EC Number   |
Protein Variants |
Reference |
|---|
    7.1.2.1 | A135F |
rate of acidification rapidly declines |
246942 |
| 7.1.2.1 | A135G |
wild-type rate of medium acidification |
246942 |
| 7.1.2.1 | A135I |
reduction in initial rate of acidification |
246942 |
| 7.1.2.1 | A135L |
wild-type rate of medium acidification |
246942 |
| 7.1.2.1 | A135V |
wild-type rate of medium acidification |
246942 |
| 7.1.2.1 | C376L |
mutation decreases activity and phosphorylation to a similar extent, ATPase activity is 65% of the activity of the wild type enzyme, 5fold increase in Ki for vanadate |
246933 |
| 7.1.2.1 | D226N |
5% decrease in ATPase activity, 35% decrease in H+ transport |
246933 |
| 7.1.2.1 | D226N |
decreased turnover and level of phosphorylated enzyme-intermediate |
246933 |
| 7.1.2.1 | D378E |
5fold lower Ki for vanadate than in wild type |
246933 |
| 7.1.2.1 | D378E |
no decrease in ATPase activity, 65% decrease in H+ transport |
246933 |
