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Sequence of C4M7X2_ENTHI

EC Number:6.1.1.6

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
lysine-tRNA ligase
C4M7X2
Entamoeba histolytica
769
86534
Reaction
ATP + L-lysine + tRNALys = AMP + diphosphate + L-lysyl-tRNALys

General information:

Sequence
show sequence in fasta format
  0 MSKQLFLNRC KDVEEYQKAG HNPWPHKFNV SITVPEFIAK YSGLEKSQVS DDIVSVAGRV
 60 LSKRSSSSAL MFIDLHDSQT KLQIMLNKSA YENKEDFVSL TKMIYRGDIC GFTGHPTRTK
120 TGELSLIPIS GMILSPCLHM LPSMHYGLGD QETRFRKRYL DLIVNPESVK NFVLRTKVVK
180 AVRKYLDDKG FLEVETPILN TIPGGATARP FITHHNQLDI QMYMRIAPEL YLKELVVGGI
240 NRVYEIGRLF RNEGIDQTHN PEFTTCEFYM AYADYNDIMK MTEELLGNMV KDITGGSTKL
300 EIKDRLMDIN NEEDIKMLEK FFKEPIPRPF NSAECSKVIE KHCTELNYYY DGNNEKAMKK
360 LFADFVTEKK MVLDFTAPFK RISYVHALEE KFGEKIPRPL DGPEALTFLK KQAIRFNAIC
420 AEPQTTARVM DKLFGDLIEV DLVQPTFVCD QPQLMSPLAK YHRSEPELTE RFELFILKRE
480 IANAYTELNN PIVQRSNFEQ QAKDKAAGDD EAQLVDEVFL DAIEHAFPPT GGWGLGIDRL
540 AMLLADVDNI KEVILFPTMR PEDELEKKAR EAKEDAMVAQ ELAATEEKGG KKVVKPKANK
600 QQPVKEVLDG FQLEIRVGKI VEAGPHPNSE HLLALKVDVG EEKPRSVVAG LAEHYKPEEL
660 LNQKATFVCN LKPSKLRGVA SEAMILAATS LDGTKVKFCH PSADAAIGAQ VIPKEGKVTI
720 SAKKISIDVV GKMNLALKGG LVRTNDVPLI VKDTELTVTV DEVVDGTVR
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
38280461
Loftus B.J.,Anderson I.,Davies R.,Alsmark U.C.,Samuelson J.,Amedeo P.,Roncaglia P.,Berriman M.,Hirt R.P.,Mann B.J.,Nozaki T.,Suh B.,Pop M.,Duchene M.,Ackers J.,Tannich E.,Leippe M.,Hofer M.,Bruchhaus I.,Willhoeft U.,Bhattacharya A.,Chillingworth T.,Churcher C.M.,Hance Z.,Harris B.,Harris D.,Jagels K.,Moule S.,Mungall K.L.,Ormond D.,Squares R.,Whitehead S.,Quail M.A.,Rabbinowitsch E.,Norbertczak H.,Price C.,Wang Z.,Guillen N.,Gilchrist C.,Stroup S.E.,Bhattacharya S.,Lohia A.,Foster P.G.,Sicheritz-Ponten T.,Weber C.,Singh U.,Mukherjee C.,El-Sayed N.M.A.,Petri W.A.,Clark C.G.,Embley T.M.,Barrell B.G.,Fraser C.M.,Hall N.
The genome of the protist parasite Entamoeba histolytica.
Nature
433
865-868
2005
38280463
Bonnefond L.,Castro de Moura M.,Ribas de Pouplana L.,Nureki O.
Crystal structures of Entamoeba histolytica lysyl-tRNA synthetase reveal conformational changes upon lysine binding and a specific helix bundle domain.
FEBS Lett.
588
4478-4486
2014