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EC Number
Protein Variants
Commentary
Reference
4.3.3.2
biotechnology
the enzyme encoding gene is a candidate gene for metabolic engineering of the TIA pathway in Rauwolfia verticillata
695121
4.3.3.2
C97S
loss of activity
716888
4.3.3.2
D177A
mutant engineered for redesigning the substrate specificity
679162
4.3.3.2
D213E
loss of activity
716888
4.3.3.2
D213N
loss of activity
716888
4.3.3.2
E194D
about 30% of wild-type activity
716888
4.3.3.2
E194V
about 55% of wild-type activity
716888
4.3.3.2
E277G
mutant engineered for redesigning the substrate specificity
679162
4.3.3.2
E309A
mutant with 25% decrease of kcat
666582
4.3.3.2
F232T
mutant engineered for redesigning the substrate specificity
679162
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