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Protein Variants:
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EC Number
Protein Variants
Commentary
Reference
5.1.3.37
D152G
mutation eliminates almost all of both the lyase and epimerase activities
652156
5.1.3.37
D173E
54% residual activity
734159
5.1.3.37
D178E
complete loss of activity
734159
5.1.3.37
D178N
complete loss of activity
734159
5.1.3.37
D317A
about 5% of wild-type activity
734293
5.1.3.37
D320A
complete loss of activity
-
,
734293
5.1.3.37
D368N
about 5% of wild-type activity
-
,
734293
5.1.3.37
D452A
about 70% of wild-type activity
734293
5.1.3.37
F122Y
65% residual activity
734159
5.1.3.37
H154F
complete loss of activity
734159
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