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EC Number Protein Variants Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 5.1.2.3G116F both the enoyl-CoA hydratase activity, EC 4.2.1.17 and the 3-hydroxyacyl-CoA epimerase activity, EC 5.1.2.3 are eliminated by the site-directed mutation alpha/Gly116 to Phe. This provides direct evidence that both enzymes are associated with a common active site on the amino-terminal domain of the multifunctional enzyme complex which exhibits the activities of EC 4.2.1.17, EC 2.3.1.16, EC 5.1.2.3, EC 1.1.1.35, and EC 5.3.3.3 2216
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