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EC Number
Protein Variants
Commentary
Reference
4.1.1.B12
F344H
mutation in conserved amino acid, 41fold increase in Km value for L-lysine, 1.5fold for L-ornithine
728473
4.1.1.B12
F344Y
mutation in conserved amino acid, 2.2fold increase in Km value for L-lysine, 1.5fold for L-ornithine
728473
4.1.1.B12
K118A
site-directed mutagenesis, the mutant shows about 90% reduced activity compared to the wild-type enzyme
748887
4.1.1.B12
M341L
mutation in conserved amino acid, minor changes in Km values
728473
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