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EC Number Protein Variants Commentary Reference
Show all pathways known for 4.2.2.19Display the word mapDisplay the reaction diagram Show all sequences 4.2.2.19E243A site-directed mutagenesis, Ca2+-binding residue, about 3.6fold reduced activity compared to the wild-type enzyme 652553
Show all pathways known for 4.2.2.19Display the word mapDisplay the reaction diagram Show all sequences 4.2.2.19E243A/E245A site-directed mutagenesis, Ca2+-binding residue, about 4fold reduced activity compared to the wild-type enzyme 652553
Show all pathways known for 4.2.2.19Display the word mapDisplay the reaction diagram Show all sequences 4.2.2.19E245A site-directed mutagenesis, Ca2+-binding residue, about 6fold reduced activity compared to the wild-type enzyme 652553
Show all pathways known for 4.2.2.19Display the word mapDisplay the reaction diagram Show all sequences 4.2.2.19E333A PCR site-directed mutagenesis, E333 is a key residue in catalysis, reduced activity 652290
Show all pathways known for 4.2.2.19Display the word mapDisplay the reaction diagram Show all sequences 4.2.2.19H272A PCR site-directed mutagenesis, H272 is a key residue in catalysis, reduced activity 652290
Show all pathways known for 4.2.2.19Display the word mapDisplay the reaction diagram Show all sequences 4.2.2.19K250A PCR site-directed mutagenesis, inactive mutant 652290
Show all pathways known for 4.2.2.19Display the word mapDisplay the reaction diagram Show all sequences 4.2.2.19N213Q site-directed mutagenesis, Ca2+-binding residue, about 6fold reduced activity compared to the wild-type enzyme 652553
Show all pathways known for 4.2.2.19Display the word mapDisplay the reaction diagram Show all sequences 4.2.2.19R271A PCR site-directed mutagenesis, R271 is a key residue in catalysis 652290
Show all pathways known for 4.2.2.19Display the word mapDisplay the reaction diagram Show all sequences 4.2.2.19R271E site-directed mutagenesis, active site mutant, catalytically inactive 652553
Show all pathways known for 4.2.2.19Display the word mapDisplay the reaction diagram Show all sequences 4.2.2.19R271K site-directed mutagenesis, active site mutant, about 10fold reduced activity compared to the wild-type enzyme 652553
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