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EC Number Protein Variants Commentary Reference
Show all pathways known for 4.2.2.21Display the word mapDisplay the reaction diagram Show all sequences 4.2.2.21E608A the mutant does not show detectable activity on either chondroitin 6-sulfate or dermatan sulfate 704643
Show all pathways known for 4.2.2.21Display the word mapDisplay the reaction diagram Show all sequences 4.2.2.21E628D mutant shows no activity 690969, 692529
Show all pathways known for 4.2.2.21Display the word mapDisplay the reaction diagram Show all sequences 4.2.2.21E628Q Km (mM) (chondroitin sulfate A) 0.158, (chondroitin sulfate C) 0.035, kcat (1/sec) (chondroitin sulfate A) 10.38, (chondroitin sulfate B) 4.41, no activity toward dermatan sulfate 690969
Show all pathways known for 4.2.2.21Display the word mapDisplay the reaction diagram Show all sequences 4.2.2.21E653A no enzymic activity 663950, 663965
Show all pathways known for 4.2.2.21Display the word mapDisplay the reaction diagram Show all sequences 4.2.2.21E653D no enzymic activity 663965
Show all pathways known for 4.2.2.21Display the word mapDisplay the reaction diagram Show all sequences 4.2.2.21E653Q 5fold increase in Km-value 663965
Show all pathways known for 4.2.2.21Display the word mapDisplay the reaction diagram Show all sequences 4.2.2.21H344A Km (mM) (chondroitin sulfate A) 0.202, (chondroitin sulfate C) 0.134, kcat (1/sec) (chondroitin sulfate A) 92.66, (chondroitin sulfate B) 35.71, no activity toward dermatan sulfate 692529
Show all pathways known for 4.2.2.21Display the word mapDisplay the reaction diagram Show all sequences 4.2.2.21H344D mutant shows no activity 690969
Show all pathways known for 4.2.2.21Display the word mapDisplay the reaction diagram Show all sequences 4.2.2.21H344E mutant shows no activity 690969
Show all pathways known for 4.2.2.21Display the word mapDisplay the reaction diagram Show all sequences 4.2.2.21H344N Km (mM) (chondroitin sulfate A) 0.039, (chondroitin sulfate C) 0.084, (dermatan sulfate) 0.09, kcat (1/sec) (chondroitin sulfate A) 42.2, (chondroitin sulfate B) 18.7, (dermatan sulfate) 9.06 690969
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