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Sequence of HGDB_ACIFV

EC Number:4.2.1.167

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
(R)-2-hydroxyglutaryl-CoA dehydratase
P11570
Acidaminococcus fermentans (strain ATCC 25085 / DSM 20731 / CCUG 9996 / CIP 106432 / VR4)
379
42028
Reaction
(R)-2-hydroxyglutaryl-CoA = (E)-glutaconyl-CoA + H2O
Other sequences found for EC No. 4.2.1.167

General information:

Sequence
  0 MAISALIEEF QKVSASPKTM LAKYKAQGKK AIGCLPYYVP EELVYAAGMV PMGVWGCNGK
 60 QEVRSKEYCA SFYCTIAQQS LEMLLDGTLD GLDGIITPVL CDTLRPMSQN FKVAMKDKMP
120 VIFLAHPQVR QNAAGKQFTY DAYSEVKGHL EEICGHEITN DAILDAIKVY NKSRAARREF
180 CKLANEHPDL IPASVRATVL RAAYFMLKDE YTEKLEELNK ELAAAPAGKF DGHKVVVSGI
240 IYNMPGILKA MDDNKLAIAA DDCAYESRSF AVDAPEDLDN GLQALAVQFS KQKNDVLLYD
300 PEFAKNTRSE HVCNLVKESG AEGLIVFMMQ FCDPEEMEYP DLKKALDAHH IPHVKIGVDQ
360 MTRDFGQAQT ALEAFAESL
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
808545
Dutscho R.,Wohlfarth G.,Buckel P.,Buckel W.
Cloning and sequencing of the genes of 2-hydoxyglutaryl-CoA dehydratase from Acidaminococcus fermentans.
Eur. J. Biochem.
181
741-746
1989
808546
Chang Y.J.,Pukall R.,Saunders E.,Lapidus A.,Copeland A.,Nolan M.,Glavina Del Rio T.,Lucas S.,Chen F.,Tice H.,Cheng J.F.,Han C.,Detter J.C.,Bruce D.,Goodwin L.,Pitluck S.,Mikhailova N.,Liolios K.,Pati A.,Ivanova N.,Mavromatis K.,Chen A.,Palaniappan K.,Land M.,Hauser L.,Jeffries C.D.,Brettin T.,Rohde M.,Goker M.,Bristow J.,Eisen J.A.,Markowitz V.,Hugenholtz P.,Kyrpides N.C.,Klenk H.P.
Complete genome sequence of Acidaminococcus fermentans type strain (VR4).
Stand. Genomic Sci.
3
1-14
2010
808547
Schweiger G.,Dutscho R.,Buckel W.
Purification of 2-hydroxyglutaryl-CoA dehydratase from Acidaminococcus fermentans. An iron-sulfur protein.
Eur. J. Biochem.
169
441-448
1987
808548
Buckel W.
The reversible dehydration of (R)-2-hydroxyglutarate to (E)-glutaconate.
Eur. J. Biochem.
106
439-447
1980
808549
Mueller U.,Buckel W.
Activation of (R)-2-hydroxyglutaryl-CoA dehydratase from Acidaminococcus fermentans.
Eur. J. Biochem.
230
698-704
1995
808550
Hans M.,Buckel W.,Bill E.
The iron-sulfur clusters in 2-hydroxyglutaryl-CoA dehydratase from Acidaminococcus fermentans. Biochemical and spectroscopic investigations.
Eur. J. Biochem.
267
7082-7093
2000