-CoA + a 3-oxo acid = succinate + a 3-oxoacyl-CoA
Other sequences found for EC No. 2.8.3.5

General information:

Sequence
show sequence in fasta format
  0 MAALTLLSSR LRLCASAYRS GGAWSQGCAG YFSTSTRRHT KFYTDAVEAV KDIPNGATVL
 60 VGGFGLCGIP ENLIGALLKT GVKELTAVSN NAGVDNFGLG LLLQSKQIKR MISSYVGENA
120 EFERQYLAGE LEVELTPQGT LAERIRAGGA GVPAFYTSTG YGTLVQEGGS PIKYNKDGSI
180 AIASKPREVR EFNGQHFILE EAIRGDFALV KAWKADQAGN VTFRKSARNF NLPMCKAAET
240 TVVEVEEIVD IGSFAPEDIH IPKIYVHRLV KGEKYEKRIE RLSVRKEEDV KTRSGKLGDN
300 VRERIIKRAA LEFEDGMYAN LGIGIPLLAS NFISPNMTVH LQSENGILGL GPYPLQNEVD
360 ADLINAGKET VTVLPGASYF SSDESFAMIR GGHVNLTMLG AMQVSKYGDL ANWMIPGKLV
420 KGMGGAMDLV SSAKTKVVVT MEHSAKGNAH KIMEKCTLPL TGKQCVNRII TEKAVFDVDS
480 KKGLTLIELW EGLTVDDIKK STGCDFAVSP KLIPMQQVTT
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
95910
Lin T.,Bridger W.A.
Sequence of a cDNA clone encoding pig heart mitochondrial CoA transferase.
J. Biol. Chem.
267
975-978
1992
95912
Rochet J.C.,Bridger W.A.
Identification of glutamate 344 as the catalytic residue in the active site of pig heart CoA transferase.
Protein Sci.
3
975-981
1994
95913
Bateman K.S.,Brownie E.R.,Wolodko W.T.,Fraser M.E.
Structure of the mammalian CoA transferase from pig heart.
Biochemistry
41
14455-14462
2002
95915
Coros A.M.,Swenson L.,Wolodko W.T.,Fraser M.E.
Structure of the CoA transferase from pig heart to 1.7 A resolution.
Acta Crystallogr. D
60
1717-1725
2004
95916
Tammam S.D.,Rochet J.C.,Fraser M.E.
Identification of the cysteine residue exposed by the conformational change in pig heart succinyl-CoA:3-ketoacid coenzyme A transferase on binding coenzyme A.
Biochemistry
46
10852-10863
2007
95917
Coker S.F.,Lloyd A.J.,Mitchell E.,Lewis G.R.,Coker A.R.,Shoolingin-Jordan P.M.
The high-resolution structure of pig heart succinyl-CoA:3-oxoacid coenzyme A transferase.
Acta Crystallogr. D
66
797-805
2010
95918
Fraser M.E.,Hayakawa K.,Brown W.D.
Catalytic role of the conformational change in succinyl-CoA:3-oxoacid CoA transferase on binding CoA.
Biochemistry
49
10319-10328
2010