EC Number |
Protein Variants |
Reference |
---|
4.1.99.12 | A137T |
naturally occuring Rib3 mutant which is partially deficient in cytochromes a, a3, and cytochrome b, the respiratory defect elicited by this mutation cannot be explained by a flavin insufficiency based on the following evidence: 1. growth of the aE280/U1 on respiratory substrates is not rescued by exogenous riboflavin, 2. the levels of flavin nucleotides are not significantly different in the mutant and wild type, phenotype, overview |
674407 |
4.1.99.12 | C59A |
site-directed mutagenesis, the mutant shows 70% of wild-type enzyme activity |
675342 |
4.1.99.12 | D21E |
site-directed mutagenesis, inactive mutant |
674406 |
4.1.99.12 | D21N |
site-directed mutagenesis, inactive mutant |
674406 |
4.1.99.12 | D30E |
site-directed mutagenesis, inactive mutant |
674406 |
4.1.99.12 | D32A |
site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme |
-, 728745 |
4.1.99.12 | D92A |
site-directed mutagenesis, inactive mutant |
675342 |
4.1.99.12 | E154D |
DBPS activity is abolished |
716533 |
4.1.99.12 | E163A |
site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme |
-, 728745 |
4.1.99.12 | E166A |
site-directed mutagenesis, inactive mutant |
675342 |