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EC Number
Protein Variants
Commentary
Reference
6.5.1.8
C100A
inactive for ligation reaction
-
,
741323
6.5.1.8
C122A
the mutant does not bind Mn2+
749256
6.5.1.8
C78A
almost complete loss of activity
740694
6.5.1.8
C78A
completely inactive
748103
6.5.1.8
C78S
complete loss of activity
740694
6.5.1.8
C98A
mutation in predicted metal-binding site, loss of activity
740053
6.5.1.8
D75A
almost complete loss of activity
740694
6.5.1.8
D75A
the mutation allows cyclic phosphodiester hydrolysis but cripples 3'-phosphate guanylylation
748103
6.5.1.8
D75E
complete loss of activity
740694
6.5.1.8
D75N
complete loss of activity
740694
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