EC Number   |
Protein Variants |
Reference |
|---|
    4.1.1.20 | E375A |
site-directed mutagenesis of a substrate binding site residue, the mutant is almost completely inactive |
747000 |
| 4.1.1.20 | I148A |
mutant shows 2% catalytic efficiency compared to the wild type enzyme |
693099 |
| 4.1.1.20 | I148D |
mutant shows 0.2% catalytic efficiency compared to the wild type enzyme |
693099 |
| 4.1.1.20 | I148F |
mutant shows 15% catalytic efficiency compared to the wild type enzyme |
693099 |
| 4.1.1.20 | I148G |
mutant shows 0.5% catalytic efficiency compared to the wild type enzyme |
693099 |
| 4.1.1.20 | I148K |
mutant shows 2% catalytic efficiency compared to the wild type enzyme |
693099 |
| 4.1.1.20 | I148L |
mutant shows 28% catalytic efficiency compared to the wild type enzyme |
693099 |
| 4.1.1.20 | M408A |
site-directed mutagenesis of a substrate binding site residue, the mutant is almost completely inactive |
-, 747000 |
| 4.1.1.20 | N381A |
site-directed mutagenesis, the mutant shows impaired dimerization and is significantly attenuated in catalytic activity |
-, 748217 |
| 4.1.1.20 | R302A |
site-directed mutagenesis of a substrate binding site residue, the mutant shows about 65% reduced activity compared to wild-type |
-, 747000 |
