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Sequence of HOSM_YEAST

EC Number:2.3.3.14

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
homocitrate synthase
Q12122
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
440
48594
Reaction
acetyl-CoA + H2O + 2-oxoglutarate = (2R)-2-hydroxybutane-1,2,4-tricarboxylate + CoA

General information:

Sequence
show sequence in fasta format
  0 MSENNEFQSV TESTTAPTTS NPYGPNPADY LSNVKNFQLI DSTLREGEQF ANAFFDTEKK
 60 IEIARALDDF GVDYIELTSP VASEQSRKDC EAICKLGLKA KILTHIRCHM DDARVAVETG
120 VDGVDVVIGT SKFLRQYSHG KDMNYIAKSA VEVIEFVKSK GIEIRFSSED SFRSDLVDLL
180 NIYKTVDKIG VNRVGIADTV GCANPRQVYE LIRTLKSVVS CDIECHFHND TGCAIANAYT
240 ALEGGARLID VSVLGIGERN GITPLGGLMA RMIVAAPDYV RSKYKLHKIR DIENLVADAV
300 EVNIPFNNPI TGFCAFTHKA GIHAKAILAN PSTYEILDPH DFGMKRYIHF ANRLTGWNAI
360 KSRVDQLNLN LTDDQIKEVT AKIKKLGDVR PLNIDDVDSI IKDFHAELST PLLKPVNKGT
420 DDDNIDISNG HVSKKAKVTK
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
303563
Woelfl S.,Haneman V.,Saluz H.P.
Analysis of a 26,756 bp segment from the left arm of yeast chromosome IV.
Yeast
12
1549-1554
1996
303564
Jacq C.,Alt-Moerbe J.,Andre B.,Arnold W.,Bahr A.,Ballesta J.P.G.,Bargues M.,Baron L.,Becker A.,Biteau N.,Bloecker H.,Blugeon C.,Boskovic J.,Brandt P.,Brueckner M.,Buitrago M.J.,Coster F.,Delaveau T.,del Rey F.,Dujon B.,Eide L.G.,Garcia-Cantalejo J.M.,Goffeau A.,Gomez-Peris A.,Granotier C.,Hanemann V.,Hankeln T.,Hoheisel J.D.,Jaeger W.,Jimenez A.,Jonniaux J.-L.,Kraemer C.,Kuester H.,Laamanen P.,Legros Y.,Louis E.J.,Moeller-Rieker S.,Monnet A.,Moro M.,Mueller-Auer S.,Nussbaumer B.,Paricio N.,Paulin L.,Perea J.,Perez-Alonso M.,Perez-Ortin J.E.,Pohl T.M.,Prydz H.,Purnelle B.,Rasmussen S.W.,Remacha M.A.,Revuelta J.L.,Rieger M.,Salom D.,Saluz H.P.,Saiz J.E.,Saren A.-M.,Schaefer M.,Scharfe M.,Schmidt E.R.,Schneider C.,Scholler P.,Schwarz S.,Soler-Mira A.,Urrestarazu L.A.,Verhasselt P.,Vissers S.,Voet M.,Volckaert G.,Wagner G.,Wambutt R.,Wedler E.,Wedler H.,Woelfl S.,Harris D.E.,Bowman S.,Brown D.,Churcher C.M.,Connor R.,Dedman K.,Gentles S.,Hamlin N.,Hunt S.,Jones L.,McDonald S.,Murphy L.D.,Niblett D.,Odell C.,Oliver K.,Rajandream M.A.,Richards C.,Shore L.,Walsh S.V.,Barrell B.G.,Dietrich F.S.,Mulligan J.T.,Allen E.,Araujo R.,Aviles E.,Berno A.,Carpenter J.,Chen E.,Cherry J.M.,Chung E.,Duncan M.,Hunicke-Smith S.,Hyman R.W.,Komp C.,Lashkari D.,Lew H.,Lin D.,Mosedale D.,Nakahara K.,Namath A.,Oefner P.,Oh C.,Petel F.X.,Roberts D.,Schramm S.,Schroeder M.,Shogren T.,Shroff N.,Winant A.,Yelton M.A.,Botstein D.,Davis R.W.,Johnston M.,Andrews S.,Brinkman R.,Cooper J.,Ding H.,Du Z.,Favello A.,Fulton L.,Gattung S.,Greco T.,Hallsworth K.,Hawkins J.,Hillier L.W.,Jier M.,Johnson D.,Johnston L.,Kirsten J.,Kucaba T.,Langston Y.,Latreille P.,Le T.,Mardis E.,Menezes S.,Miller N.,Nhan M.,Pauley A.,Peluso D.,Rifkin L.,Riles L.,Taich A.,Trevaskis E.,Vignati D.,Wilcox L.,Wohldman P.,Vaudin M.,Wilson R.,Waterston R.,Albermann K.,Hani J.,Heumann K.,Kleine K.,Mewes H.-W.,Zollner A.,Zaccaria P.
The nucleotide sequence of Saccharomyces cerevisiae chromosome IV.
Nature
387
75-78
1997
303565
Engel S.R.,Dietrich F.S.,Fisk D.G.,Binkley G.,Balakrishnan R.,Costanzo M.C.,Dwight S.S.,Hitz B.C.,Karra K.,Nash R.S.,Weng S.,Wong E.D.,Lloyd P.,Skrzypek M.S.,Miyasato S.R.,Simison M.,Cherry J.M.
The reference genome sequence of Saccharomyces cerevisiae: Then and now.
G3 (Bethesda)
4
389-398
2014
303566
Hu Y.,Rolfs A.,Bhullar B.,Murthy T.V.S.,Zhu C.,Berger M.F.,Camargo A.A.,Kelley F.,McCarron S.,Jepson D.,Richardson A.,Raphael J.,Moreira D.,Taycher E.,Zuo D.,Mohr S.,Kane M.F.,Williamson J.,Simpson A.J.G.,Bulyk M.L.,Harlow E.,Marsischky G.,Kolodner R.D.,LaBaer J.
Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae.
Genome Res.
17
536-543
2007
303567
Ghaemmaghami S.,Huh W.-K.,Bower K.,Howson R.W.,Belle A.,Dephoure N.,O'Shea E.K.,Weissman J.S.
Global analysis of protein expression in yeast.
Nature
425
737-741
2003
303568
Li X.,Gerber S.A.,Rudner A.D.,Beausoleil S.A.,Haas W.,Villen J.,Elias J.E.,Gygi S.P.
Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae.
J. Proteome Res.
6
1190-1197
2007
303569
Chi A.,Huttenhower C.,Geer L.Y.,Coon J.J.,Syka J.E.P.,Bai D.L.,Shabanowitz J.,Burke D.J.,Troyanskaya O.G.,Hunt D.F.
Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry.
Proc. Natl. Acad. Sci. U.S.A.
104
2193-2198
2007
303570
Albuquerque C.P.,Smolka M.B.,Payne S.H.,Bafna V.,Eng J.,Zhou H.
A multidimensional chromatography technology for in-depth phosphoproteome analysis.
Mol. Cell. Proteomics
7
1389-1396
2008
303571
Holt L.J.,Tuch B.B.,Villen J.,Johnson A.D.,Gygi S.P.,Morgan D.O.
Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.
Science
325
1682-1686
2009